- Renal Transplantation Outcomes and Treatments
- Organ Donation and Transplantation
- Organ Transplantation Techniques and Outcomes
- Renal and Vascular Pathologies
- Transplantation: Methods and Outcomes
- Organ and Tissue Transplantation Research
- Palliative Care and End-of-Life Issues
- Polyomavirus and related diseases
- Pediatric Urology and Nephrology Studies
- Infectious Aortic and Vascular Conditions
- Parvovirus B19 Infection Studies
- Diabetes Treatment and Management
- Neurological Complications and Syndromes
- Systemic Sclerosis and Related Diseases
- Vascular Procedures and Complications
- Blood transfusion and management
- Grief, Bereavement, and Mental Health
- Hepatitis C virus research
- Cervical Cancer and HPV Research
- Acute Kidney Injury Research
- Diphtheria, Corynebacterium, and Tetanus
- Central Venous Catheters and Hemodialysis
- Urological Disorders and Treatments
- Liver Disease and Transplantation
Riga Stradiņš University
2011-2024
Pauls Stradiņš Clinical University Hospital
2010-2024
Latvian Biomedical Research and Study Centre
2006-2023
Public Health Service of Amsterdam
2023
Amsterdam University Medical Centers
2023
University of Amsterdam
2023
University of Latvia
2012
Armed Forces Medical College
2012
Objective: The creation of an arteriovenous fistula (AVF) is considered the most effective hemodialysis (HD) vascular access. For patients who are not suitable for AVF, grafts (AVGs) best access option chronic HD. However, conventional AVGs prone to intimal hyperplasia, stenosis, thrombosis, and infection. Xeltis has developed AVG as a potential alternative currently available based on concept endogenous tissue restoration. results first 6-month follow-up presented here. Methods: aXess...
ABSTRACT Background Large international differences exist in kidney transplantation (KT) rates. We aimed to investigate which factors may explain the total, deceased donor and living KT rates over last decade. Methods experts from 39 European countries completed Kidney Transplantation Rate Survey on measures barriers their potential effect rate country. In analyses, were divided into low, middle high based at start of study period 2010. Results Experts low reported more frequently that they...
The primary aim of this study was to describe regulations and practices concerning the family approach discuss donation, specifically after neurological determination death, one most challenging steps in donation pathway. A secondary objective assess impact legislation on consent rates for organ donation. Council Europe surveyed 39 member states about national regulations, practices, rates; 34 replied. Opt-out is present 19, opt-in 9 a mixed system six countries. An opt-out register kept by...
Introduction Donation after circulatory death (DCD) has become an accepted practice in many countries and remains a focus of intense interest the transplant community due to its potential increase donor pool. In 2011, European Committee on Organ Transplantation (CD-P-TO) Council Europe (COE) published study situation DCD Europe. Since then, scene enormously changed, with more initiating or developing programmes practices evolving as new evidence becomes available. The aim present is provide...
Abstract Background and Aims Kidney transplantation is a treatment for many patients with end stage renal disease leading to increased quality of life. In last decades results in kidney have been improving, but allograft rejection remains an important clinical problem. Graft biopsy the gold standard assess cause transplant status. This study aimed determine histopathological characteristics, short-term outcomes biopsy-proved graft Latvia. Method this retrospective observational all biopsies...
Introduction: Latvia faces a challenging shortage of available kidney donors, leading to significant mismatch between demand for transplantation and supply. Although older adult donors require thorough pre-donation workup rule out medical comorbidities, it offers hope potential candidates. Case Presentation: This case study presents the unique scenario an 87-year-old living donor, where individualized decision-making resulted in outstanding outcomes both donor recipient. Conclusions: The...
Abstract Kidney transplantation has become a preferred treatment for many patients with end-stage renal disease, leading to increased quality of life. In recent decades, results in kidney have been improving, but allograft rejection remains an important clinical problem. This retrospective study reviewed all biopsies performed at Pauls Stradiņš Clinical University Hospital from January 2014 December 2022, the aim determine and histopathological characteristics, treatment, short-term outcomes...
The article presents an overview of literature related to two topical issues in modern medicine: transplantation and biomarkers. There have been advances made the use immunoenzymometric immunoadsorption assays organ clinics for evaluating different situations. However, these methods fail solve more complex ambiguous problems: tolerance, personification treatment, etc. In this regard, first results prospective studies using OMICS genomics proteinomics, relation notion transplantomics, are presented
Summary Introduction. During the last years percentage of elderly organ donors has increased significantly and may impact results kidney transpalantations (KT). Aim Study. Was to analyse transplantation from donors. Materials methods. In this study we analysed all consecutive KT deceased (DD) performed in a single center during period 01.01.2004 till 31.12.2007, with following exclusion criteria: unavailability 5-year follow-up DD aged 50 59 years. result population consisted 193 recipients,...
Summary Introduction. During the previous years number of organ transplantations from elderly donors increased, and lack young leads to necessity allocate organs into recipients. Aim Study. Was analyse results “old-to-young” allocation. Material methods. This retrospective study analysed all consecutive deceased donor kidney (DDKT) performed in one transplant centre during period 01.01.2004 till 31.12.2007. Patients were selected based on availability 5-year follow-up age < 50 (158 DDKT)....
A growing lack of donor organs has caused extension criteria for deceased donation. Therefore, elderly donors and with increased serum creatinine levels, as well after cardiocirculatory death, have become used more frequently. The examination such is strongly limited due to the time, determination quality still based on clinical laboratory screening data donors. Implementation new methods required determine functional condition accurately, which would allow correct selection This...
Delayed renal graft function (DGF) is a frequent complication with negative impact on the course of early post-transplantation period. The data concerning late results are contradictory. This study describes 5-year follow-up 248 recipients after deceased donor transplantation. All patients were divided into two groups: delayed (DGF, n = 53) and immediate function, considered as control group (IGF, 195). We evaluated factors that associated development DGF its survival recipient, frequency...