- Immune Cell Function and Interaction
- Migraine and Headache Studies
- Multiple Sclerosis Research Studies
- Peripheral Neuropathies and Disorders
- Epilepsy research and treatment
- Hereditary Neurological Disorders
- Long-Term Effects of COVID-19
- Polyomavirus and related diseases
- Trigeminal Neuralgia and Treatments
- T-cell and Retrovirus Studies
- Acute Ischemic Stroke Management
- Cytomegalovirus and herpesvirus research
- Vector-Borne Animal Diseases
- Pharmacological Effects and Toxicity Studies
- Plant Virus Research Studies
- Infective Endocarditis Diagnosis and Management
- COVID-19 Clinical Research Studies
- Cerebrovascular and Carotid Artery Diseases
- Psychology and Mental Health
- Health, Nursing, Elderly Care
- Muscle and Compartmental Disorders
- Heart Failure Treatment and Management
- Herpesvirus Infections and Treatments
- Parasites and Host Interactions
- Poisoning and overdose treatments
Hospital Del Mar
2013-2024
Hospital del Mar Research Institute
2016-2024
Hospital Virgen de los Lirios
2024
Centro Universitário Maurício de Nassau
2024
Universitat Pompeu Fabra
2018-2023
Hospital d'Igualada
2021-2022
Hospital Universitari de Vic
2018-2020
Althaia
2019-2020
Universitat Autònoma de Barcelona
2016-2019
Parc de Salut
2013-2016
We evaluated whether stroke severity, functional outcome, and mortality are different in patients with ischemic or without coronavirus disease 2019 (COVID-19) infection.A prospective, observational, multicentre cohort study Catalonia, Spain. Recruitment was consecutive from mid-March to mid-May 2020. Patients had an acute within 48 hours a previous modified Rankin Scale (mRS) score of 0 3. collected demographic data, vascular risk factors, prior mRS score, National Institutes Health Stroke...
Abstract Background Human cytomegalovirus (HCMV) infection has been recently associated with a low risk of multiple sclerosis (MS), yet the basis behind this observation remains uncertain. In study, we aimed to determine in MS patients whether HCMV induces modifications peripheral B cell compartment. Methods serostatus was determined 73 (55 relapsing-remitting (RRMS); 18 progressive (PMS)) and 30 healthy controls, assessing their immunophenotype cytokine production (GM-CSF, IL-6, IL-10,...
Cytomegalovirus (CMV) infection has recently been associated with a lower multiple sclerosis (MS) susceptibility, although it remains controversial whether protective role or is merely an epiphenomenon related to westernization and early-life viral infections. We aimed evaluate CMV serostatus may differ in patients early MS as compared non-early MS, analyzing the putative association of this virus clinical course humoral immune responses against other herpesviruses.Multicentric analysis was...
Abstract Objectives Epilepsy has been associated with cardiovascular comorbidity. This study aimed to assess the potential association between risk factors ( CRF s), antiepileptic drugs AED and etiology. Material Methods A single‐center retrospective epilepsy cohort from decade of 2004–2013 was assessed. Poisson regression models robust variance were estimated obtain prevalence ratios PR ) according prescription Results After excluding patients in monotherapy group vascular etiology or...
Human cytomegalovirus (HCMV) has been recently related with a lower susceptibility to multiple sclerosis (MS). HCMV promotes an adaptive development of NK cells bearing the CD94/NKG2C receptor characteristic phenotypic and functional profile. are proposed play immunoregulatory role in MS, expansion NKG2C(+) subset was associated reduced disability progression. To further explore this issue, additional cell markers, i.e., downregulation FcεRIγ chain (FcRγ) PLZF transcription factor, as well...
Galcanezumab has shown efficacy and effectiveness in the treatment of episodic chronic migraine (CM), however, population represented randomized clinical trials (RCTs) differs from observed real-world setting. To describe long-term tolerability galcanezumab practice patients excluded RCTs.Multicenter prospective cohort study consecutive with high-frequency (HFEM) prior failure to three or more preventive drugs, treated followed up for 12 months.We enrolled 1055 patients, aged 50 (IQR:...
Background and purpose Epilepsy has been associated with cardiovascular comorbidity. Risk prediction equations are the standard tools in primary prevention of disease. Our aim was to compare prevalence risk factors ( CVRF s), statin use people epilepsy PWE ) general population. Methods The s score were compared between 815 from an outpatient register 5336 participants a population cohort. Results People had less hypertension (43.3% vs. 50.4%), diabetes (15.8% 19.2%), more dyslipidemia (40.2%...
<h3>Objective</h3> To determine long-term cardiovascular risk after TIA and to identify the factors associated with increased risk. <h3>Methods</h3> This was a prospective observational registry of patients admitted emergency room our tertiary stroke center from June 2006 January 2016. New vascular events (NVEs) were recorded 3 months onset until 2017, including both nonstroke (coronary peripheral disease). We registered etiology, age, sex, factors, radiologic data, clinical features...
The aim was to evaluate whether adaptive NKG2C+ natural killer (NK) cells, characterized by enhanced antibody-dependent cell cytotoxicity (ADCC), may influence time B repopulation after rituximab treatment in multiple sclerosis (MS) patients.This a prospective observational study of MS patients treated with monitoring peripheral cells for repeated doses. defined as CD19+ above 2% total lymphocytes, classifying cases according the median early or late (≤9 months, >9 respectively). Basal NK...
La mayoría de los estudios muestran que la incidencia del síndrome Guillain-Barré aumenta con edad, un máximo entre 70 y 80 años descenso posterior. El objetivo estudio es describir global específica por sexo grupos edad las características clínicas en comarca Osona (Barcelona, España). Estudio descriptivo retrospectivo base poblacional el periodo 2003-2016. 2,07/100.000 habitantes-año. salvo pequeño pico infancia 40 50 años, alcanzando máxima 6,26/100.000 habitantes-año pasados años. Los...
According to most studies, the incidence of Guillain-Barré syndrome increases with age, a peak occurring between 70 and 80 years age. The objective this study is describe (overall by sex age group) clinical characteristics in Osona (Barcelona, Spain). We performed retrospective, descriptive, population-based covering period 2003 2016. global 2.07 cases per 100 000 person-years. Incidence except for small peaks during childhood 40 50 years, reaches maximum 6.26 person-years above 80....
Exercise may have beneficial effects in MS, remaining controversial its possible disease-modifying and which mechanisms might be involved. We evaluated whether exercise-induced lymphocyte redistribution differ MS patients as compared to controls. was assessed 12 relapsing-remitting 11 controls a cycle ergometer, obtaining blood samples before exercise, at maximal exercise capacity (T1), after resting (T2). Peripheral lymphocytes were by flow cytometry, assessing chemokine receptor expression...
Este artigo aborda os conceitos dos cuidados paliativos na psicologia, entende que de acordo com seus princípios demonstra a necessidade ter um profissional cuide da saúde mental uma vez requer atendimento às demandas doenças e morte o morrer. Aborda processos do luto, as suas fases visão Elizabeth Kubler-Ross. Ressalta importância papel psicólogo no manejo emocional diante todo esse processo, fornecendo apoio aos pacientes famílias para enfrentarem dificuldades emocionais passarem por...
Abstract Background: Differences between migraine with aura (MA) mimicking stroke and ischemic strokes were analyzed to create a predictive diagnostic model.Methods: Prospective cohort of code attended January 2005 June 2020 in tertiary hospital evaluated by vascular neurologist. Data recorded included: Place activation, demographics, risk factors, vitals, initial blood test (glucose, count, electrolytes, coagulation times, D-dimer, fibrinogen C-reactive protein), NIHSS, door-to-onset time,...