A5078591815- Neural dynamics and brain function
- Neuroscience and Neural Engineering
- Photoreceptor and optogenetics research
- Neuroscience and Neuropharmacology Research
- EEG and Brain-Computer Interfaces
- Schizophrenia research and treatment
- Heart Rate Variability and Autonomic Control
- Neurological Disease Mechanisms and Treatments
- Natural Antidiabetic Agents Studies
- Pelvic and Acetabular Injuries
- Diabetic Foot Ulcer Assessment and Management
- Biological and pharmacological studies of plants
- Advanced Memory and Neural Computing
- Quinazolinone synthesis and applications
- Regulation of Appetite and Obesity
- Laser Applications in Dentistry and Medicine
- Surgical site infection prevention
- Functional Brain Connectivity Studies
- Adipokines, Inflammation, and Metabolic Diseases
- Molecular Communication and Nanonetworks
- Traditional and Medicinal Uses of Annonaceae
- Obstructive Sleep Apnea Research
- Natural product bioactivities and synthesis
- Electroconvulsive Therapy Studies
- Advanced Neuroimaging Techniques and Applications
Columbia University
2020-2025
Chengdu University of Traditional Chinese Medicine
2020-2024
Electronics and Telecommunications Research Institute
2023
New York University
2020
Ewha Womans University
2011-2014
Chenzhou First People's Hospital
2011-2014
Seoul National University Hospital
2009
Abstract Objective Temporal coordination between oscillations enables intercortical communication and is implicated in cognition. Focal epileptic activity can affect distributed neural networks interfere with these interactions. Refractory pediatric epilepsies are often accompanied by substantial cognitive comorbidity, but mechanisms predictors remain mostly unknown. Here, we investigate oscillatory coupling across large‐scale the developing brain. Methods We analyzed intracranial...
Epidermal electrophysiology is a non-invasive method used in research and clinical practices to study the electrical activity of brain, heart, nerves, muscles. However, electrode/tissue interlayer materials such as ionically conducting pastes can negatively affect recordings by introducing lateral electrode-to-electrode ionic crosstalk reducing spatial resolution. To overcome this issue, biocompatible, anisotropic-conducting composites (ACI) that establish an electrically anisotropic...
Chronic restraint stress (CRS) is a classic animal model of that can lead to various physiological and psychological dysfunctions, including systemic neuroinflammation memory deficits. Fresh Gastrodia elata Blume (FG), the unprocessed raw tuber Blume, has been reported alleviate symptoms headache, convulsions, neurodegenerative diseases, while protective effects FG on CRS-induced cognitive deficits remain unclear. This work aimed evaluate through multiplex behavior tests further explore...
Mature neural networks synchronize and integrate spatiotemporal activity patterns to support cognition. Emergence of these functions is believed be developmentally regulated, but the postnatal time course for perform complex computations remains unknown. We investigate progression large-scale synaptic cellular across development using high resolution in vivo electrophysiology immature mice. reveal that mature cortical processes emerge rapidly simultaneously after a discrete volatile...
<b><i>Background:</i></b> Patients with bipolar disorder are at a high risk for becoming obese. Adipokines associated depression and obesity via the inflammatory process. However, few studies have investigated associations between leptin, adiponectin resistin levels in patients disorder. We explored serum of mood metabolic status <b><i>Methods:</i></b> Body mass index (BMI) were assessed 94 Korean The Hamilton Rating Scale Depression-17 Young...
The current study aimed to investigate the possibility of rapid and accurate diagnoses Panic disorder (PD) Major depressive (MDD) using machine learning. support vector method was applied 2-channel EEG signals from frontal lobes (Fp1 Fp2) 149 participants classify PD MDD patients healthy individuals non-linear measures as features. We found significantly lower correlation dimension Lempel-Ziv complexity in left hemisphere compared subjects at rest. Most importantly, we obtained a 90%...
Objective: Due to its pleomorphic phenomenology, the clinical features of bipolar depression are difficult assess. The objective present study was therefore explore internal structure Bipolar Depression Rating Scale (BDRS) in terms phenomenological characteristics depression. Methods: Sixty patients with DSM-IV completed BDRS, and excitement subscales Positive Negative Syndrome (PANSS-D PANSS-E), 17-item Hamilton Scale, Montgomery–Äsberg Young Mania (YMRS), Drug-Induced Extrapyramidal...
High-density microelectrode arrays (MEAs) have opened new possibilities for systems neuroscience in human and non-human animals, but brain tissue motion relative to the array poses a challenge downstream analyses, particularly recordings. We introduce DREDge (Decentralized Registration of Electrophysiology Data), robust algorithm which is well suited registration noisy, nonstationary extracellular electrophysiology In addition estimating from spikes action potential (AP) frequency band,...
Current electrophysiological approaches can track the activity of many neurons, yet it is usually unknown which cell-types or brain areas are being recorded without further molecular histological analysis. Developing accurate and scalable algorithms for identifying cell-type region neurons thus crucial improving our understanding neural computation. In this work, we develop a multimodal contrastive learning approach data that be fine-tuned different downstream tasks, including inference...
Abstract Mature neural networks synchronize and integrate spatiotemporal activity patterns to support cognition. Emergence of these functions is believed be developmentally regulated, but the postnatal time course for perform complex computations remains unknown. We investigate progression large-scale synaptic cellular across development using high resolution in vivo electrophysiology immature mice. reveal that mature cortical processes emerge rapidly simultaneously after a discrete volatile...
Objective To analyze the clinical efficacy and safety of silkworm eroded dissolving method induced by micro-needle (the combined therapy traditional Chinese Western medicines including guiding,external application herbal membrane anti-scar cream) for treatment facial small area scar in early stage,and to explore a simple effective scar.Methods Total 100 patients with hyperplastic within 6 months after acute trauma healing were divided randomly into two groups 50 cases each.The group...
Objective To analyze the clinical efficacy and safety of combined therapy traditional Chinese Western medicine (heparin sodium cream massage, induced treatment by micro-needle, external application herbal membrane) micro-explosion method for facial pigmentation after trauma, to explore an effective skin-whitening anti-freckle. Methods A total 100 cases with on face were divided randomly into two groups 50 each: in group massaged heparin cream, needled skin spot densely micro-needle applied...
Objective To observe the clinical effect of Dengzhan Shengmai capsule in treatment lower extremity arteriosclerosis obliterans. Methods 60 patients were randomly divided into a control group and group, 30 for each group. The was treated with conventional western medicine alprostadil, while oral on basis 2 capsules time, three times day. two groups 14 days as cycle 4 cycles course. effects compared between these groups. Results The total effective rate 96.7%, that 80.0% (P<0.05)....