- Child and Animal Learning Development
- Psychosomatic Disorders and Their Treatments
- Mental Health Treatment and Access
- Language Development and Disorders
- Schizophrenia research and treatment
- Memory Processes and Influences
- Epilepsy research and treatment
- Educational Strategies and Epistemologies
- Autoimmune and Inflammatory Disorders Research
- Adolescent and Pediatric Healthcare
- Communication in Education and Healthcare
- Child and Adolescent Psychosocial and Emotional Development
- Mental Health and Psychiatry
- Central Venous Catheters and Hemodialysis
- Radiomics and Machine Learning in Medical Imaging
- Employment and Welfare Studies
- Vascular Procedures and Complications
- Health Systems, Economic Evaluations, Quality of Life
- Early Childhood Education and Development
- Palliative Care and End-of-Life Issues
- Family and Patient Care in Intensive Care Units
- Global Maternal and Child Health
- Lung Cancer Diagnosis and Treatment
- Pharmacological Effects and Toxicity Studies
- Obsessive-Compulsive Spectrum Disorders
King's College London
2016-2024
Royal Marsden NHS Foundation Trust
2020-2024
University of New Hampshire
2023
Muscular Dystrophy UK
2023
Great Ormond Street Hospital
2017-2022
University College London
2017-2022
The Royal Wolverhampton NHS Trust
2022
New Cross Hospital
2022
Royal Marsden Hospital
2022
Queen Mary's Hospital
2021
Dissociative seizures are paroxysmal events resembling epilepsy or syncope with characteristic features that allow them to be distinguished from other medical conditions. We aimed compare the effectiveness of cognitive behavioural therapy (CBT) plus standardised care alone for reduction dissociative seizure frequency.In this pragmatic, parallel-arm, multicentre randomised controlled trial, we initially recruited participants at 27 neurology services in England, Scotland, and Wales. Adults...
Background. A neuropsychological formulation of schizophrenia has suggested that problems with meta-representation underpin both positive and negative symptoms. This study tested Frith's account by asking patients experiencing an acute episode psychosis to complete a set tasks involved Theory Mind (ToM) skills. Methods. Fourteen who fulfilled criteria for schizophrenia, 10 deluded were suffering from psychotic disorders other than 12 depressed completed second-order false belief tasks, test...
We observed the relief of hot flashes in breast cancer survivors taking tamoxifen and treated with sertraline for depression. Our objective was to assess effect on frequency severity flashes, mood status, health-related quality life. used a randomized, double-blind, placebo-controlled, crossover study using 6 weeks (50 mg each morning) versus placebo. Study participants were 62 from an oncology clinic tertiary care center adjuvant reporting bothersome flashes. Patients asked keep daily flash...
Abstract Background In England, during 2009–2014 the ‘Time to Change’ anti-stigma programme has included a social marketing campaign (SMC) using mass media channels, and contact events but efficacy of such approach not been evaluated yet. Methods The target population people aged between mid-twenties/mid-forties, from middle-income groups. Participants were recruited through an online market research panel, before after each burst (with mean number unique participants per burst: 956.9 ±...
Objective To investigate whether public knowledge, attitudes, desire for social distance and reported contact in relation to people with mental health problems have improved England during the Time Change (TTC) programme reduce stigma discrimination 2009–2015. Methods Using data from an annual face‐to‐face survey of a nationally representative sample adults, we analysed longitudinal trends outcomes regression modelling using standardised scores measures overall by age gender subgroups....
BackgroundSurveillance is universally recommended for non-small cell lung cancer (NSCLC) patients treated with curative-intent radiotherapy. High-quality evidence to inform optimal surveillance strategies lacking. Machine learning demonstrates promise in accurate outcome prediction a variety of health conditions. The purpose this study was utilise readily available patient, tumour, and treatment data develop, validate externally test machine models predicting recurrence, recurrence-free...
In the experiments reported here, children chose either to maintain their initial belief about an object's identity or accept experimenter's contradicting suggestion. Both 3– 4–year–olds and 4– 5–year–olds were good at accepting suggestion only when experimenter was better informed than they (implicit source monitoring). They less accurate recalling both own information access (explicit recall of experience), though performed well above chance. Children least reporting whether final based on...
BackgroundAnti-stigma programmes should aim to increase disclosure those who can support someone with a mental health problem and appropriate professional help-seeking.AimsWe investigated associations among public awareness of England's Time Change anti-stigma campaign and: (a) comfort envisaged in disclosing family friends; (b) an employer; (c) intended help-seeking from general practitioner, i.e. physician working primary care.MethodUsing data survey nationally representative sample...
Patient and public involvement engagement is an important expected component of health-related research activity in the UK. Specifically within health sphere, (usually defined as raising awareness research) patient actively involving people have traditionally been seen separate but much to gain from working together towards a common goal better outcomes for all.This paper describes unique approach taken by Public Programmes Team: small interdisciplinary team specialists, with backgrounds...
Abstract Background England’s Time to Change programme reduce mental health-related stigma and discrimination included a social marketing campaign using traditional media, targeted middle-income groups aged 25–45 between 2009 2016. From 2017, the same age group on low middle incomes were targeted, content focused men’s health, by changing advertising adapting ‘key messages’. This study investigates changes in stigma-related public knowledge, attitudes desire for distance England since began...
Sexual minority adolescents (i.e. youth not exclusively heterosexual) report more anxiety than heterosexual on symptom questionnaires but no research has used standardised diagnostic tools to investigate disorder risk. This study uses a UK birth cohort the risk of disorders in sexual and using computerised structured clinical interview explores influence gender nonconformity, bullying self-esteem.Participants were 4,564 (2,567 girls 1,996 boys) from Avon Longitudinal Study Parents Children...
Abstract Objective We aimed to characterize the demographics of adults with dissociative (nonepileptic) seizures, placing emphasis on distribution age at onset, male:female ratio, levels deprivation, and seizure semiology. Methods collected demographic clinical data from 698 seizures recruited screening phase CODES (Cognitive Behavioural Therapy vs Standardised Medical Care for Adults With Dissociative Non‐Epileptic Seizures) trial 27 neurology/specialist epilepsy clinics in UK. described...
The role of paclitaxel-coated balloons has been established in the coronary and peripheral arterial circulations with recent interest use to improve patency rates following angioplasty arteriovenous fistulas. To assess efficacy prolong survival time target lesion primary fistulas, we designed an investigator-led multi-center randomized controlled trial follow up variable for a minimum one year. Patients fistula who were undergoing clinical indication included but patients or more lesions...
Abstract Background Our aim was to investigate patterns of change in public knowledge, attitudes, desire for social distance and reporting having contact with people mental health problems England during the Time Change (TTC) programme reduce stigma discrimination 2009–2017. Methods Using data from an annual face-to-face survey a nationally representative quota sample adults, we evaluated longitudinal trends outcome measures regression analyses made assumptions on basis simple random sample....
Scientists and health communication professionals expressed frustration over the relationship between misinformation circulating on Internet global public perceptions of responses to Ebola epidemic originating in West Africa. Using big data platform Media Cloud, we analyzed all English-language stories about keyword "Ebola" published from 1 July 2014 17 November media sets U.S. Mainstream Media, Regional Political Blogs, Popular Europe Monitor, Global Voices understand how social network...
Discrimination reported by mental health service users in England is high. The study aims to determine changes health-related discrimination from 2008 2014.Samples of were interviewed 2014 using the and Stigma Scale version 12. Social capital terms access social resources a marker effects on connections, so 2011, also measured Resource Generator-UK.Fewer participants one or more life areas compared (OR: 0.58, 95% CI 0.36 0.94 P = 0.03). A weighted multiple regression model found decrease...
The present study was designed to (1) establish current sedation practice in UK critical care inform evidence synthesis and potential future primary research (2) compare reported via a survey with actual assessed point prevalence (PPS). adult general units were invited participate of practice, representative sample PPS at the patient level. Survey responses compared data where both available. received from 214 (91 %) 235 eligible units. Of these respondents, 57 % having written protocol, 94...
This paper reports guidelines for the content of statistical analysis plans early phase clinical trials, ensuring specification minimum reporting requirements, by detailing extensions (11 new items) and modifications (25 to existing guidance after a review various stakeholders.
Cranioplasty is a technically simple procedure, although one with potentially high rates of complications. The ideal timing cranioplasty should minimize the risk complications, but research investigating and complications has generated diverse findings. Previous studies have included mixed populations patients undergoing following decompression for traumatic, vascular, other cerebral insults, making results challenging to interpret. objective current study was examine associated...
There is ongoing debate regarding the culture of competitive women's sports. On one hand, women who participate in sports are viewed as adhering to and reinforcing heteronormative stereotypes hegemonic masculinity. Conversely, an inherently supportive environment for those involved. The current study explored latter phenomena, specifically related factors that promote inclusive empowering community LGBTQ+ women. Eleven individual semi-structured interviews follow-up focus group with six...