- Neuroendocrine Tumor Research Advances
- RNA modifications and cancer
- Lung Cancer Research Studies
- Lung Cancer Diagnosis and Treatment
- Cancer-related molecular mechanisms research
- Ferroptosis and cancer prognosis
- Transplantation: Methods and Outcomes
- Pancreatic and Hepatic Oncology Research
- Inflammatory Biomarkers in Disease Prognosis
- Medical Imaging Techniques and Applications
- Pleural and Pulmonary Diseases
- Radiomics and Machine Learning in Medical Imaging
- Organ Transplantation Techniques and Outcomes
- Tracheal and airway disorders
- Cardiac Ischemia and Reperfusion
- Airway Management and Intubation Techniques
- Simulation and Modeling Applications
- Neuroblastoma Research and Treatments
- Nutrition, Health and Food Behavior
- Gestational Trophoblastic Disease Studies
- Cancer Mechanisms and Therapy
- Metastasis and carcinoma case studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Cardiac Fibrosis and Remodeling
- Cancer, Lipids, and Metabolism
Qufu Normal University
2025
Harbin Medical University
2008-2024
Fourth Affiliated Hospital of Harbin Medical University
2008-2024
Weatherford College
2023
Hubei University of Medicine
2018-2020
Fudan University Shanghai Cancer Center
2017-2019
Shanghai Cancer Institute
2018-2019
Shanghai Medical College of Fudan University
2009-2019
JAC Motors (China)
2013
Purpose: The systemic inflammation response index (SIRI), based on peripheral neutrophil, monocyte, and lymphocyte counts, was recently emerged used as a novel tool in predicting prognosis different types of cancer. Our aim to investigate the clinical significance preoperative SIRI patients with resectable pancreatic ductal adenocarcinoma (PDAC). Materials methods: developed training cohort 371 PDAC undergoing radical surgery between 2010 2013 validated validation 310 from 2014 2015....
The development of multidrug resistance (MDR) is a major cause for the failure chemotherapy, which requires aid nanomedicine.Here in our study, Cu2+ based metal-organic framework (COF) was firstly developed and employed as carrier delivery glucose oxidase (GOx) doxorubicin (Dox) (COF/GOx/Dox) therapy MDR lung cancers.Our results showed that GOx can catalyze produce H2O2. In mean time, react with GSH then transform into Cu+, resulted depletion. Afterwards, produced Cu+ H2O2 trigger Fenton...
Carbohydrate antigen 19-9 (CA19-9) is not generally considered to be a biomarker in pancreatic neuroendocrine tumors (pNETs), as the majority of pNETs present with normal range CA19-9. The study aimed evaluate role serum CA19-9 levels prognostic factor relatively large number patients pNETs. Consecutive were retrospectively collected from single institution between June 2006 and February 2015. receiver operating characteristic (ROC) curve area under ROC used select cut-off values for...
Patients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD) are prone to diaphragmatic dysfunction. However, dynamic assessment function is complex and difficult, whether the can reflect clinical indicators such as lung in AECOPD patients remains unclear. We studied diaphragm stiffness stiffening rate (DSR) exacerbations ≥ 2 times within 1 year their correlation data, thickening fraction (DTF), function, blood gas values. In total, 112 group C Group D who had Global...
Small cell lung cancer (SCLC) is a highly malignant cancer, and over 70% of patients with SCLC present the metastatic disease. We aimed to explore some novel differentially expressed genes (DEGs) or microRNAs (miRNAs) associated lymph node metastasis SCLC.The DEGs between groups were identified, GO functional KEGG pathway enrichment analyses for these implemented. Subsequently, protein-protein interaction network subnetwork module constructed. Then regulatory networks based on miRNAs,...
To evaluate the performance of radiomics models with combination clinical features in distinguishing non-calcified tuberculosis granuloma (TBG) and lung adenocarcinoma (LAC) small pulmonary nodules.We conducted a retrospective analysis 280 patients nodules confirmed by surgical biopsy from January 2017 to December 2020. Samples were divided into LAC group (n = 143) TBG 137). We assigned them training dataset 196) testing 84). Clinical including gender, age, smoking, CT appearance (size,...
Robotic-assisted thoracic surgery (RATS) via subxiphoid incision may be superior in resection of multiple lung nodules.Outcomes robot-assisted one-stage bilateral lobectomy or segmentectomy intercostal and incisions for ground-glass opacities were analysed.Total 36 cases analysed this study. Thirteen had + segmentectomy, 15 underwent segmentectomies, 8 wedge resection. The average intraoperative blood loss was 110.2 ± 57.8 mL, operation time 154 64.2 min, draining 2.6 3.2 days, postoperative...
The present report concerns an unusual case of extranodal Rosai-Dorfman disease involving the epicardium, mesenterium, pleural cavity and lung. All involved lesions showed characteristics S100-positive histiocytes exhibiting emperipolesis. patient was a 51-year-old woman with 2-year evolution chest distress, dyspnoea oedema. Pathological examination indicated that heart failure, which resulted from constrictive pericarditis, led to fatal outcome this case. Interference severe...
Background Previous reports have confirmed that edaravone has protective effects against ischemia-reperfusion (IR) injury of many organs. In this study, we investigated the effect on preventing IR lung in a canine transplantation model. Methods Twelve weight-matched pairs random-bred dogs were randomized into two groups. Within each pair, one dog served as donor and other recipient. study group, prostaglandin E1(PGE1)(8 μg/kg) was injected pulmonary artery (PA) before occlusion lungs flushed...
This report aims to evaluate the effect of atorvastatin (Ator) on left ventricular systolic function in myocardial infarction (MI) rats. Forty healthy adult Sprague-Dawley rats were randomly divided into four groups: Ator group, MI sham-operation group and normal group. The anterior descending coronary arteries ligated establish model; after modeling, was treated with for 4 consecutive weeks. echocardiographic detection performed; peak velocities, strain rates analyzed using 2D-STI...
T-tubes and airway stents are commonly used but have limited effectiveness frequent complications. A 50-year-old male patient presented with severe tracheal stenosis, affecting an 8.7 cm length of the airway. We employed innovative approach known as external suspension fixation stent using robotic assistance. This method involves surgically attaching to exterior trachea provide support stabilize softened or collapsed segments. designed a C-shaped nickel-titanium alloy successfully fixed it...
Objective To investigate complications in patients after noncardiac thoracotomy hypothyroidism with ST changes. Methods Sixty one undergoing were divided into segment change group(28 having depression≥0.05 mV) and controls(33 patients) according to the results of Holter. All added thyroid hormone, until function gland was normal before thoracotomy. The myocardial ischemia measured by Holter within 48 hours Serum hormones examined radioimmunoassay during, And cardiovascular events foliowed-up...