- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Glioma Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Neurosurgical Procedures and Complications
- Vascular Malformations Diagnosis and Treatment
- Pituitary Gland Disorders and Treatments
- Intraoperative Neuromonitoring and Anesthetic Effects
- Spinal Hematomas and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrospinal fluid and hydrocephalus
- Spinal Fractures and Fixation Techniques
- Optical Imaging and Spectroscopy Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Cervical and Thoracic Myelopathy
- Pain Management and Treatment
- Trauma and Emergency Care Studies
- Adrenal and Paraganglionic Tumors
- COVID-19 and healthcare impacts
- Transcranial Magnetic Stimulation Studies
- Fetal and Pediatric Neurological Disorders
- Spinal Dysraphism and Malformations
- Management of metastatic bone disease
- Pathogenesis and Treatment of Hiccups
- Acute Ischemic Stroke Management
King's College Hospital NHS Foundation Trust
2018-2025
King's College London
2022-2024
King's College Hospital
2018-2022
National Health Service
2021
Royal Hallamshire Hospital
2011-2017
Barking, Havering And Redbridge University Hospitals NHS Trust
2016
University College London
2010-2011
University of Sheffield
2011
Sheffield Teaching Hospitals NHS Foundation Trust
2011
Cervical spondylotic myelopathy (CSM) is the most common cause of spinal dysfunction in elderly. Operative management beneficial for patients with moderate/severe myelopathy. This study examines potential confounding effects age, sex, duration symptoms, and comorbidities on functional outcomes postoperative complications who underwent cervical decompressive surgery.We included consecutive surgery from December 2005 to October 2007. Functional were assessed using Nurick grading system...
Abstract Introduction and objectives The novel severe acute respiratory syndrome coronavirus 2 (COVID-19) pandemic has had drastic effects on global healthcare with the UK amongst countries most severely impacted. aim of this study was to examine how COVID-19 challenged neurosurgical delivery care in a busy tertiary unit serving socio-economically diverse population. Methods A prospective single-centre cohort including all patients referred service or subspecialty multidisciplinary teams...
Background: The simplistic approaches to language circuits are continuously challenged by new findings in brain structure and connectivity. posterior middle frontal gyrus area 55b (pFMG/area55b), particular, has gained a renewed interest the overall network. Methods: This is retrospective single-center cohort study of patients who have undergone awake craniotomy for tumor resection. Navigated transcranial magnetic simulation (nTMS), tractography, intraoperative were correlated with outcomes....
We aim to describe the outcomes after chronic subdural hematoma drainage (CSDH) management in a large cohort of patients on antithrombotic drugs, either antiplatelets or anticoagulants, at presentation and inform clinical decision making timing surgery recommencement these drugs. used data from previous UK-based multi-center, prospective study. Outcomes included recurrence within 60 days, functional outcome discharge, thromboembolic event during hospital stay. performed Cox regression...
Introduction Following endovascular treatment (EVT) or microsurgical (MT) of intracranial aneurysms (IA), radiological follow-up is performed to assess for recurrence and determine the need re-treatment. There a paucity evidence describing long-term results EVT MT IA therefore data inform design protocols are lacking. The overarching aim META study clinically relevant outcomes IA, use this create based clinical these aneurysms.
Multicenter retrospective study.To examine whether posttraumatic cervical spinal canal compromise and cord compression are responsive to changes in motor sensory functions.The maximum (MCC) (MSCC) were developed quantitatively assess stenosis using computed tomographic (CT) scan magnetic resonance imaging (MRI) the setting of acute spine trauma.We included 100 consecutive patients with trauma. Patients classified into three groups as follows: trauma without injury (group 1), incomplete 2),...
Background. Chronic subdural haematoma (CSDH) is a common condition that increases in incidence with rising age. Evacuation of CSDH one the commonest neurosurgical procedures; however optimal peri-operative management, surgical technique, post-operative care and role adjuvant therapies remain controversial. Aim. We propose prospective multi-centre audit order to establish current practices, outcomes national benchmarks for future studies. Methods. Neurosurgical units (NSU) United Kingdom...
The Pipeline Vantage Embolization Device (PEDV) is the fourth-generation pipeline flow diverter for intracranial aneurysm treatment. There are no outcome studies second PEDV version. We aimed to evaluate safety and efficacy outcomes. Primary secondary objectives were determine outcomes unruptured ruptured cohorts, respectively.
OBJECTIVE Most intracranial aneurysms are now treated by endovascular rather than microsurgical procedures. There is evidence to demonstrate superior outcomes for patients with aneurysmal subarachnoid hemorrhage (aSAH) techniques. However, some cases continue require microsurgery. The authors have examined the relationship between number of microsurgery and outcome undergoing treatment aSAH at neurosurgical centers in England. METHODS Neurosurgical National Audit Programme (NNAP) database...
Residents are required to learn a multitude of skills during their microsurgical training. One such skill is the judicious application force when handling delicate tissue. An instrument has been developed that indicates surgeon threshold exceeded by providing vibrotactile feedback. The objective this study was validate use "smart" force-limiting for microsurgery. A laboratory and an in vivo experiment were performed evaluate instrument. In experiment, twelve novice surgeons randomly...
Our aim was to investigate the effectiveness of navigated transcranial magnetic stimulation (nTMS) brain mapping characterise preoperative motor impairment caused by an intradural extramedullary (IDEM) tumour and postoperative cortical functional reorganisation. Preoperative 1-year follow-up clinical, radiological nTMS data from a case thoracic spinal meningioma that underwent surgical resection lesion were collected compared. A 67-year-old patient presented with severe progressive...
There is limited evidence to direct the management of unruptured intracranial aneurysms. Models extrapolated from existing data have been proposed guide treatment recommendations. The aim this study assess whether a consensus-based score (UIATS) or rupture rate estimation model (PHASES) can be used benchmark UK multi-disciplinary team (MDT) practice.Prospective was collected on consecutive series all patients with aneurysms (UIAs) presenting major neurovascular centre between 2012 and 2015....
Objective We describe the chronological trends in cerebral revascularization surgery through a single-surgeon experience; and we review whether context of giant fusiform aneurysms, flow-diverting stents have impacted on use surgery. Methods our single institution prospectively collected database procedures between 2006 2018. Comparing this to endovascular stent procedures, compare treatment aneurysms. patient demographics, procedural incidence, complications, outcomes. Results Between 2018,...
<title>Abstract</title> Purpose To this day there is no consensus regarding evidence of usefulness Intraoperative Neurophysiological Monitoring (IONM). Randomized controlled trials have not been performed in the past mainly because difficulties recruitment control subjects. In study, we propose use Bayesian Networks to assess IONM. Methods Single center retrospective study from January 2020 2022. Patients admitted for cranial neurosurgery with intraoperative neuromonitoring were enrolled. We...