A5087382410- Fermentation and Sensory Analysis
- Biofuel production and bioconversion
- Microbial Metabolic Engineering and Bioproduction
- Horticultural and Viticultural Research
- Hepatocellular Carcinoma Treatment and Prognosis
- Fungal and yeast genetics research
- Phytochemicals and Antioxidant Activities
- Botanical Research and Applications
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Renal cell carcinoma treatment
- Urinary and Genital Oncology Studies
- Plant Gene Expression Analysis
- Plant biochemistry and biosynthesis
- Liver Disease and Transplantation
- Fungal Biology and Applications
- Bladder and Urothelial Cancer Treatments
- Chemical synthesis and alkaloids
- Plant and animal studies
- Multiple and Secondary Primary Cancers
- Cancer-related molecular mechanisms research
- Kidney Stones and Urolithiasis Treatments
- Banana Cultivation and Research
- Date Palm Research Studies
- Cassava research and cyanide
- Biochemical and biochemical processes
Guizhou Institute of Technology
2020-2025
Ningbo University
2017-2023
Chongqing Three Gorges Central Hospital
2017-2019
Zhejiang University
2019
Sir Run Run Shaw Hospital
2019
China Agricultural University
2015-2017
Hanseniaspora uvarum, a non-Saccharomyces cerevisiae species, has crucial effect on the aroma characteristics of fruit wines, thus, attracting significant research interest in recent years. In this study, H. uvarum-Saccharomyces mixed fermentation was used to ferment Rosa roxburghii Tratt, blueberry wine, and plum wines using either co-inoculated or sequentially inoculated approach. The three wines' volatile were analyzed by headspace-solid-phase microextraction-gas chromatography-mass...
This study elucidates the adaptive mechanisms of Saccharomyces cerevisiae CZ under octanoic acid stress, revealing concentration-dependent growth inhibition (76% lethality at 800 mg/L) and notable tolerance 600 mg/L. Initial exposure (≤6 h) showed no impairment, but prolonged treatment induced dose-dependent lethality, accompanied by reduced H+/K+-ATPase activity elevated malondialdehyde (MDA) levels, indicative oxidative damage. Transcriptomic profiling 5665 genes highlighted predominant...
The significant magnetostrictive effect of amorphous alloy leads to severe vibration iron core and debris shedding, which limits the wide application materials in transformer field. Therefore, characteristics coil are analyzed this paper. Firstly, a mathematical model for predicting material is constructed, accurately measured with help high-precision laser tester. This can reflect under effect. Secondly, noise single frame analyzed. An rated capacity 50 kVA was used as experimental object...
The young shoots of the tea plant Baiye No. 1 display an albino phenotype in early spring under low environmental temperatures, and leaves re-green like those common cultivars during warm season. Periodic albinism is precisely regulated by a complex gene network that leads to metabolic differences enhances nutritional value leaves. Here, we identified messenger RNAs (mRNAs), long noncoding (lncRNAs), circular (circRNAs), microRNAs (miRNAs) construct competing endogenous RNA (ceRNA)...
Betalains replace anthocyanins as color pigments in most families of Caryophyllales. Unlike anthocyanins, betalains are derived from tyrosine via three enzymatic steps: hydroxylation L-tyrosine to L-3,4-dihydroxyphenylalanine (L-DOPA; step 1), and conversion L-DOPA betalamic acid (step 2), cyclo-DOPA (cDOPA; 3). The principal enzymes responsible for these reactions have been elucidated at the molecular level, but their subcellular localizations not explored; hence, intracellular compartments...
Although standard treatment recommendations for urethral carcinoma are lacking due to its rare incidence, infusion chemotherapy can be a good choice therapy which minimizes damage patients compared radical cystourethrectomy and radiation therapy. In this work, pirarubicin loaded Fe 3 O 4 @ZnO core–shell nanoparticles have been successfully synthesized. They magnetically position in tubular structure at will realized on-demand release re-absorption under UV darkness. As result, they strongly...
The purpose of this study was to investigate the efficacy and safety drug-eluting beads transarterial chemoembolization (DEB-TACE) treatment in Chinese hepatocellular carcinoma (HCC) patients prognostic factors for response as well survival. A total 275 HCC were included prospective study. Treatment assessed by modified Response Evaluation Criteria Solid Tumors (mRECIST), progression-free survival (PFS) overall (OS) determined. Liver function adverse events (AEs) before after DEB-TACE...
Cancer Biotherapy and Radiopharmaceuticals officially retracts the paper entitled, "MiR-17 Regulates Prostate Cell Proliferation Apoptosis Through Inhibiting JAK-STAT3 Signaling Pathway," by Hong Dai, Chunmei Wang, Zhihai Yu, Donglin He, Kun Yin Liu, Sheng Wang (Cancer Biother Radiopharm 2018;33(3):103–109. doi: 10.1089/cbr.2017.2386) due to authors' admission that was submitted a mill. A message from corresponding author reads as follows: "I'm very sorry tell you some of experiments in this...
This study aimed to investigate the efficacy, safety, and prognostic factors of drug-eluting beads transarterial chemoembolization (DEB-TACE) in treating Chinese patients with liver cancer. A total 367 cancer from 24 medical centers were consecutively enrolled this multiple-center, prospective cohort study, including 275 hepatocellular carcinoma (HCC) cases, 37 intrahepatic cholangiocarcinoma (ICC) 55 secondary cases. All received CalliSpheres ® DEB-TACE treatment. Treatment response,...
Abstract Background Wickerhamomyces anomalus ( W. ) is a kind of non- Saccharomyces yeast that has variety unique physiological characteristics and metabolic features widely used in many fields, such as food preservation, biomass energy, aquaculture feed protein production. However, the mechanism response to ethanol stress still unclear, which greatly limits its application production beverages fuels. Therefore, we checked effects on morphology, growth, differentially expressed genes (DEGs)...
Abstract This study aimed to investigate the efficacy and safety of drug-eluting beads (DEB) transarterial chemoembolization (TACE) treatment in Chinese intrahepatic cholangiocarcinoma (ICC) patients. 37 ICC patients underwent DEB-TACE CTILC (registered on clinicaltrials.gov with registry No. NCT03317483) were included this present study. Treatment response was assessed according modified Response Evaluation Criteria Solid Tumors (mRECIST). Overall survival (OS) calculated from time...
Oenological yeasts play a critical role in the winemaking process. In this study, biodiversity of non-Saccharomyces yeast was analyzed and monitored using high-throughput sequencing culture-dependent approaches. fermentation characteristics these native were further investigated. A total 241 fungus species 5 culturable detected approaches, respectively. Five strains aroma-producing (K4, K14, K19, K21, K26) isolated, their growth characteristics, carbon source utilization, hydrogen sulfide...
This study was conducted to explore the diagnostic value of microRNA-143 (miRNA-143) in predicting in-stent restenosis (ISR) lower extremity arterial occlusive disease (LEAOD).From February 2012 March 2015, 165 patients (112 males and 53 females) with LEAOD undergoing interventional treatment were enrolled this study. Serum miRNA-143 expression detected using quantitative real-time polymerase chain reaction (qRT-PCR). Patients assigned into non-restenosis groups according routine...
A 1670 bp 5′-flanking region of the polyphenol oxidase (PPO) gene was isolated from red Swiss chard, a betalain-producing plant. This region, named promoter BvcPPOP, and its 5′-truncated versions were fused with GUS introduced into Arabidopsis, an anthocyanins-producing histochemical staining quantitative analysis transgenic plants at vegetative reproductive stages showed that BvcPPOP could direct expression in organs root- petiole-preference, but not including inflorescences shoot, leaf,...
Purpose The purpose of this paper is to identify and analyse the fermentative properties a strain indigenous Wickerhamomyces anomalus ( W. ) from Rosa roxburghii Tratt R. ). Design/methodology/approach Morphological molecular methods were used determine species selected C11. physiological tolerances glucose, ethanol, citric acid sulphur dioxide (SO 2 further assessed by checking growth cells, oenological performances proved measure related wines. Findings C11 could be grown faster than...
Abstract The β-glucosidase properties from one yeast isolate identified as Wickerhamomyces anomalus C4 were characterised. activity of W. was 41.83 ± 0.25 mU/mL, and the optimum temperature pH 40 °C 5.0, respectively. glucose, 10% v/v ethanol 10 mmol/L Cu 2+ inhibited β-glycosidases activities. had a stronger alcohol metabolism capacity than commercial Saccharomyces cerevisiae X16. Besides, fermentation with alone co-fermentations S. X16 reduced volatile acids content sourness value compared...
Wickerhamomyces anomalus ( W. ) is widely reported in the brewing industry and has positive effects on aromatic profiles of wines because its unique physiological characteristics metabolic features. However, accumulation ethanol during fermentation inhibits growth anomalus. Thiamine involved response against various abiotic stresses microorganisms. Therefore, we used transcriptomic metabolomic analyses to study effect thiamine ethanol-stressed . The results indicate that could alleviate...
Wine produced by fermentation of Chestnut rose (Rosa roxburghii) hips, known as cili (Chinese-Mandarin), in Guizhou province, and other places China is becoming popular but there limited knowledge suitable yeast strains for its production. In this study, we first investigated the oenological properties six commercial S. cerevisiae (X16, F33, SH12, GV107, S102, RMS2), one Saccharomyces var. bayanus (S103), commercial, non-Saccharomyces strain, Torulaspora delbrueckii Prelude, indigenous CZ,...
Abstract Oenological yeasts play a crucial role in the winemaking process by converting sugar into ethanol, carbon dioxide and flavor substances that contribute to wine aroma profile. Eighty strains of yeast were isolated from Rosa roxburghii Tratt. Three indigenous (numbered as C26, C31 F110) selected based on having strongest fruity-aroma producing ability further evaluate theirs oenological properties, they identified Hanseniaspora uvarum morphological molecular analyses. Strains...
BACKGROUND The aims of this study were to investigate the expression methylenetetrahydrofolate dehydrogenase 1 (MTHFD1) in human tissue containing clear cell renal carcinoma (CCRCC) compared with normal tissue, and effects upregulating MTHFD1 CCRCC line, Caki-1. MATERIAL AND METHODS Tumor adjacent obtained from 44 patients who underwent radical nephrectomy for CCRCC. Caki-1 cells divided into control group, empty vector (EV) plasmid-treated group that overexpressed MTHFD1. mRNA protein...
Abstract The aim of this study was to identify the locations and harvest months in Guizhou province, China, producing most suitable red dragon fruit ( Hylocereus polyrhizus ) for winemaking. Fruit from Guanling, Luodian Zhenfeng counties harvested separately successive cycles August, September October, respectively. key traits measured were weight, pulp yield, soluble solids content, titratable acid. Wine characteristics alcohol total carbohydrates, acidity, volatile betacyanin content....