A5008069968- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- COVID-19 and healthcare impacts
- SARS-CoV-2 detection and testing
- COVID-19 and Mental Health
- Long-Term Effects of COVID-19
- Sleep and related disorders
- COVID-19 epidemiological studies
- Geriatric Care and Nursing Homes
- Lipoproteins and Cardiovascular Health
- Restless Legs Syndrome Research
- COVID-19 Impact on Reproduction
- Vitamin C and Antioxidants Research
- Sleep and Wakefulness Research
National Medical Center
2020-2022
Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-infected pneumonia emerged in Wuhan, China December 2019.In this retrospective multicenter study, we investigated the clinical course and outcomes of novel disease 2019 (COVID-19) from early cases Republic Korea.Methods: All confirmed by real time polymerase chain reaction were enrolled 1st to 28th patient nationwide.Clinical data collected analyzed for changes severity including laboratory, radiological, virologic...
Since severe acute respiratory syndrome-coronavirus-2 variant B.1.1.529 (omicron) was first reported to the World Health Organization on November 24, 2021, cases of omicron have been detected in more than 90 countries over last month. We investigated clinical and epidemiological characteristics 40 patients with who had isolated at National Medical Center South Korea during December 4-17, 2021. The median age 39.5 years. Twenty-two (55%) were women. Seventeen (42.5%) fully vaccinated, none...
The fatality rate of patients with coronavirus disease 2019 (COVID-19) varies among countries owing to demographics, patient comorbidities, surge capacity healthcare systems, and the quality medical care. We assessed clinical outcomes COVID-19 during first wave epidemic in Korea.
Although statins are widely prescribed lipid-lowering drugs, there concerns about the safety of their use in context coronavirus disease 2019 (COVID-19), since increase expression ACE2 (angiotensin-converting enzyme 2). This study aimed to disclose association between and 60-day COVID-19 mortality. Approach Results: All patients hospitalized with laboratory-confirmed were enrolled this from January 19 April 16, 2020, Korea. We evaluated COVID-19-related mortality overall nested 1:2...
Abstract Background The immunologic features of children with coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome 2 (SARS-CoV-2) are not clearly delineated. This study was conducted to evaluate SARS-CoV-2-specific antibody responses in COVID-19. Methods levels anti-spike (S) IgG, anti-SARS-CoV-2 and neutralizing (NAb) were measured during various time points <19 years age COVID-19 South Korea from February 2020 September 2020. Results One hundred sixty-five...
Concerns about the effectiveness of current vaccines against rapidly spreading severe acute respiratory syndrome-coronavirus-2 omicron (B.1.1.529) variant are increasing. This study aimed to assess neutralizing antibody activity wild-type (BetaCoV/Korea/KCDC03/2020), delta, and variants after full primary booster vaccinations with BNT162b2. A plaque reduction neutralization test was employed determine 50% dilution (ND
Background: Different hypotheses suggest a contradictory association of angiotensin receptor blockers (ARBs) or angiotensin-converting enzyme (ACE) inhibitors with potential adverse favorable effects in patients infected SARS-CoV-2. This study aimed to clarify if the use ARB and/or ACE inhibitor should be continued COVID-19 comorbidities.Methods: Data related 8,266 laboratory-confirmed SARS-CoV-2 infection through March 16, 2020, were retrieved. We evaluated ARBs and on SARS-CoV-2-related...
Although it is near concluded that renin-angiotensin system inhibitors do not have a harmful effect on coronavirus disease 2019 (COVID-19), there no report about whether angiotensin receptor blockers (ARBs) and angiotensin-converting enzyme (ACEIs) offer any protective role. This study aimed to compare the association of ARBs ACEIs with COVID-19-related mortality.
The third wave of the COVID-19 outbreak, in December 2020, overwhelmed Korean healthcare system. In particular, medical demand residents long-term care facilities, homeless shelters, group homes, and detention facilities surged. this study, we described experience from development operation an alternate facility (ACF) against pandemic. describe our implementation strategy, including layout plan, adequate staffing, admission criteria, patient flow. Using context existing guidelines literature...