- Parasitic infections in humans and animals
- Archaeological and Historical Studies
- Literacy and Educational Practices
- Building materials and conservation
- Geological and Geophysical Studies Worldwide
- Vector-borne infectious diseases
- Spanish Linguistics and Language Studies
- Medieval Architecture and Archaeology
- Comparative Literary Analysis and Criticism
- Ancient Mediterranean Archaeology and History
- Trypanosoma species research and implications
- Libraries, Manuscripts, and Books
- Parasitic Infections and Diagnostics
- Congenital Anomalies and Fetal Surgery
- Educational Technology in Learning
- Mosquito-borne diseases and control
- Insect and Arachnid Ecology and Behavior
- Spanish Literature and Culture Studies
- Insect and Pesticide Research
- History of Education in Spain
- Plant and animal studies
- vaccines and immunoinformatics approaches
- Cultural and political discourse analysis
- Memory, violence, and history
- Medieval Iberian Studies
Instituto de Recursos Naturales y Agrobiología de Salamanca
2011-2024
Consejo Superior de Investigaciones Científicas
2022
National University of Distance Education
2021-2022
Universidad de Salamanca
2011
Institute of Geology and Mineral Exploration
2009
Ornithodoros moubata serves as primary vector of African swine fever and tick-borne human relapsing in Africa. Developing an effective vaccine targeting this argasid tick would significantly enhance disease control measures. To identify potential targets, the recently characterised sialome O. was analysed using a vaccinomics approach. This led to identification set salivary secreted proteins predicted be antigenic implicated regulation blood-feeding host immune defences. The objective study...
Cystic echinococcosis (CE) is one of the most widespread helminthic zoonoses and caused by tapeworm Echinococcus granulosus complex. CE diagnosis monitoring primarily rely on imaging techniques, complemented serology. This usually approached detection IgG antibodies against hydatid fluid (HF), but use this heterogeneous antigenic mixture results in a variable percentage false positive negative results, has shown to be useless for follow-up due long persistence anti-HF cured patients. To...
Cholesterol is a molecule vital for tick physiology, but ticks cannot synthesize it and rely on dietary cholesterol. Therefore, proteins involved in cholesterol absorption transport, such as the Niemann-Pick type C1 domain-containing (NPC1) proteins, are promising targets anti-tick vaccine development. The aim of this study was to assess structure, function, protective efficacy NPC1 orthologues identified previously midgut transcriptomes argasid Ornithodoros erraticus moubata. For purpose,...
Basic to intermediate high-K, high-Mg mantle-derived rocks occur throughout the Iberian Massif and are particularly important in Tormes Dome, where vaugnerites form several stocks small plutons. One of largest geochemically most variable among these plutons is Calzadilla pluton Dome that crystallized at 318 ± 1.4Ma (Bashkirian; U-Pb TIMS zircon). This age reveals vaugnerite was emplaced during transition from late D2 extensional deformation early D3 contractional (319 317Ma). Large-scale...
Human dirofilariasis cases have increased in Europe for the last few decades. We document an autochthonous case of infection subconjunctival space a 60-year-old Spanish man.The patient presented with pain his right eye, which was diagnosed as epi-scleritis. In spite treatment administered, no improvement reported. An external exam showed conjunctival congestion on temporal part eye bulbar conjunctiva. The anterior chamber flare or cells both eyes and dilated fundus normal. Nevertheless, long...
Cystic echinococcosis (CE) is a neglected zoonotic disease caused by Echinococcus granulosus sensu lato. Diagnosis and monitoring of CE rely primarily on imaging while serology used as confirmatory test. However, not always conclusive currently available serological assays have suboptimal sensitivity specificity, lack standardization, are useful for patients´ follow-up. Seroassays usually based hydatid fluid (HF), complex, variable antigenic mixture, cross-reactivity exists especially with...
La enseñanza del español-LE/L2 cuenta con una importante tradición de materiales didácticos. Su amplia oferta actual obras permite a aprendices, profesores y autoridades académicas satisfacer, entre otras, sus expectativas metodológicas. Todas persiguen, manera u otra, la adquisición-aprendizaje aspectos lingüísticos destrezas comunicativas que garanticen el dominio español. En valoración los manuales, metodología tiene especial importancia pues será decisiva para alcanzar propósitos...
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Ornithodoros moubata transmits African swine fever and human relapsing in Africa. The elimination of O. populations from anthropic environments is expected to improve the prevention control these diseases. Tick vaccines have emerged as a sustainable method for tick control, aquaporins (AQPs) are promising targets due their vital functions, immunogenicity ease access by neutralising host antibodies. This study aimed at systematic identification AQPs expressed (OmAQPs) characterisation vaccine...