A5056452600- Adipose Tissue and Metabolism
- Cardiovascular Function and Risk Factors
- Mitochondrial Function and Pathology
- Cardiovascular Disease and Adiposity
- Pain Mechanisms and Treatments
- Muscle Physiology and Disorders
- Natural product bioactivities and synthesis
- Medicinal Plant Pharmacodynamics Research
- Plant-Microbe Interactions and Immunity
- Neuropeptides and Animal Physiology
- Adipokines, Inflammation, and Metabolic Diseases
- Metabolism, Diabetes, and Cancer
- Pharmacological Effects of Natural Compounds
- Genomics and Phylogenetic Studies
- Autophagy in Disease and Therapy
- Exercise and Physiological Responses
- Mycotoxins in Agriculture and Food
- Dietary Effects on Health
- Plant Stress Responses and Tolerance
- Cannabis and Cannabinoid Research
- Cardiovascular and exercise physiology
- Liver Disease Diagnosis and Treatment
- Multiple Sclerosis Research Studies
- Traditional Chinese Medicine Analysis
- Ginseng Biological Effects and Applications
Shanghai University of Sport
2023-2025
Gannan Medical University
2021-2024
Hainan Medical University
2021-2022
The University of Texas Health Science Center at San Antonio
2019-2021
Shaanxi Normal University
2017-2021
First Affiliated Hospital of Dalian Medical University
2021
Changhai Hospital
2021
Second Military Medical University
2021
Dalian Medical University
2021
Hebei Normal University
2020
Fusarium graminearum is a notorious pathogen that causes head blight (FHB) in cereal crops. It produces secondary metabolites, such as deoxynivalenol, diminishing grain quality and leading to lesser crop yield. Many strategies have been developed combat this pathogenic fungus; however, considering the lack of resistant cultivars likelihood environmental hazards upon using chemical pesticides, efforts shifted toward biocontrol plant diseases, which sustainable eco-friendly approach. Fengycin,...
Abstract Exercise training mitigates cardiac pathological remodeling and dysfunction caused by myocardial infarction (MI), but its underlying cellular molecular mechanisms remain elusive. Our present study in an vivo rat model of MI determined the impact post‐MI exercise on fibrosis, mitochondrial biogenesis, antioxidant capacity, ventricular function. Adult male rats were randomized into: (a) Sedentary control group; (b) 4‐week treadmill (c) Sham surgery (d) group with permanent ligation...
Nearly 1400 Bacillus strains growing in the plant rhizosphere were sampled from different sites on Qinghai-Tibetan Plateau. Forty-five of isolates, selected due to their biocontrol activity, genome-sequenced and taxonomic identification revealed that they representatives subtilis species complex (20) cereus group (9). Majority remaining found closely related pumilus, but average nucleotide identity based BLAST electronic DNA/DNA hybridization values excluded closer identification. A total 45...
Background & AimsObesity promotes the development of nonalcoholic fatty liver diseases (NAFLDs), yet not all obese patients develop NAFLD. The underlying causes for this discrepancy remain elusive. LPGAT1 is an acyltransferase that catalyzes remodeling phosphatidylglycerol (PG), a mitochondrial phospholipid implicated in various metabolic diseases. Here, we investigated role regulating onset diet-induced obesity and its related hepatosteatosis because polymorphisms gene promoter were...
Cardiolipin is a mitochondrial signature phospholipid that plays pivotal role in maintaining cardiac health. A loss of tetralinoleoyl cardiolipin (TLCL), the predominant species healthy mammalian heart, implicated pathogenesis coronary heart disease (CHD) through poorly defined mechanisms. Here, we identified acyl-coenzyme A:lysocardiolipin acyltransferase-1 (ALCAT1) as missing link between hypoxia and CHD an animal model myocardial infarction (MI). ALCAT1 acyltransferase promotes...
Abstract Brassinosteroids (BRs) play important roles in regulating plant reproductive processes. BR signaling or biosynthesis null mutants do not produce seeds under natural conditions, but the molecular mechanism underlying this infertility is poorly understood. In study, we report that outer integument growth and embryo sac development were impaired ovules of Arabidopsis thaliana receptor mutant bri1‐116 . Gene expression RNA‐seq analyses showed INNER NO OUTER ( INO ), an essential...
Adipose tissue undergoes changes with aging, leading to increased adiposity, inflammatory cell infiltration, reduced angiogenesis, heightened oxidative stress, and alterations in its metabolic function. Regular exercise has been recognized as a powerful intervention that can positively influence adipose health mitigate the effects of aging. However, molecular mechanisms underlying benefits regular on aging function remain poorly understood. Adipokines released through play potential role...
Adipose tissue undergoes changes with aging, leading to increased adiposity, inflammatory cell infiltration, reduced angiogenesis, heightened oxidative stress, and alterations in its metabolic function. Regular exercise has been recognized as a powerful intervention that can positively influence adipose health mitigate the effects of aging. However, molecular mechanisms underlying benefits regular on aging function remain poorly understood. Adipokines released through play potential role...
Whipple's disease is a very rare systemic infectious disease, and few cases have been reported. However, it can be fatal if not diagnosed treated appropriately. The major clinical manifestations of this are usually digestive nervous system symptoms. majority patients male between 40 50 years old. Although respiratory symptoms rarely reported, they pose serious threat to the lives patients, especially when progress severe pneumonia. During admission hospital, Acinetobacter baumannii infection...
Neuropathic pain is still a serious and unsolved health problem. Activation of α7 nicotinic acetylcholine receptor (α7nAChR) known to modulate neuropathic by inhibiting microglial activation BDNF/TrkB/KCC2 signaling. We previously identified that trifluoro-icaritin (ICTF) has an attenuated effect on spared nerve injury (SNI)-induced pain, but its potential mechanisms remain unknown. Here, the pain-related behaviors were determined paw withdrawal threshold (PWT), CatWalk gait analysis,...
Obesity and type 2 diabetes mellitus (T2DM) are the leading causes of cardiovascular morbidity mortality. Although insulin resistance is believed to underlie these disorders, anecdotal evidence contradicts this common belief. Accordingly, obese patients with disease have better prognoses relative leaner same diagnoses, whereas treatment T2DM thiazolidinedione, one popular insulin-sensitizer drugs, significantly increases risk heart failure. Using mice skeletal musclespecific ablation...
The objective of this study was to report and discuss clinical analysis, including the diagnosis treatment 4 cases neuromyelitis optica spectrum disease (NMOSD) with area postrema syndrome (APS) as first symptom.Four patients intractable nausea, vomiting, confirmed NMOSD were included in final analysis. All these initially misdiagnosed mismanaged.Among patients, 3 admitted department gastroenterology at onset disease, 2 not correctly diagnosed treated promptly due misdiagnosis. Therefore,...
This study observes the morphological changes in enteric nervous system (ENS) - interstitial cells of Cajal (ICC) smooth muscle (SMC) network sphincter Oddi dysfunction (SOD) hypercholesterolemic rabbits following treatment with Shaoyao Gancao decoction (SGD), as well apoptosis ICC.In this study, 48 healthy adult New Zealand are randomly divided into three groups (n = 16 each group): control, model, and SGD groups. The rabbit model is established. Hematoxylin eosin staining, transmission...
Ischemic stroke caused by atherosclerosis (AS) poses a serious threat to human life expectancy and quality. With the development of genome-wide association studies, histone deacetylase 9 (HDAC9) expression atheromatous plaques with ischemic in large arteries has been revealed, but molecular mechanisms behind this phenomenon have not elucidated. In study, we explored effect HDAC9 on P38 mitogen activated protein kinase (P38 MAPK), classic cellular inflammation-related pathway, knocking down...
There is a notable correlation between mitochondrial homeostasis and metabolic disruption. In this review, we report that obesity-induced disruption of adversely affects lipid metabolism, adipocyte differentiation, oxidative capacity, inflammation, insulin sensitivity, thermogenesis in thermogenic fat. Elevating fat emerges as promising avenue for developing treatments diseases, including enhanced function, mitophagy, uncoupling, biogenesis. The exerkines (e.g., myokines, adipokines,...