A5100723384- Animal Genetics and Reproduction
- Pluripotent Stem Cells Research
- Plant Reproductive Biology
- Plant Molecular Biology Research
- CRISPR and Genetic Engineering
- Seed Germination and Physiology
- Odor and Emission Control Technologies
- Cellular Mechanics and Interactions
- Allelopathy and phytotoxic interactions
- Fungal Biology and Applications
- Trace Elements in Health
- Plant Genetic and Mutation Studies
- Photosynthetic Processes and Mechanisms
- Indoor Air Quality and Microbial Exposure
- Circular RNAs in diseases
- Analytical chemistry methods development
- Semiconductor materials and interfaces
- Atmospheric chemistry and aerosols
- Health disparities and outcomes
- Ubiquitin and proteasome pathways
- Plant responses to water stress
- Polymer-Based Agricultural Enhancements
- Research in Cotton Cultivation
- Flavonoids in Medical Research
- Plant Parasitism and Resistance
Peking University
2024-2025
Institute of Subtropical Agriculture
2023-2024
Chinese Academy of Sciences
2010-2024
Tsinghua University
2009-2024
King University
2024
Vanke (China)
2022-2023
Tsinghua–Berkeley Shenzhen Institute
2023
Nanjing University
2020-2022
Collaborative Innovation Center of Advanced Microstructures
2022
China Agricultural University
2018
Adopting renewable electricity to produce "green" hydrogen has been a critical challenge because at high current density the mass transfer capability of most catalytic electrodes deteriorates significantly. Herein, unique lamellar fern-like alloy aerogel (LFA) electrode, showing dynamically adaptive bubbling and can effectively avoid stress concentration caused by bubble aggregation is reported. The LFA electrode intrinsically highly catalytic-active shows porous, resilient, hierarchically...
The biological mode of action artemisinin, a potent antimalarial, has long been controversial. Previously we established yeast model addressing its mechanism and found mitochondria the key in executing artemisinin's action. Here present data showing that artemisinin directly acts on it inhibits malaria similar way as yeast. Specifically, homologues exhibit correlated activities against yeast, with peroxide bridge playing role for their inhibitory both organisms. In addition, showed...
Chrysin, an active natural bioflavonoid, has been proven to protect against carcinogenesis. However, the role of chrysin in glioblastoma and potential molecular mechanisms remain be elucidated. In our previous study, we found that nuclear factor erythroid 2 (NF-E2)-related (Nrf2) is highly expressed a variety cell lines associated with mitogen-activated protein kinase (MAPK) pathway. The aim this study was evaluate antitumor effects cells how related MAPK/Nrf2 signaling pathway.A Cell...
Cotton fiber development at the stages of elongation and secondary wall synthesis determines traits length strength. To date, mechanisms controlling progression these two phases remain elusive. In this work, function a fiber-preferential actin-binding protein (GhPFN2) was characterized by cytological molecular studies on fibers transgenic green-colored cotton (Gossypium hirsutum) through three successive generations. Overexpression GhPFN2 caused pre-terminated cell elongation, resulting in...
Abstract Introduction Human induced pluripotent stem cells (hiPSCs) are considered as one of the most promising seed cell sources in regenerative medicine. Now hiPSC-based clinical trials underway. To ensure safety, used or therapies should be generated under GMP conditions, and with Xeno-free culture media to avoid possible side effects like immune rejection that by Xeno reagents. However, up now there no reports for hiPSC lines developed completely conditions using Methods Clinical-grade...
Eight new chrysogenolides (A–H (1–8)) and seven known (9–15) 3,5-dimethylorsellinic acid derived meroterpenoids were isolated from the solid substrate fermentation cultures of a Huperzia serrata endophytic fungus, Penicillium chrysogenum MT-12. The structures compounds elucidated by interpretation spectroscopic spectrometric data (1D 2D NMR, IR, HRESIMS). absolute configurations 1–4 determined single-crystal X-ray crystallographic analysis, those 5–8 assigned on basis experimental calculated...
Thermal adaptability is a crucial characteristic for mammalian pathogenic fungi that originally inhabit natural ecosystems. Thermally dimorphic have evolved unique ability to respond host body temperature by shifting from mycelia yeast. The high similarity of protein-coding genes between these and their relatives suggests the indispensable but often overlooked roles non-coding elements in fungal thermal adaptation. Here, we systematically delineated landscape full-length circRNAs both...
As a fundamental and dynamic cytoskeleton network, microfilaments (MFs) are regulated by diverse actin binding proteins (ABPs). Villins one type of ABPs belonging to the villin/gelsolin superfamily, their function is poorly understood in monocotyledonous plants. Here, we report isolation characterization rice (Oryza sativa) mutant defective VILLIN2 (VLN2), which exhibits malformed organs, including twisted roots shoots at seedling stage. Cellular examination revealed that phenotype vln2...
Clioquinol (CQ), a once popular antibiotic, was used to inhibit the growth of microorganisms. Recently, CQ and its analog PBT2 have shown encouraging effects in animal clinical trials for Alzheimer's disease (AD). However, mechanism by which this class molecules works remains controversial. In work, we yeast Saccharomyces cerevisiae as model study how affects molecular cellular functions particularly, copper, iron, zinc homeostasis. We observed CQ-induced inhibition growth, could be slightly...
Here, we show that Arabidopsis ADF10 plays an important role in shaping the overall organization of apical actin filaments by promoting their turnover and ordering. severs depolymerizes vitro is distributed throughout entire pollen tube. In adf10 mutants, severing monomer dissociation events for are reduced, structure extends further toward tube base than wild-type tubes. particular, percentage form large angles to growth axis much higher tubes, more randomly distributed, implying promotes...
There is growing evidence that the mechanical properties of extracellular matrices (ECMs), including elasticity and stress-relaxation, greatly influence function form residing cells. However, effects stress-relaxation are often correlated, making study effect on cellular behaviors difficult. Here, we designed a hybrid network hydrogel with controllable gradient constant elasticity. The crosslinked by covalent bonds dynamic peptide-metal ion coordination interactions. controlled spatially...
Abstract Although seed dormancy of temperate legumes is well understood, less known about it in species that grow subalpine/alpine areas. This study investigated and germination four Vicia from the Tibetan Plateau. Fresh seeds V. sativa were permeable to water, whereas those angustifolia , amoena unijuga had physical (PY). One year dry storage increased proportion impermeable but showed no effect on coat permeability or . Seeds all also non-deep physiological (PD), which was especially...
Background: Good personality is a positive moral in the context of Chinese Confucianism. Based on social-cognitive model normative well-being, we propose that good positively predicts subjective mediated by perceived social support and presence meaning life culture. Methods: In this cross-sectional study, there were 665 adults (134 males 531 females) who participated Personality Questionnaire, Multi-Dimensional Scale Perceived Social Support, Presence Meaning Life Positive Negative Affect...