A5018067783- Genetic Mapping and Diversity in Plants and Animals
- Plant-Microbe Interactions and Immunity
- Genetic diversity and population structure
- Gut microbiota and health
- Genetic and phenotypic traits in livestock
- Legume Nitrogen Fixing Symbiosis
- Genomics and Phylogenetic Studies
- Genetics and Plant Breeding
- Mycorrhizal Fungi and Plant Interactions
- Plant Pathogens and Fungal Diseases
- Plant Molecular Biology Research
- Ecology and Vegetation Dynamics Studies
- Plant nutrient uptake and metabolism
- Evolution and Genetic Dynamics
- Genetic and Environmental Crop Studies
- Microbial Community Ecology and Physiology
- Plant Virus Research Studies
- Probiotics and Fermented Foods
- Plant Disease Resistance and Genetics
- Digestive system and related health
- Health, Environment, Cognitive Aging
- Mercury impact and mitigation studies
- Plant Pathogens and Resistance
- Nematode management and characterization studies
- Wildlife Ecology and Conservation
Research Institute of Organic Agriculture
2025
Forschungsinstitut für biologischen Landbau
2024
Forschungsinstitut für Biologischen Landbau
2024
University of Zurich
2016-2021
King's College London
2020
Erasmus MC
2020
Imperial College London
2020
Vrije Universiteit Amsterdam
2020
Gregor Mendel Institute of Molecular Plant Biology
2012-2016
Austrian Academy of Sciences
2012-2016
Diverse communities of bacteria inhabit plant leaves and roots those play a crucial role for health growth. Arabidopsis thaliana is an important model to study pathogen interactions, but little known about its associated bacterial community under natural conditions. We used 454 pyrosequencing characterize the with wild A. collected at 4 sites; we further compared on outside plants in endophytic compartments. found that most heavily sequenced are related culturable species. Proteobacteria,...
Understanding the genetic bases and modes of adaptation to current climatic conditions is essential accurately predict responses future environmental change. We conducted a genome-wide scan identify climate-adaptive loci pathways in plant Arabidopsis thaliana. Amino acid-changing variants were significantly enriched among strongly correlated with climate, suggesting that our effectively detects adaptive alleles. Moreover, from results, we successfully predicted relative fitness set...
There is currently tremendous interest in the possibility of using genome-wide association mapping to identify genes responsible for natural variation, particularly human disease susceptibility. The model plant Arabidopsis thaliana many ways an ideal candidate such studies, because it a highly selfing hermaphrodite. As result, species largely exists as collection naturally occurring inbred lines, or accessions, which can be genotyped once and phenotyped repeatedly. Furthermore, linkage...
The population structure of an organism reflects its evolutionary history and influences trajectory. It constrains the combination genetic diversity reveals patterns past gene flow. Understanding it is a prerequisite for detecting genomic regions under selection, predicting effect disturbances, or modeling This paper examines detailed global Arabidopsis thaliana. Using set 5,707 plants collected from around globe genotyped at 149 SNPs, we show that while A. thaliana as species...
Roots provide plants mineral nutrients and stability in soil; while doing so, they come into contact with diverse soil microbes that affect plant health productivity. Despite their ecological agricultural relevance, the factors shape root microbiome remain poorly understood. We grew a worldwide panel of replicated Arabidopsis thaliana accessions outdoors over winter to characterize root-microbial communities. Although studies tend focus on bacteria, we found evidence fungi have strong...
Abstract Arabidopsis thaliana is an important model organism for understanding the genetics and molecular biology of plants. Its highly selfing nature, small size, short generation time, genome wide geographic distribution make it ideal natural variation. Genome-wide association studies (GWAS) have proven a useful technique identifying genetic loci responsible variation in A. thaliana. Previously genotyped accessions (natural inbred lines) can be grown replicate under different conditions...
Abstract Human land use has caused substantial declines in global species richness. Evidence from different taxonomic groups and geographic regions suggests that does not equally impact all organisms within terrestrial ecological communities, functional of may respond differently. In particular, we expect large carnivores to decline more disturbed uses than other animal groups. We present the first synthesis responses across using data a wide set species, including herbivores, omnivores,...
Summary A major strength of Arabidopsis thaliana as a model lies in the availability large number naturally occurring inbred lines. Recent studies A. population structure, using thousands accessions from stock center and natural collections, have revealed robust pattern isolation by distance at several spatial scales, such that genetically identical individuals are generally found close to each other. However, some individual deviate this pattern. While these may be products rare...
<ns4:p>It is well understood that genetic differences among hosts contribute to variation in pathogen susceptibility and the ability associate with symbionts. However, it remains unclear just how influential host genes are shaping overall microbiome. Studies of both animal plant microbial communities indicate impact species richness abundances individual taxa. Analyses beta diversity (that is, similarity), on other hand, often conclude play a minor role communities. In this review, we...
Plants are constantly challenged by pathogens, which can cause substantial yield losses. The aggressiveness of and damage pathogens depends on the host-associated microbiome, might be shaped plant genetics to improve resistance. How different crop genotypes modulate their microbiota when a complex is largely unknown. Here, we investigate if how pea ( Pisum sativum L.) shape root upon challenge soil-borne this relates genotype's Building phenotyping efforts 252 grown in naturally infested...
Abstract The capacity to tolerate freezing temperatures limits the geographical distribution of many plants, including several species agricultural importance. However, genes involved in tolerance remain largely unknown. Here, we describe variation constitutive that occurs among worldwide accessions Arabidopsis thaliana . We found although plants from high latitudes tend be more tolerant than low latitudes, environmental factors shape cold adaptation differ across range. Consistent with...
Environmental heterogeneity is a major driver of plant-microbiome assembly, but the specific climate and soil conditions that are involved remain poorly understood. To better understand plant microbiome formation, we examined bacteria fungi colonize wild strawberry (Fragaria vesca) plants in North American European populations. Using transects as replicates, found strong overlap among environmental best predict overall similarity richness microbiome, including nutrients replicate across...
We have created a suite of Java-based software to better provide taxonomic assignments DNA sequences. anticipate that the program will be useful for protistologists, virologists, mycologists and other microbial ecologists. The relies on NCBI utilities including BLAST Taxonomy database is easily manipulated at command-line specify candidate's query-coverage or percent identity requirements; options include ability set minimal consensus requirements (%) each eight major ranks (Domain, Kingdom,...
There is currently tremendous interest in the possibility of using genome-wide association mapping to identify genes responsible for natural variation, particularly human disease susceptibility. The model plant Arabidopsis thaliana many ways an ideal candidate such studies, because it a highly selfing hermaphrodite. As result, species largely exists as collection naturally occurring inbred lines, or accessions, which can be genotyped once and phenotyped repeatedly. Furthermore, linkage...
With large-scale genomic data becoming the norm in biological studies, storing, integrating, viewing and searching of such have become a major challenge. In this article, we describe development an Arabidopsis thaliana database that hosts geographic information genetic polymorphism for over 6000 accessions genome-wide association study (GWAS) results 107 phenotypes representing largest collection GWAS to date. Taking advantage series latest web 2.0 technologies, as Ajax (Asynchronous...
Root rot is one of the most threatening diseases to pea production. caused by several interacting soil-borne pathogens, which makes it challenging manage. Breeding for resistance a promising approach sustainable While quantitative trait loci (QTL) against individual pathogens have been identified, genetic basis underlying pathogen complex poorly understood. Using previously described diverse panel 254 genotypes and 18k single nucleotide polymorphism (SNP) markers, we identified novel QTL...