A5102991103- Animal testing and alternatives
- Birth, Development, and Health
- Heart Rate Variability and Autonomic Control
- Gestational Diabetes Research and Management
- Adipose Tissue and Metabolism
- Veterinary Pharmacology and Anesthesia
- Pregnancy and preeclampsia studies
- Atherosclerosis and Cardiovascular Diseases
- Lipoproteins and Cardiovascular Health
- Cardiovascular Disease and Adiposity
- Congenital heart defects research
- Animal Behavior and Welfare Studies
- Human-Animal Interaction Studies
- Meat and Animal Product Quality
- Intramuscular injections and effects
- Adipokines, Inflammation, and Metabolic Diseases
- Nuts composition and effects
- Peroxisome Proliferator-Activated Receptors
- Amyotrophic Lateral Sclerosis Research
- Effects and risks of endocrine disrupting chemicals
- Wnt/β-catenin signaling in development and cancer
- Health and Medical Research Impacts
- Fungal and yeast genetics research
- Glutathione Transferases and Polymorphisms
- Microbial infections and disease research
Hellenic Ministry of Rural Development and Food
2015-2024
National and Kapodistrian University of Athens
2008-2017
Athens State University
2005-2012
Laiko General Hospital of Athens
2007-2009
Hippocration General Hospital
2008
Athens Medical Center
2007
Abstract Aim To examine the relationship between sudomotor dysfunction and foot ulceration (FU) in patients with diabetes. Methods Ninety either Type 1 or 2 diabetes [30 without peripheral sensorimotor neuropathy (PN), 30 PN but FU FU] were recruited this cross‐sectional study. Assessment of was based on symptom score (NSS), disability (NDS) vibration perception threshold (VPT). Sudomotor assessed using sympathetic skin response (SSR). Cardiac autonomic nervous system activity by battery...
The Directive 2010/63/EU of the European Parliament and Council has been in force for more than a decade brought about significant improvements novel requirements welfare animals used scientific purposes, while safeguarding research integrity. sets clear provisions its scope, authorization procedures, animal bodies, national committees, cost/benefit analysis, severity classification, retrospective assessment, statistical reporting, among many others. From this perspective, indicative areas...
Evidence suggests that soluble CD40-ligand (sCD40L) is elevated in coronary artery disease (CAD) and released from activated platelets during the acute myocardial infarction (AMI). Although sCD40L part of immune response, mechanisms regulating its release different states remain unknown.This study enrolled 596 subjects: 201 patients with stable CAD, 109 AMI 286 healthy controls. Circulating levels sCD40L, interleukin-6 (IL-6), vascular cell adhesion molecule-a (sVCAM-1) intercellular...
The aim of the present study was to assess performance a new indicator test (NIT), based on measurement sweat production after exposure dermal foot perspiration, in diagnosis both peripheral sensorimotor polyneuropathy (PSN) and autonomic neuropathy patients with diabetes.One hundred seventeen diabetic were examined. PSN assessed using symptoms score, disability score vibration perception threshold. Cardiac (CAN) battery four classical standardized tests proposed by Ewing et al., Diabetes...
<h3>Background</h3> Exercise improves the clinical outcome of patients with coronary artery disease (CAD); however, ideal exercise duration for each patient remains unclear. <h3>Objective</h3> To investigate effects on arterial elastic properties and antioxidant/pro-oxidant mechanisms in CAD. <h3>Design, setting, patients, interventions</h3> Sixty male CAD were randomised into two groups, underwent 30 min or 60 a crossover design 2 weeks9 wash-out period. In all participants aortic radial...
Abstract Background Lipid-enriched diets and oxidative stress are risk factors for the development of atherosclerosis. The effects methanolic (ME) cyclohexane (CHE) extracts Pistacia vera nut, often included in Mediterranean diet, were studied rabbit model Methods results Twenty-four New Zealand White rabbits received atherogenic diet (Control Group), supplemented with ME (Group ME) or CHE CHE) 3 months. Previously, a GC-MS UHPLC LC-DAD-ESI(-)-HRMS/MS method developed to investigate...
Rabbits are widely used in biomedical research and especially as animal models atherosclerosis studies. Blood biochemistry is to monitor progression of disease, before final evaluation including pathology arteries organs. The aim the present study was assess consistency biochemical profile New Zealand White rabbits on standard diet from 3 6 months age, during which they often experimentally.Eight conventional male 3-month-old were used. samples taken at baseline, 1, 2 later. Plasma glucose,...
Increased density and distribution of wild boar populations are likely to promote interactions transmission certain pathogens, not only among but also from livestock or humans vice versa.The purpose this study was determine seroprevalence against seven selected pathogens in living four different areas Greece.In total, 359 serum samples were collected extensively farmed (Sus scrofa scrofa) originating distinct geographical throughout Greece April 2012 August 2013. Samples tested for...
Tail biting is both an important economic and a welfare problem. The primary preventive measure, almost on routine basis throughout Europe, remains tail docking following risk analysis. This study aimed to get insight the perceptions of Greek pig farmers towards docking, intervention measures, factors biting, as well opinions themes. Eighty-two answered questionnaire provided online in printed form. In case tail-biting outbreak, most measure removal bitten (victim), while feed quality, air...
Article 23(2) of the European Union Directive 2010/63/EU, which regulates welfare provisions for animals used scientific purposes, requires that staff involved in care and use purposes be adequately educated trained before they undertake any such work. However, nature extent training is not stipulated Directive. To facilitate Member States fulfilling their education obligations, Commission developed a common Education Training Framework, was endorsed by Competent Authorities. An &...
Background and aimsWe aimed to evaluate the impact of perinatal food manipulation on skeletal characteristics insulin levels Wistar rats at age 1 year.MethodsSixty-seven first-time pregnant were randomized, either normally fed (Control Diet, CD), food-restricted (FR), or fat-fed (FF), from 12th gestational day, gave birth 21st day pregnancy. Pups born FR-mothers divided into: fetal growth restricted (FGR) non-FGR, based their weight. Maternal continued through lactation period. Following...
This document provides assessment criteria for evaluation of each the Learning Outcomes Modules specified (in addition to Core Modules) those designing procedures and projects in Education Training Framework guidance by European Commission endorsed Member States Competent Authorities. Working Group was tasked produce these & Platform Laboratory Animal Science, which funded this aim. The address knowledge skills (including critical thinking) expected be acquired during education training...
This paper describes a set of principles for the conduct ethical review regarding experiments carried out on laboratory animals, which is important to be maintained from researchers throughout whole process, initial design experimental protocol up publication results in peer-reviewed journal. Animal use should justified after thorough examination existing validated alternative methods. The protocols will very soon become obligatory as revision European Directive 86/609/EEC, protection and...
This paper reviews the advantages of swine in relation to other animal models cardiopulmonary resuscitation referred literature. The causes cardiac arrest and difficulties raised during research humans are presented. All used this particular field discussed a detailed review is performed regarding major anatomical physiological similarities between man, as well experimental studies published international