A5100626573- Lung Cancer Diagnosis and Treatment
- Lung Cancer Treatments and Mutations
- Radiomics and Machine Learning in Medical Imaging
- MicroRNA in disease regulation
- Chronic Lymphocytic Leukemia Research
- Plant Stress Responses and Tolerance
- Acute Myeloid Leukemia Research
- Plant responses to water stress
- Chronic Myeloid Leukemia Treatments
- Plant Molecular Biology Research
- Anesthesia and Pain Management
- Hematological disorders and diagnostics
- Prostate Cancer Treatment and Research
- Endometrial and Cervical Cancer Treatments
- Lymphoma Diagnosis and Treatment
- Thermal Regulation in Medicine
- Veterinary Oncology Research
- Sympathectomy and Hyperhidrosis Treatments
- Enhanced Recovery After Surgery
- High-Voltage Power Transmission Systems
- Metabolomics and Mass Spectrometry Studies
- Circular RNAs in diseases
- Porphyrin Metabolism and Disorders
- Elevator Systems and Control
- Vacuum and Plasma Arcs
First Affiliated Hospital of Kunming Medical University
2019-2024
Kunming Medical University
2019-2024
Obstetrics and Gynecology Hospital of Fudan University
2015-2024
Shandong University
2024
Chinese People's Armed Police Force
2023
Shandong Management University
2023
JiangSu Armed Police General Hospital
2023
Xuzhou Medical College
2019-2022
Shanghai Clinical Research Center
2022
Jiangsu University
2022
BackgroundIntegrated 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) is widely performed in hilar and mediastinal lymph node (HMLN) staging of non-small cell lung cancer (NSCLC). However, the diagnostic efficiency PET/CT remains controversial. This retrospective study to evaluate accuracy characteristics false negatives positives improve specificity sensitivity. Methods219 NSCLC patients with systematic dissection or sampling underwent preoperative...
In chronic low back pain (CLBP), the relationship between spinal pathologies and paraspinal muscles fat infiltration remains unclear. This study aims to evaluate MRI findings morphology in CLBP patients by quantitative MRI.
Background Cervical cancer has the second-highest mortality rate among malignant tumors of female reproductive system. Immune checkpoint inhibitors such as programmed cell death protein 1 (PD-1) blockade are promising therapeutic agents, but their efficacy when combined with neoadjuvant chemotherapy (NACT) not been fully tested, and how they alter tumor microenvironment comprehensively elucidated. Methods In this study, we conducted single-cell RNA sequencing using 46,950 cells from nine...
: Drought is currently a global environmental problem, which inhibits plant growth and development seriously restricts crop yields. Many plants exposed to drought stress can generate memory, provides some advantages for resisting recurrent drought. DNA methylation mechanism involved in memory formation, many alter levels form memories; however, it remains unclear whether
Background Better selection of patients with intermediate and high-risk stage I endometrial carcinoma (EC) for lymphadenectomy has an important effect on the prognosis. Purpose To investigate role apparent diffusion coefficient (ADC) measurements in assessment EC based three risk categories. Material Methods We retrospectively studied 80 28 cervical cancer normal endometrium. 1.5-T conventional magnetic resonance imaging (MRI) diffusion-weighted (DWI) (b = 0, 1000 s/mm 2 ) were performed,...
Acute myeloid leukemia (AML) is a highly heterogeneous malignancy with various outcomes, and therefore needs better risk stratification tools to help select optimal therapeutic options. In this study, we identify miRNAs that could predict clinical outcome in AML population using TCGA dataset. We found MiR-363 novel prognostic factor patients undergoing chemotherapy. multivariable analyses, high miR-363 remained predictive for shorter OS (HR = 2.349, P 0.012) EFS 2.082, 0.001) independent of...
Epidural-related maternal fever (ERMF) heightens the risk of intrapartum fever, whereas effective prevention and treatment in clinical practice are currently lacking. Rapid sensitive screening tools for ERMF urgently needed to advance relevant research. In response this challenge, we devise craft porous Co
Background: This study investigated the influence of human cytochrome P450 2D6 (CYP2D6) gene polymorphism in gastric cancer (GC) patients to understand pharmacogenomic basis for patient response postoperative fentanyl analgesia. Methods: The prospective design contained 212 recovering from radical gastrectomy. Peripheral blood samples were collected after general anesthesia, and CYP2D6 genotypes analyzed using polymerase chain reaction–restriction fragment length (PCR-RFLP) method. After...
Objective: To explore the clinical features of patients with synchronous lymphoma and carcinoma. Methods: The data 17 Synchronous carcinoma from February 2012 to October 2017 were analyzed retrospectively. Results: Among lymphoma, 1 case HL, 2 cases B-NHL, 6 MZBL, 3 DLBCL, mantle cell (MCL) , NK/T- anaplastic large lymphoma(ALCL). In terms carcinoma, esophageal gastric colorectal 7 thyroid hepatocellular lung cancer. Up 15 received operation, some them combined chemotherapy, radiotherapy...
This retrospective study was conducted to investigate the impact of more extended mediastinal lymphadenectomy on outcome lung cancer patients treated with R0 resection.During investigation period, 325 cases were enlisted and 278 entered analysis. The divided into Control group (n=116) Research (n=162) according different extents lymph node clearance at time periods. Three major parameters retrospectively assessed compare quality surgical care: extent clearance, resection volume,...
Abstract Background We screened out several hypermethylated solute carrier (SLC) family genes in acute myeloid leukemia by reduced representation bisulfite sequencing. SLC22A3 encodes an organic cation transport protein, which is critical for drug transportation and cellular detoxification. significantly downregulated associated with tumor progression worse prognosis a variety of solid tumors. However, there are no data available regarding the role SLC22 AML. This study aimed to explore...
Objective To evaluate the efficacy of different doses dexmedetomidine for prevention shivering after combined spinal-epidural anesthesia in patients undergoing caesarean section. Methods A total 120 patients, ASA physical statusⅠ or Ⅱ, aged 20-40 yr, with body mass index≤35 kg/m2, scheduled elective section under anesthesia, were randomly divided into 4 groups (n=30 each) using a random number table: control group (group C) and 0.1, 0.3 0.5 μg/kg (D1, D2 D3 groups). Combined was...
To retrospectively analyze the safety and efficacy of low dose subcutaneous decitabine regimen in patients with acute myeloid leukemia (AML) intermediate- or higer-risk myelodysplastic syndrome (MDS). Of 6 AML cases, 2 achieved complete remission (CR), partial remission(PR), 1 stable disease(SD), progressive disease(PD). As to 8 MDS patients, one CR hematologic improvement (HI), case SD. Low could be an alternative choice older...
Objective: To detect the expression of CRLF2 in adult Ph negative acute B lymphocytic leukemia (B-ALL) newly diagnosed cases, and to investigate relationship between general clinical characteristics, efficacy prognosis. Methods: 103 cases B-ALL patients were investigated from Apr 2016 Dec 2017 Department Hematology, Henan Cancer Hospital. Bone marrow samples was used leukemic cells. The ≥20% defined as CRLF2-high group <20% CRLF2-low group. characteristics prognosis two groups compared....
Abstract Spontaneous tumors in pet dogs represent a valuable but undercharacterized cancer model. To better use this resource, we performed an initial global comparison between proliferative and invasive colorectal from 20 canine cases evaluated their molecular homology to human (CRC). We sequenced 15 intestinal samples for WGS 26 RNA-seq. investigated alterations the genome transcriptome, using state-of-the-art analysis tools. aslso microbiome, by mapping RNA-seq read pairs that could not...
Objective: To investigate the efficacy and prognosis of dynamic monitoring lymphocyte to monocyte ratio (LMR) in patients with diffuse large B-cell lymphoma (DLBCL). Methods: The clinical data 261 DLBCL Affiliated Cancer Hospital Zhengzhou University between March 2012 2018, were analyzed retrospectively. optimal cut-off values LMR was determined using receiver operating characteristic curve (ROC) method. Patients divided into low group high according value. changes before after treatment...