A5029824396- Animal Virus Infections Studies
- Veterinary Pharmacology and Anesthesia
- Animal testing and alternatives
- Virus-based gene therapy research
- Cephalopods and Marine Biology
- Human-Animal Interaction Studies
- Viral gastroenteritis research and epidemiology
- Herpesvirus Infections and Treatments
- Virology and Viral Diseases
- Mosquito-borne diseases and control
- Insect and Pesticide Research
- Viral Infectious Diseases and Gene Expression in Insects
- Zoonotic diseases and public health
- Plant Virus Research Studies
- Meat and Animal Product Quality
- Stress Responses and Cortisol
- Effects of Environmental Stressors on Livestock
- Respiratory viral infections research
- Animal Behavior and Welfare Studies
- Parvovirus B19 Infection Studies
- Biological Control of Invasive Species
- HIV Research and Treatment
- Infectious Encephalopathies and Encephalitis
- Agriculture and Farm Safety
- Advanced Drug Delivery Systems
Netherlands Institute for Neuroscience
2022-2024
Trinity College Dublin
2019-2023
Royal Netherlands Academy of Arts and Sciences
2022
University of Edinburgh
2022
University of Bologna
2009-2018
Nasal administration has been proposed as a potential approach for the delivery of drugs to central nervous system. Ribavirin (RBV), an antiviral drug potentially useful treat viral infections both in humans and animals, previously demonstrated attain several brain compartments after nasal administration. Here, powder formulation form agglomerates comprising micronized RBV spray-dried microparticles containing excipients with absorption enhancing properties, i.e. mannitol, chitosan,...
Public awareness and discussion about animal experiments replacement methods has greatly increased in recent years. The term 'the Three Rs', which stands for the Replacement, Reduction Refinement of experiments, is inseparably linked this context. A common goal within Rs scientific community to develop predictive non-animal models better integrate all available data from vitro, silico omics technologies into regulatory decision-making processes regarding, example, toxicity chemicals, drugs...
Steroids, providing information regarding several biological patterns including stress and sexual behavior, have been investigated in different matrices laboratory mice. Data hair quantification, indicative of longer timespans when compared to blood saliva, are lacking. The aim the work was analyze hormonal profile male mice investigate potential relationships with age housing, as a tool for welfare assessment. Fifty-six adult C57BL/6J C57BL/6OlaHsd substrain were included study, housed...
Cephalopods are the first invertebrate class regulated by European Union (EU) under Directive 2010/63/EU on protection of animals used for scientific purposes, which requires prospective assessment severity procedures. To assist community in establishing classification cephalopods, we undertook a web-based survey EU cephalopod research as represented participants COoperation Science and Technology (COST) Action FA1301, Cephs InAction'. The consisted 50 scenarios covering range procedures...
On 1 January 2013, research using cephalopod molluscs, from hatchlings to adults, became regulated within Directive 2010/63/EU. There are significant difficulties in captive breeding the great majority of currently utilised species. Thus, scientific relies upon use wild-caught animals. Furthermore, live cephalopods shared and transported between different stakeholders laboratories across Europe other continents. Despite existing European national legislation, codes, guidelines reports...
Article 23(2) of the European Union Directive 2010/63/EU, which regulates welfare provisions for animals used scientific purposes, requires that staff involved in care and use purposes be adequately educated trained before they undertake any such work. However, nature extent training is not stipulated Directive. To facilitate Member States fulfilling their education obligations, Commission developed a common Education Training Framework, was endorsed by Competent Authorities. An &...
Since its publication, the 3Rs principle has provided a cornerstone for more ethical and humane biomedical regulatory research. In Europe, been incorporated into European Directive 63/2010/EU, with ultimate aim of fully replacing procedures on live animals scientific educational purposes as soon it is scientifically possible to do so. Thus, critical shift in discussion animal use research undergoing where satisfying "replacement" becoming defined rather than need. Centres have established...
The Italian Association for Laboratory Animal Sciences (AISAL) held its annual meeting in September 2022. main topic of the was section 'Quality Control Components Study' PREPARE guidelines. Among audience, all stakeholders AISAL were present: animal caretakers, technicians, facility managers, veterinarians, scientists, and welfare officers. One session also dedicated to round table on education training, with aim discuss legislative requirements as per Decree 5 August 2021.
In submitting conference proceedings to Biology and Life Sciences Forum, the volume editors of certify publisher that all abstracts published in this report have been subjected peer review administered by [...]
Environmental enrichment (EE) is a pivotal tool for creating ideal housing conditions that allow animals to fully display their ethograms. At the micro-environmental level, they should elicit cognitive and social responses increase physical activities. Hair steroids may be among best biomarkers evaluate effects of prolonged exposure different enrichments because are non-invasive provide information regarding longer period. This study aimed compare hair steroid profiles, specifically...
Betanodavirus is the causative agent of viral encephalopathy and retinopathy (VER). VER considered one most serious diseases in aquaculture causing enormous losses species high economic value as sea bass halibut (1). No commercial vaccine available efficacious countermeasures against are traditional prophylactic methods (2). Cinnamosma widely used medicine it’s active vitro several viruses (3). In this study we evaluated efficacy essential oil macrocarpa Betanodavirus. The cytotoxicity...