Marie H. Abildgaard
- Autophagy in Disease and Therapy
- RNA modifications and cancer
- Microtubule and mitosis dynamics
- Cancer-related molecular mechanisms research
- Cannabis and Cannabinoid Research
- Lipid metabolism and biosynthesis
- Cancer-related gene regulation
- RNA regulation and disease
- Polyamine Metabolism and Applications
- Genomics and Chromatin Dynamics
- Epigenetics and DNA Methylation
University of Copenhagen
2019-2021
Danish Cancer Society
2020-2021
University of British Columbia
2017
In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered field. Our knowledge base relevant new technologies also been expanding. Thus, it is important to formulate on a regular basis updated monitoring autophagy different organisms. Despite numerous reviews, there continues be confusion regarding acceptable methods evaluate autophagy, especially multicellular...
Phosphorylation of histone H3 at serine 10 (H3S10ph) by Aurora kinases plays an important role in mitosis; however, H3S10ph also marks regulatory regions inducible genes interphase mammalian cells, implicating mitosis-independent functions. Using the fluorescent ubiquitin-mediated cell cycle indicator (FUCCI), we found that 30% genome mouse embryonic stem cells (ESCs) is marked with H3S10ph. broadly demarcates gene-rich G1 and positively correlated domains early DNA replication timing (RT)...