A5061032381- Rheumatoid Arthritis Research and Therapies
- Bone Metabolism and Diseases
- Systemic Lupus Erythematosus Research
- Monoclonal and Polyclonal Antibodies Research
- Inflammatory Myopathies and Dermatomyositis
- Spondyloarthritis Studies and Treatments
- Autoimmune and Inflammatory Disorders Research
- Psoriasis: Treatment and Pathogenesis
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Systemic Sclerosis and Related Diseases
- Bone health and osteoporosis research
- Bone health and treatments
- Cell Adhesion Molecules Research
- Bone and Joint Diseases
- Adipokines, Inflammation, and Metabolic Diseases
- Medical Coding and Health Information
- Tuberculosis Research and Epidemiology
- Osteoarthritis Treatment and Mechanisms
- Immune Cell Function and Interaction
- Biomarkers in Disease Mechanisms
- Viral Infections and Immunology Research
- Chemokine receptors and signaling
- T-cell and B-cell Immunology
- Drug-Induced Adverse Reactions
- Diagnosis and treatment of tuberculosis
Universidad de Guadalajara
2009-2022
Instituto de Salud Musculoesquelética
2022
Mexican Social Security Institute
2008-2011
Hospital de Especialidades
2008-2011
Objective . To evaluate whether serum titers of second-generation anticyclic citrullinated peptide antibodies (anti-CCP2) are associated with the severity and extent interstitial lung disease in rheumatoid arthritis (RA-ILD). Methods In across-sectional study, 39 RA-ILD patients confirmed by high-resolution computed tomography (HRCT) were compared 42 RA without involvement (RA only). Characteristics related to assessed all anti-CCP2 quantified. Results Higher found only (medians 77.9 versus...
The main cause of death in rheumatoid arthritis (RA) is cardiovascular events. We evaluated the relationship anticyclic citrullinated peptide (anti-CCP) antibody levels with increased carotid intima-media thickness (cIMT) RA patients.Forty-five anti-CCP positive and 37 negative patients, 62 healthy controls (HC) were studied. All groups assessed for atherogenic index plasma (AIP) cIMT. Anti-CCP, C-reactive protein (CRP), tumor necrosis factor alpha (TNFα) interleukin-6 (IL-6) measured by...
Determination of anti-citrullinated peptide antibodies (ACPA) plays a relevant role in the diagnosis rheumatoid arthritis (RA). To date, it is still unclear if use several tests for these autoantibodies same patient offers additional value as compared to performing only one test. Therefore, we evaluated performance using two assays ACPA: second-generation cyclic peptides (anti-CCP2) and anti-mutated citrullinated vimentin (anti-MCV) RA. We three groups: RA (<mml:math...
Rheumatoid arthritis (RA) patients might experience anxiety and depressive symptoms. Deficient vitamin D levels may be a trigger for these conditions. The aim of this study was to determine the frequency depression, symptoms, suicidal risk or ideation in with RA associated serum levels.
Osteoporosis (OP) is highly prevalent in rheumatoid arthritis (RA) and influenced by genetic factors. Single-nucleotide polymorphism (SNP) rs2073618 the TNFRSF11B osteoprotegerin ( OPG ) gene has been related to postmenopausal OP although, date, no information described concerning whether this implied abnormalities of bone mineral density (BMD) RA. We evaluated, a case-control study performed Mexican-Mestizo women with RA, SNP associated decrease BMD. RA patients were classified as follows:...
Objective. To compare the modifications in lipids between patients with rheumatoid arthritis (RA) receiving etanercept plus methotrexate (ETA + MTX) versus (MTX) and their relationship serum levels of tumor necrosis factor-alpha (TNF-α). Methods. In an observational cohort study, we compared changes lipid ETA MTX RA. These groups were assessed at baseline 4 24 weeks, measuring clinical outcomes, total cholesterol, triglycerides, high-density lipoprotein cholesterol (HDL-C), low-density...
Objectives The presence of myositis-specific antibodies (MSA), was recently reported in healthy individuals, cancer patients without myopathy and paraneoplastic rheumatic syndromes. We sought to analyze the frequency MSA, myositis-associated (MAA) autoantibodies related systemic autoimmune diseases (SARD) breast patients.Methods One hundred fifty-two were enrolled a cross-sectional study. Clinical information collected, tested by immunoprecipitation an 35S-methionine-labeled K562 cell...
Fracture risk assessment tool (FRAX) index was developed for estimating of the 10-year major or hip osteoporotic fracture. To date, there is insufficient information regarding correlation between FRAX and serum bone turnover markers (BTMs), such as soluble ligand receptor activator nuclear factor-κB (sRANKL), osteoprotegerin (OPG), other molecules related with secondary osteoporosis in rheumatoid arthritis (RA). Therefore, this study aimed at assessing levels sRANKL, OPG, sRANKL/OPG ratio,...
There is a significant rate of therapeutic failure in rheumatoid arthritis (RA) patients treated with leflunomide (LEF). This study investigates the utility values teriflunomide levels (A77 1726) identifying RA who remained moderate or severe disease activity after treatment LEF. In this cross-sectional study, we compared: (a) achieved DAS28-ESR ≤ 3.2, and (b) maintained > 3.2 treatment. ROC curves determined cut-off A77 1726 better performance to identify achieving 3.2. Of 115 LEF, 69 (60%)...
To evaluate the association between circulating leptin and bone mineral density (BMD) in patients with rheumatoid arthritis (RA).One-hundred thirty postmenopausal women RA were assessed for body mass index (BMI), disease characteristics, history of drug use, factor, erythrocyte sedimentation rate (ESR). BMD (g/cm(2)) was determined hip spine by DEXA. Serum concentrations measured ELISA. Spearman's correlation coefficients (rho) other variables. A multiple regression analysis used to adjust...
<h3>Background</h3> Sclerostin (SOST) and dickkopf-1 (DKK1) are involved in the development of primary osteoporosis. Although to date, it is controverted does exist about if serum levels these molecules may reflex adequately a subgroup patients with decrement Bone Mineral Density (BMD) being useful as clinical biomarkers. Some non-conclusive observations made postmenopausal osteoporosis have shown abnormalities levels. To there lack information associated decrease BMD RA. This relevant for...