A5028016782- Ovarian cancer diagnosis and treatment
- PARP inhibition in cancer therapy
- Colorectal Cancer Screening and Detection
- Meta-analysis and systematic reviews
- Olfactory and Sensory Function Studies
- Cancer-related cognitive impairment studies
- Alzheimer's disease research and treatments
- Ethics in Clinical Research
- Pesticide and Herbicide Environmental Studies
- Infant Health and Development
- Pharmaceutical industry and healthcare
- Endometrial and Cervical Cancer Treatments
- Plant-based Medicinal Research
- Treatment of Major Depression
- Pain Management and Placebo Effect
- Cancer therapeutics and mechanisms
- scientometrics and bibliometrics research
- Chemotherapy-related skin toxicity
- Health Systems, Economic Evaluations, Quality of Life
- Lung Cancer Research Studies
- Occupational and environmental lung diseases
- Inflammatory Biomarkers in Disease Prognosis
- Helicobacter pylori-related gastroenterology studies
- Aortic Disease and Treatment Approaches
- Global Cancer Incidence and Screening
University of Oxford
2020-2024
Nuffield Orthopaedic Centre
2020-2024
Careers Europe
2021
Shahid Beheshti University of Medical Sciences
2015-2016
The Southwest Oncology Group (SWOG) has conducted a phase II study to explore the efficacy and toxicity of initial, concurrent use radiation therapy with cisplatin, etoposide (VP-16), vincristine in limited-stage small-cell carcinoma lung. Two courses VP-16, chemotherapy were given radiotherapy (XRT) primary tumor total dose 4,500 cGy. Elective brain XRT was all patients third course cisplatin/VP-16 therapy. Consolidation consisting vincristine, methotrexate, VP-16 alternating Adriamycin...
Background We previously found that 25% of 1,017 randomized clinical trials (RCTs) approved between 2000 and 2003 were discontinued prematurely, 44% remained unpublished at a median 12 years follow-up. aimed to assess decade later (1) whether rates completion publication have increased; (2) the extent which nonpublished RCTs can be identified in trial registries; (3) association reporting quality protocols premature discontinuation or nonpublication RCTs. Methods findings included 326 RCT...
Grâce aux efforts du programme d'éradication paludisme en Tunisie, le dernier cas autochtone date de 1979. Cependant, des importés sont plus rapportés ces dernières années. Notre objectif était décrire les caractéristiques épidémiologiques notifiés 2018 à 2022. MéTHODES: Nous avons analysé données surveillance maladies déclaration obligatoire Tous provenant laboratoires publics et privés ainsi que d'établissements santé ont été travers formulaires collecte données. Les patients testés par...
Abstract Background Liraglutide is a glucagon‐like peptide‐1 (GLP‐1) analogue licensed for the treatment of type 2 diabetes. Preclinical evidence in transgenic models Alzheimer’s disease suggests that liraglutide exerts neuroprotective effects by reducing amyloid oligomers, normalising synaptic plasticity and cerebral glucose uptake, increasing proliferation neuronal progenitor cells. Methods ELAD 12‐month, multi‐centre, randomised, double‐blind, placebo‐controlled, phase IIb trial...
Abstract Background Preclinical evidence in transgenic models of Alzheimer’s disease (AD) suggests that liraglutide, a GLP1 analogue, exerts neuroprotective effects by reducing amyloid oligomers, normalising synaptic plasticity and insulin resistance, increasing the proliferation neuronal progenitor cells. ELAD is 12‐month, multi‐centre, randomised, double‐blind, placebo‐controlled, phase IIb trial liraglutide participants with mild to moderate AD conducted at 24 centres UK. Method As part...
Introduction Patients relapsing within 12 months of platinum-based chemotherapy usually have a poorer response to subsequent treatments. To date, extensive research into the mechanism resistance platinum agents in treatment ovarian cancer has not resulted improved responses or longer survival. Further experimental work and clinical trials with novel are therefore justified address this unmet need. ovarian, fallopian tube primary peritoneal that relapsed will be randomised stratification for...
Colorectal cancer is the second most common cause of death with half a million deaths per year. Incidence and mortality rates have demonstrated notable changes in Asian African countries during last few decades. In this study, we first aimed to determine trend colorectal rate each Institute for Health Metrics Evaluation (IHME) region, then re-classify them find more homogenous classes.Our study population consisted 52 Asia North Africa six IHME pre-defined regions both genders...
Availability of randomized controlled trial (RCT) protocols is essential for the interpretation results and research transparency.In this study, we determined availability RCT approved in Switzerland, Canada, Germany, United Kingdom 2012. For these RCTs, searched PubMed, Google Scholar, Scopus, registries publicly available corresponding full-text publications results. We proportion RCTs with (1) protocols, (2) citing protocol, (3) providing a link to protocol. A multivariable logistic...
Background: Stomach cancer is the fifth most common and third leading cause of death among cancers throughout world. Therefore, stomach outcomes can affect health systems at national international levels. Although mortality incidence rates have decreased in developed countries, these indicators a raising trend East Asian developing particularity Iran. In this study, we aimed to determine time age-standardized different districts Iran from 2000 2010. Materials Methods: Cases were registered...
Effect of Coriander Fruit on Clinical Course Migraine Patients: A Comparison between Random and Transition Models
Introduction About 60 % of the subjects with a first episode major depression will present second lifetime. Thus, it is important to determine risk factors recurrence. Aims To identify depressive Methods It retrospective study conducted in university hospital Mahdia including 150 patients hospitalized psychiatric ward for disorder according DSM-IV-TR. Data were collected using questionnaire 89 items. Statistical analysis was done Kaplan-Meier method. The Cox test used check recurrence...
Abstract Introduction Tuberculosis (TB) is a major cause of morbidity and mortality worldwide. In Tunisia, where TB remains endemic, the national control program ensures free vaccination, outpatient treatment in addition to early detection cases directly observed short course. However, available data on these activities outcomes are limited. The objective this study was describe evolution management indicators from 2018 2021. Methods We analyzed collected part epidemiological investigations...
Le traitement de choix du cancer bronchique non a petites cellules est la chirurgie. Cependant, seuls 25 30% des patients sont operables. Dans les formes disseminees (50% cas), chimiotherapie le principal palliatif. Actuellement, nouvelles associations font reconsiderer classique chimio-resistance ces tumeurs. localement avancees (25%) cas, l’association radiochimiotherapie concomitante represente un standard. De nouveaux produits tels inhibiteurs l’angiogenese pourront dans l’avenir etre...