A5011575264- Protein Hydrolysis and Bioactive Peptides
- Phytochemicals and Antioxidant Activities
- Postharvest Quality and Shelf Life Management
- Meat and Animal Product Quality
- Tannin, Tannase and Anticancer Activities
- Nanocomposite Films for Food Packaging
- Biochemical effects in animals
- Proteins in Food Systems
- Nuts composition and effects
- Cancer, Hypoxia, and Metabolism
- Enzyme Catalysis and Immobilization
- Cancer Mechanisms and Therapy
- Plant Stress Responses and Tolerance
- Phytochemical compounds biological activities
- Mitochondrial Function and Pathology
- Edible Oils Quality and Analysis
- RNA Research and Splicing
- Salivary Gland Disorders and Functions
- Amino Acid Enzymes and Metabolism
- Biochemical and biochemical processes
- Moringa oleifera research and applications
- Flavonoids in Medical Research
- Medicinal Plants and Bioactive Compounds
- Biochemical and Structural Characterization
- Genetic factors in colorectal cancer
Zhejiang A & F University
2012-2025
Southwest Medical University
2025
Shanghai Jiao Tong University
2018-2024
Shanghai Ninth People's Hospital
2019-2024
Xinjiang Institute of Engineering
2021-2022
Alderson Broaddus University
2021
XinHua Hospital
2018
Zero to Three
2012
Zhejiang University
2008
Xinqiao Hospital
2002
In recent years, food-derived hypoglycemic peptides have received a lot of attention in the study active peptides, but their anti-diabetic mechanism action is not yet clear. this study, camellia seed cake protein (CSCP) was used to prepare with α-glucosidase inhibition. The optimization preparation hydrolyzed (CSCPH) conducted via response surface methodology (RSM) using protamex inhibition as an indicator. optimal hydrolysis conditions were pH 7.11, 4300 U/g enzyme concentration, 50 °C...
Ovarian cancer is a disease that continues to cause mortality in female individuals worldwide. challenging treat due emerging resistance chemotherapy, therefore, the identification of effective novel chemotherapeutic agents important. Polyphenols have demonstrated potential reducing risk developing numerous types cancer, as well progression, their ability reduce cell viability and vascular endothelial growth factor (VEGF) expression. In present study, eight phenolic compounds were screened...
The camellia seed cake proteins (CP) used in this study were individually hydrolyzed with neutral protease, alkaline papain, and trypsin. results showed that the hydrolysate had highest ACE inhibitory activity at 67.36 ± 0.80% after four hours of protease hydrolysis. Val-Val-Val-Pro-Gln-Asn (VVVPQN) was then obtained through ultrafiltration, Sephadex G-25 gel chromatography separation, LC-MS/MS analysis, silico screening. VVVPQN an IC50 value 0.13 mg/mL (198.66 μmol/L), it inhibited a...
Three walnut (Juglans regia L.) drying methods (sun drying, direct oven and intermittent drying) were employed, the consequent changes in lipid oxidation attributes, such as acid value (AV), peroxide (POV), saponification (SV), fatty composition, antioxidant activity [including reducing power, superoxide anion scavenging activity, 1,1-diphenyl-2-picrylhydrazyl free radical (DPPH), lipoxygenase (LOX) total phenols content (TPC), flavonoids (TFC)] investigated this study. Sun resulted highest...
meal has a high protein content and an appropriate amino acid ratio, making it excellent source for producing ACE inhibitory peptides. To promote its application in food, medicine, other fields, alkaline protease hydrolysate of
Carya cathayensis Sarg meal (CM) is a by-product of the edible kernel during oil manufacture. In order to improve wastes utilization, CM derived peptides (CMPs) that showed an in vitro radical scavenging ability were firstly prepared by five different hydrolases. Alcalase treatment revealed highest yield and optimal conditions further determined response surface methodology (RSM), under which reached 35.84%. Simulated gastrointestinal digestion led enrichment low molecular weight (MW) (<3...
Abstract BACKGROUND: The aim of the present study was to reveal effect fruit maturity on chilling tolerance cucumber ( Cucumis sativus L.) and oxidative antioxidative mechanisms involved. Chinese mini‐cucumber (cv. Hangcui‐1) fruits were harvested at four developmental stages: Immature (3–8 days after anthesis (DAA)), Mature (9–16 DAA), Breaker (17–22 DAA) Yellow (35–40 DAA). All stored 2 °C for 9 rewarmed 20 days. RESULTS: injury index declined with advancing maturity. High superoxide anion...
Colorectal cancer (CRC) is one of the most malignant cancers, and its incidence still steadily increasing. The DDX RNA helicase family members have been found to play a role in various cancers; however, DDX54 colorectal unclear needed be defined. Here, we was overexpressed CRC tissues by label-free mass spectrum, which also verified tissue microarray colon cancer, as well cell lines TCGA database. High level correlated with tumor stage distant metastasis, always indicated poor prognosis...
Pecan (Carya cathayensis) is an important economic crop, and its hydrolyzed peptides have been evidenced to reduce the effect of oxidative stress due their antioxidant capacity. Hence, protocols ultrafiltration gel filtration chromatography were established obtain bioactive from by-products C. cathayensis (pecan cake). As measured by DPPH/ABTS radical scavenging, with less molecular weight (MW) possess higher PCPH-III (MW < 3 kDa) presented scavenging capacity than PCPH-II (3 kDa MW 10...
The gene expression patterns of antioxidative enzymes in cucumber (Cucumis sativus L.) fruits at four different maturity stages, immature (3-8 d after anthesis (DAA), mature (9-16 DAA), breaker (17-22 and yellow (35-40 were determined before cold storage 2°C for 9 subsequent rewarming 20°C 2 d. electrolyte leakage malondialdehyde content increased rewarming. Increased expressions peroxidase, ascorbate peroxidase (APX), monodehydroascorbate reductase played an important role to cope with...
Glutathione synthetase deficiency (GSSD) is a rare inborn error of glutathione metabolism with autosomal recessive inheritance. The severe form the disease characterized by acute metabolic acidosis, usually present in neonatal period hemolytic anemia and progressive encephalopathy. A case male newborn infant who had acidosis high anion gap, anemia, hyperbilirubinemia reported. level 5-oxoproline was detected his urine diagnosis generalized GSSD made. DNA sequence analysis revealed to be...
Ovarian cancer (OC) is among the top gynecologic cancers in US with a death tally of 13,940 past year alone. Gallic acid (GA) natural compound pharmacological benefits. In this research, role GA on cell proliferation, apoptosis, cycle-related protein expression was explored OC lines OVCAR-3 and A2780/CP70. After 24,48 72 h treatment, IC50 values cells were 22.14 ± 0.45, 20.36 0.18, 15.13 0.53 μM, respectively A2780/CP70 33.53 2.64, 27.18 0.22, 22.81 0.56, respectively. Hoechst 33,342 DNA...
Ovarian cancer is the second most common gynecologic with an estimated 13,940 mortalities across United States in 2020. Natural polyphenols have been shown to double survival time of some patients due their anticancer properties. Therefore, effect extracted from Chinese hickory seed skin Carya cathayensis (CHSP) on ovarian was investigated present study. Cell viability results showed that CHSP more effective inhibiting cells than normal cells, IC50 value for inhibition cell proliferation...
Okara cellulose is a highly abundant, green, sustainable, and biodegradable polymer with many potential industrial applications. In this study, we fabricated composite hydrogels okara nanofibers (CNFs) chitosan (CH) by hydrating, sonicating, heating them at 100 °C for 30 min, then induced their assembly cooling. The effects of CNF (with without 2,2,6,6-tetramethylpiperidinyloxy (TEMPO) oxidation) CH concentration on the structure properties was examined, including microstructure, surface...
The development of an effective drying method to extend the shelf life raw Chinese hickory (Carya cathayensis) is a major postharvest processing in nut industry. In this paper, effect seed size and temperature on hot air kinetics quality were detected. Our results reveal that greatly affects final equilibrium moisture content hickory. So, we predict larger must be dried at higher temperature. An Arrhenius-type relationship found between diffusivity (Deff) where activation energy 40.85...