A5038633156- Global Maternal and Child Health
- Pregnancy-related medical research
- Healthcare Systems and Reforms
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Reproductive Health and Contraception
- Maternal and Perinatal Health Interventions
- Maternal and fetal healthcare
- Viral gastroenteritis research and epidemiology
- Animal Disease Management and Epidemiology
- Menopause: Health Impacts and Treatments
- Traditional Chinese Medicine Studies
- Computational Drug Discovery Methods
- Biomarkers in Disease Mechanisms
- Viral Infections and Vectors
- Viral Infections and Outbreaks Research
- Mosquito-borne diseases and control
- Healthcare Policy and Management
- Cancer Genomics and Diagnostics
- Ferroptosis and cancer prognosis
- Pharmaceutical studies and practices
- Viral Infections and Immunology Research
- Adolescent Sexual and Reproductive Health
- HIV, Drug Use, Sexual Risk
- Diabetes Treatment and Management
- Bioinformatics and Genomic Networks
Eastern Hepatobiliary Surgery Hospital
2023-2024
Second Military Medical University
2023-2024
Central South University
2024
Xiangya Hospital Central South University
2024
Peking University
2023
Beijing Jishuitan Hospital
2023
Sun Yat-sen Memorial Hospital
2021-2022
Sun Yat-sen University
2021-2022
Jiangsu Province Hospital
2021
Nanjing Medical University
2021
Recreational water contaminated with fecal pollution poses a great public health concern, as waste may cause serious waterborne illnesses. Current recreational standards using indicator bacteria (FIB) have their limitations for human protection especially in developing countries such China.To explore the potential use of enteric viruses contamination, four viruses: norovirus geno-groups I and II, enteroviruses, adenoviruses were tested this study molecular detection methods sensitive RT-PC...
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This survey study was conducted to understand the effect of New Cooperative Medical Scheme (NCMS) on farmers’ medical expenses through comparing information from five investigations and obtain a scientific basis for more applicable NCMS. The carried out interviewing farmers in their homes. multi-phase stratified cluster random sampling adopted select 3 counties all 92 Jiangxi province, 9 townships selected counties, 27 villages townships, 60 families each village between 2006 2014,...
Severe fever with thrombocytopenia syndrome (SFTS), an emerging infectious disease caused by a novel bunyavirus, was discovered in rural areas of Central China 2009.A case-control study based on hospital data applied to detect the potential risk sources for SFTS SFTS-endemic counties Hubei Province. Cases were defined as hospitalized SFTSV confirmed patients. Controls randomly selected from non-SFTSV patients same ward within 2 weeks inclusion cases, and they matched age (+/- 5 years) gender...
Preconception care is defined as the promotion of health and well-being a woman her partner before pregnancy. Improving preconception can result in improved reproductive outcomes. China has issued latest version official guideline for 2011. The objective this cross-sectional study to determine whether there variation quality healthcare services distinct eastern northern populations China, what factors are associated with such variation. A survey using our previously developed instrument was...
Abstract Background The World Health Organization (WHO) in 2015 stated that every effort should be made to provide cesarean delivery (CD) for women need. In China, the two-child policy largely prompts number of advanced age childbirth, which raises possibility an increasing who need a c-section. aim this study was assess trends overall and medical indication-classified CD rates era Jiangsu, China. Methods A retrospective cross-sectional 291,448 delivered 11 hospitals Jiangsu province between...
Despite near universal health insurance coverage in China, populations with low incomes may still face barriers access and utilization of affordable care. We aimed to identify the likelihood forgone medical care due cost by surveying individuals from community assess: (1) The percent cost; (2) Factors associated cost. Surveys conducted (2016–2017) Mandarin included demographic utilization-related items. Theoretically-informed, fully-adjusted analyses were employed. Approximately 94%...
Abstract Gallbladder cancer (GBC) is a highly aggressive malignancy lacking clinically available targeted therapeutic agents. Super‐enhancers (SEs) are crucial epigenetic cis‐regulatory elements whose extensive reprogramming drives aberrant transcription in cancers. To study SE GBC, the genomic distribution of H3K27ac profiled multiple GBC tissue and cell line samples to establish landscape its associated core regulatory circuitry (CRC). The biliary lineage factor SOX9 Wnt pathway effector...
Objective: To clarify the age patterns and types of differences so as to provide reference on prevention interventions hand, foot mouth disease (HFMD) cases, in Hubei province. Methods: We collected HFMD case information province from Chinese National Notifiable Infectious Disease Reporting System 2009-2015 while pathogens laboratory monitoring system Center for Control Prevention at all levels All data were stratified by age, severity, confirmation status, serotypes enterovirus. Results:...
Abstract Background Cluster heatmaps are widely used in biology and other fields to uncover clustering patterns data matrices. Most cluster heatmap packages provide utility functions divide the dendrograms at a certain level obtain clusters, but it is often difficult locate appropriate cut dendrogram clusters seen or computed by statistical method. Multiple cuts required if different levels dendrogram. Results We developed DendroX, web app that provides interactive visualization of where...
Precise predictions for nuclei near drip lines are crucial experiments in new generation of rare isotope facilities. A multi-models investigation the $Q_g$ systematics fragments production cross sections, with defined as difference mass excess (ME) between projectile ($Z_{p}, A_{p}$) and fragment ($Z_{f}, A_{f}$) $Q_{g}=ME(Z_{p}, A_{p})-ME(Z_{f}, A_{f})$, has been performed to verify model prediction abilities light neutron-rich isotopes measured $^{40}$Ar + $^9$Be fragmentation reactions...
Objective: Using bioinformatics methods to analyze the core pathogenic genes and related pathways in elderly osteoporosis. Methods: From November 2020 August 2021, eight osteoporosis patients who received treatment five healthy participants underwent physical examinations Beijing Jishuitan Hospital were selected as subjects. The expression level of RNA peripheral blood was collected for high-throughput transcriptome sequencing analysis. gene ontology (GO) analysis Kyoto Encyclopedia Genes...
Background: This study aimed to understand attitudes of HIV/AIDS follow-up workers regarding task shifting, reveal the current conditions this implementation, as well find out any challenges early-stage implementation. Methods: Taking Jiangxi Province an example, a cross-sectional survey with 102 health professionals in CDCs (Centers for Disease Control and Prevention) 92 care providers primary institutions was conducted from November 2016 January 2017. includes demographic backgrounds...
Compared with the median age of breast cancer onset in western countries at 62-64 years, China is around 16 years earlier. There are nearly fifty thousand new patients younger than 40 every year. The tumor characteristics, diagnosis and treatment methods, psychosocial needs these young often different from elder patients. Currently, international clinical guidelines for mainly formulated by countries, which do not address unique China. many questions problems that have standard answer...
Abstract Background The pathophysiological alterations in response to shunt correction patients with pulmonary arterial hypertension associated congenital heart disease (CHD-PAH) is still not clear. Purpose To explore the dynamic plasma metabolite profiling and its relationship clinical characteristics CHD-PAH during perioperative period of defect repair. Methods Plasma samples from 13 were harvested at four time points: before cardiopulmonary bypass (CPB) after anesthesia (Pre), immediately...
Cholangiocarcinoma (CCA) is an aggressive bile duct malignancy with poor prognosis. To improve our understanding of the biological characteristics CCA and develop effective therapies, appropriate preclinical models are required. Here, we established characterized 12 novel patient-derived primary cancer cell (PDPC) using multi-region sampling. At genomic level PDPCs, observed not only commonly mutated genes, such as TP53, JAK3, KMT2C, consistent reports in CCA, but also specific mutation...
Objective To analyze the epidemiological and etiological characteristics of infectious diarrhea cases in Hubei province from 2015 to 2017, so as provide basis for prevention control strategy disease. Methods The information reported 2017 was collected. All data were analyzed by age, gender, confirmed or clinically diagnosed rural urban cases, well characteristics. Results A total 130 336 reported. There no fatal case. The average annual incidence age groups 0-2, 3-6, 7-64 ≥65...
Background: Maternal near miss (MNM) is one of the most vital health indicators reflecting quality obstetric care. The aim this study was to explore causes and change patterns in maternal ratio (MNMR) during era two-child policy Jiangsu Province, China.Methods: A retrospective cross-sectional 247,261 women who were pregnant 11 hospitals Province between January 2012 December 2018 conducted. period divided into 3 stages: baseline, from June 2014; stage 1, July 2014 (time selective begins take...