Franz Immer
- Organ Donation and Transplantation
- Organ Transplantation Techniques and Outcomes
- Renal Transplantation Outcomes and Treatments
- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Palliative Care and End-of-Life Issues
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Transplantation: Methods and Outcomes
- Liver Disease and Transplantation
- Mechanical Circulatory Support Devices
- Congenital Heart Disease Studies
- Medical and Health Sciences Research
- Liver Disease Diagnosis and Treatment
- Infective Endocarditis Diagnosis and Management
- Grief, Bereavement, and Mental Health
- SARS-CoV-2 and COVID-19 Research
- Organ and Tissue Transplantation Research
- Acute Myocardial Infarction Research
- Hepatitis C virus research
- Pneumocystis jirovecii pneumonia detection and treatment
- COVID-19 Clinical Research Studies
- Cytomegalovirus and herpesvirus research
- Cardiac Structural Anomalies and Repair
Swiss National Science Foundation
2014-2025
University Hospital of Geneva
2024
University of Bern
2001-2023
Swiss HIV Cohort Study
2023
Hôpital Beau-Séjour
2023
Financial Research (Hungary)
2023
University of Milano-Bicocca
2023
University Hospital of Basel
2000-2022
Swissmedic
2022
University Hospital of Bern
1999-2017
Abstract Background The burden and timeline of posttransplant infections are not comprehensively documented in the current era immunosuppression prophylaxis. Methods In this prospective study nested within Swiss Transplant Cohort Study (STCS), all clinically relevant were identified by transplant–infectious diseases physicians persons receiving solid organ transplant (SOT) between May 2008 December 2014 with ≥12 months follow-up. Results Among 3541 SOT recipients, 2761 (1612 kidney, 577...
Liver graft utilization rates are a hot topic due to the worldwide organ shortage and increasing number of transplant candidates on waiting lists. perfusion techniques have been introduced in several countries, may help increase supply, as they potentially enable assessment livers before use.Liver offers were counted from donation after circulatory death (DCD) donors (Maastricht type III) arising during past decade eight including Belgium, France, Italy, Netherlands, Spain, Switzerland, UK,...
Vaccine responses are decreased in solid organ transplant (SOT) recipients, and given the complexity of implementation, vaccination programs may be suboptimal. The actual burden vaccine-preventable infections (VPIs) among SOT recipients remains unclear.To assess incidence rate VPIs to evaluate whether at increased risk for specific compared with general population.This nationwide cohort study used data from Swiss Transplant Cohort Study on individuals who underwent May 2008 June 2019...
BackgroundMinimal extracorporeal circulation (MECC) is a promising perfusion technology, taking the advantage of an ECC while having significantly reduced priming volume. We analyzed actual possible benefits using MECC in patients undergoing CABG procedures and compared results with conventional (CECC).MethodsOne thousand fifty-three consecutive underwent surgery technique. Subgroup analyses focused on perioperative myocardial markers (cardiac troponin I [cTnI]), incidence atrial...
To report on a concept of liver assessment during ex situ hypothermic oxygenated perfusion (HOPE) and its significant impact utilization.
Abstract Background The use of assays detecting cytomegalovirus (CMV)–specific T cell–mediated immunity may individualize the duration antiviral prophylaxis after transplantation. Methods In this randomized trial, kidney and liver transplant recipients from 6 centers in Switzerland were enrolled if they CMV-seronegative with seropositive donors or CMV-seropositive receiving antithymocyte globulins. Patients to a based on immune monitoring (intervention) fixed (control). control group planned...
There is limited information on the effects of statins outcomes liver transplantation (LT), regarding either their use by LT recipients or donors.
There are limited contemporary data on the epidemiology and outcomes of bacteremia in solid organ transplant recipients (SOTr).Using Swiss Transplant Cohort Study registry from 2008 to 2019, we performed a retrospective nested multicenter cohort study describe SOTr during first year post-transplant.Of 4383 patients, 415 (9.5%) with 557 cases due 627 pathogens were identified. One-year incidence was 9.5%, 12.8%, 11.4%, 9.8%, 8.3%, 5.9% for all, heart, liver, lung, kidney, kidney-pancreas...
The Swiss allocation system for kidney transplantation has evolved over time to balance medical urgency, immunological compatibility, and waiting time. Since the introduction of law in 2007, which imposed organ on a national level, algorithm been optimized. Initially based time, HLA crossmatch performed by cell complement-dependent cytotoxicity techniques, moved 2012 score including anti-HLA antibodies detected Luminex® technology, virtual crossmatch. In 2015, was optimized impact preemptive...
Background— Since 1994 patients with acute aortic dissection type A (AADA) are followed-up in our outpatient clinic. Early diagnosis of secondary dilatation the diseased aorta is crucial to reduce late mortality these patients. Aim present study asses impact a large volume false lumen downstream on dilatation. Methods and Results— 134 264 who underwent surgery for AADA (between January June 2003) at clinic since 1994. 84 (62.7%) fulfilled inclusion criteria. Areas true lumens were analyzed...
Abstract In cystic fibrosis (CF) patients, chronic airway infection by Pseudomonas leads to progressive lung destruction ultimately requiring transplantation (LT). Following LT, CF-adapted strains, potentially originating from the sinuses, may seed allograft leading infections and reduced survival. We investigated whether populations invade donor microbiota adapt non-CF allograft. collected sequential isolates samples a CF-lung transplant recipient during two years, followed dynamics of...
Background The donation rate (DR) per million population is not ideal for an efficiency comparison of national deceased organ programs. DR does account variabilities in the potential which mainly depends on fatalities from causes leading to brain death. In this study, activity was put into relation mortality selected causes. Based that metric, study assesses different Methods This a retrospective analysis 2001 2015 and registry data. Included are 27 Council Europe countries, as well United...