A5022995774- Renal Transplantation Outcomes and Treatments
- Dialysis and Renal Disease Management
- Parathyroid Disorders and Treatments
- Central Venous Catheters and Hemodialysis
- Organ Donation and Transplantation
- Organ Transplantation Techniques and Outcomes
- Cytomegalovirus and herpesvirus research
- Pharmacological Effects and Toxicity Studies
- Renal and Vascular Pathologies
- Hepatitis C virus research
- SARS-CoV-2 and COVID-19 Research
- Hepatitis B Virus Studies
- Viral-associated cancers and disorders
- Vitamin D Research Studies
- COVID-19 Clinical Research Studies
- HIV/AIDS drug development and treatment
- Herpesvirus Infections and Treatments
- Renal Diseases and Glomerulopathies
- Vascular Procedures and Complications
- Liver Disease Diagnosis and Treatment
- Bone health and osteoporosis research
- Systemic Sclerosis and Related Diseases
- Erythropoietin and Anemia Treatment
- Hemoglobinopathies and Related Disorders
- Polyomavirus and related diseases
Administração Regional de Saúde de Lisboa e Vale do Tejo
2024-2025
Universidade Nova de Lisboa
2023-2025
University of Lisbon
2025
Hospital Curry Cabral
2023-2024
Instituto Nacional de Salud Pública
2024
Saarland University
2020-2023
Centro Hospitalar de Lisboa Central
2023
Hospital de Santa Cruz
2012-2022
Hospital Vila Franca de Xira
2005-2022
Pediatric Nephrology of Alabama
2021-2022
Vitamin D deficiency is highly prevalent in chronic kidney disease. The aim of this study was to evaluate the effects oral cholecalciferol supplementation on mineral metabolism, inflammation, and cardiac dimension parameters long-term hemodialysis (HD) patients.This 1-year prospective included 158 HD patients. Serum levels 25-hydroxyvitamin [25(OH)D], 1,25-dihydroxyvitamin [1,25(OH)(2)D], intact parathyroid hormone, plasma brain natriuretic peptide as well circulating bone metabolism...
Kidney transplant recipients are a subgroup of patients at higher risk critical forms Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection and poor outcomes due to immunosuppression treatment. Herein, we present data from single center cohort kidney with SARS-CoV-2 infection.In prospective study, baseline characteristics, clinical features, antiviral management were compared between outpatients hospitalized patients, during one-year period.Seventy-seven analyzed, including...
Decreased vitamin D serum levels have been recently related to arterial stiffening and vascular calcifications in haemodialysis (HD) patients, but the pathophysiology of this association is not yet clear. The aim study was evaluate relationship between calcifications, cardiovascular risk factors [including brain natriuretic peptide (BNP), pulse pressure (PP) left ventricular mass index] 25-hydroxyvitamin D3 (25(OH)D3) 1,25-dihydroxyvitamin [1,25(OH)(2)D3] levels.We performed a...
<b><i>Background:</i></b> Hypomagnesaemia is a cardiovascular (CV) risk factor in the general population. The aim of this study was to evaluate relationship between pre-dialysis magnesium (Mg) and CV markers, [including pulse pressure (PP), left ventricular mass index (LVMI) vascular calcifications (VC)], mortality haemodialysis (HD) patients. <b><i>Methods:</i></b> We performed 48-month prospective 206 patients under pre-dilution...
Introdução: As biópsias de tempo zero [time-zero biopsies (TzB)] fornecem informações sobre lesões provenientes do doador, mas seu valor preditivo para os resultados a longo prazo permanece incerto. O objetivo deste trabalho foi identificar fatores clínicos e histológicos das TzB doadores falecidos que influenciam taxa filtração glomerular (TFG) aos 3 5 anos pós-transplante renal. Métodos: Analisámos retrospectivamente realizadas janeiro 2015 agosto 2019. Foram excluídas 19 por óbito...
Background: Time-zero biopsies (TzB) provide insights into donor-derived lesions, but their predictive value for long-term outcomes remains uncertain. We aimed to identify clinical and histological factors from TzB of deceased donors influencing glomerular filtration rate (GFR) at 3- 5-year post-transplantation. Methods: retrospectively analyzed performed January 2015 August 2019. Nineteen were excluded due recipient death before 3 years. examined donor recipient-related characteristics...
Dialysate leakage is a complication of peritoneal dialysis with 5% incidence rate. Late leaks are rare, and symptoms subtle, as fluid loss occurs most often through abdominal wall defects. An 83-year-old diabetic woman was started on automated one month after catheter placement. Three years later, the patient complained tiredness, peripheral edema, pressure. Inspection showed local erythema orange-peel skin. A computed tomography scan periumbilical drainage, suggesting leak. The referred for...
ABSTRACT Background Large international differences exist in kidney transplantation (KT) rates. We aimed to investigate which factors may explain the total, deceased donor and living KT rates over last decade. Methods experts from 39 European countries completed Kidney Transplantation Rate Survey on measures barriers their potential effect rate country. In analyses, were divided into low, middle high based at start of study period 2010. Results Experts low reported more frequently that they...
Abstract Background Previous contact with Hepatitis B virus (HBV) is common in patients undergoing hemodialysis. Literature has shown conflicting results on the risk of HBV reactivation kidney transplant (KT) recipients serologic evidence past infection. Methods We reviewed 631 consecutive KT and selected 70 simultaneously HBsAg negative anti‐HBc positive before KT, regardless hepatitis surface antibody (anti‐HBs) status. Demographic characteristics, coinfection other viruses, presence a...
<b><i>Background/Aim:</i></b> Calcium acetate/magnesium carbonate (CaMg) is a recent phosphate binder that has been shown to have protective cardiovascular (CV) effects in animal models. The aim of this study was evaluate the relationship between CaMg therapy and CV risk markers like pulse pressure (PP), left ventricular mass index (LVMI) valvular calcifications compared sevelamer or no (NPB) chronic hemodialysis (HD) patients....
Bone alkaline phosphatase (bAP) is known to be an important biochemical marker of bone formation. Through the present study, we intended find out whether there any advantage in bAP determination, as a routine marker, besides intact parathyroid hormone (iPTH) hemodialysis patients.In population 140 patients, and iPTH were determined on four quarterly consecutive occasions. According values (pg/ml) (ng/ml), patients divided into groups: group I: > 200 20, II: < III: 20 IV: 20. Patients with...
After a kidney transplant, it is unknown whether the maintenance of functioning hemodialysis arteriovenous access could have deleterious effects on renal grafts. We hypothesize that maintaining an can deviate significant proportion cardiac output from graft. The aim this study was to investigate temporary closure lead increase in graft perfusion.We conducted 17 kidney-transplanted patients with access. evaluated, at baseline and 30 s after compression (access flow occlusion), hemodynamic...
We report the case of an isolated JC virus (JCV) infection, without co-infection by polyoma BK (BKV), associated with nephropathy 4 years after kidney transplantation. Clinical suspicion followed observation a decrease in estimated glomerular filtration rate (eGFR) and renal allograft biopsy revealing polyomavirus-associated tubulointerstitial nephritis positivity for SV40. An in-house real-time polymerase chain reaction assay, targeting presence JCV absence BKV tissue, confirmed diagnosis....
A 56-year-old African patient received a kidney from deceased donor with 4 HLA mismatches in April 2013. He immunosuppression basiliximab, tacrolimus, mycophenolate mofetil, and prednisone. Immediate diuresis good allograft function were soon observed. Six months later, the serum creatinine level increased to 2.6 mg/dL. renal biopsy revealed interstitial fibrosis tubular atrophy grade II. Toxicity of calcineurin inhibitor was assumed and, after switch for everolimus, improved. However, since...
Low levels of 25-hydroxyvitamin D [25(OH)D] are frequent in chronic kidney disease and associated with adverse outcomes. The aim this 5-year prospective study was to evaluate the effects cholecalciferol supplementation on mineral metabolism, inflammation cardiac parameters hemodialysis (HD) patients.The included 97 patients. Cholecalciferol given after HD according 25(OH)D baseline measured twice (end winter summer). levels, circulating bone parameters, brain natriuretic peptide (BNP), pulse...