A5015117388- Salmonella and Campylobacter epidemiology
- Antibiotic Resistance in Bacteria
- SARS-CoV-2 and COVID-19 Research
- Escherichia coli research studies
- Vaccine Coverage and Hesitancy
- Microbial Metabolism and Applications
- Enterobacteriaceae and Cronobacter Research
- Viral gastroenteritis research and epidemiology
- Bacteriophages and microbial interactions
- COVID-19 epidemiological studies
- Probiotics and Fermented Foods
- Listeria monocytogenes in Food Safety
- Microbial Natural Products and Biosynthesis
- Bacterial Identification and Susceptibility Testing
- Helicobacter pylori-related gastroenterology studies
- Fungal Biology and Applications
- Vibrio bacteria research studies
- Plant Pathogens and Fungal Diseases
- Veterinary medicine and infectious diseases
- Gut microbiota and health
- Immune responses and vaccinations
- Virology and Viral Diseases
- Clostridium difficile and Clostridium perfringens research
- Pharmaceutical and Antibiotic Environmental Impacts
- Yersinia bacterium, plague, ectoparasites research
Saint Petersburg Pasteur Institute
2014-2025
Ural Branch of the Russian Academy of Sciences
2024
The Russian Presidential Academy of National Economy and Public Administration
2015
Specific prevention of measles, mumps, and rubella (MMR) is the main prerequisite for a radical reduction in incidence these infections Kyrgyz Republic (KR). An increase number seronegative individuals observed recent years has led to an measles incidence. This directly related decrease collective immunity, which provides protection population only conditions high density immunized their uniform distribution population. The way estimate by conducting serological surveys immunity. Aim study:...
Extended-spectrum beta-lactamases (ESBL) and AmpC producing-Escherichia coli have spread worldwide, but data about ESBL-producing-E. in the Northern Eastern regions of Europe is scant. The aim this study has been to describe phenotypical molecular epidemiology different ESBL/AmpC/Carbapenemases genes E. strains isolated from Baltic States (Estonia, Latvia, Lithuania), Norway St. Petersburg (Russia), determine predominant multilocus sequence type single nucleotide polymorphisms diversity...
Abstract The multidrug-resistant (MDR) Salmonella enterica serotype Newport strain that produces CMY-2 β-lactamase (Newport MDR-AmpC) was the source of sporadic cases and outbreaks in humans France during 2000–2005. Because this not detected food animals, it most likely introduced into through imported products.
We studied the prevalence of resistance to extended-spectrum cephalosporins (ESC) among 1,078 Salmonella enterica isolates collected from adults admitted Botkin Hospital, St. Petersburg, Russia, for gastroenteritis between 2002 and 2005. Only two ESC-resistant were detected, giving a low percentage strains resistant ESC (0.2%). One multidrug-resistant (MDR) isolate Virchow serotype produced CTXM-3 β-lactamase (ESBL). The blaCTX-M-3 gene was located downstream an ISEcp1 element, on 80-kb...
The spread of carbapenemase-producing Enterobacteriaceae is a global problem; however, no exact data on the epidemiology carbapenemase in Baltic countries and St. Petersburg area available. We aimed to evaluate Escherichia coli Klebsiella pneumoniae States Petersburg, Russia, compare different methods for detection. From January May 2012, all K. (n = 1983) E. 7774) clinical isolates from 20 institutions Estonia, Latvia, Lithuania, Russia were screened carbapenem susceptibility. IMP, VIM,...
Objective was to investigate the SARS-CoV-2 collective immunity status of population Belarus within context COVID-19 pandemic. Materials and methods. The work carried out according methodology for assessing immunity, developed by Rospotrebnadzor Russia Ministry Health with participation St. Petersburg Pasteur Institute, taking into account WHO recommendations. Bioethics Committee local ethics committee Institute approved study. Selection participants using a questionnaire method online...
Abstract. We studied the prevalence of K. pneumoniae and E. coli resistance to extended spectrum cephalosporins carbapenems, isolated from patients eight hospitals in St-Petersburg January May, 2012. Prevalence cephalosporin resistant isolates varied different hospitals: – 7,8 50%, 25,4 88,4%. Isolates produced beta-lactamases СТХ-М, mainly СТХ-М-1, also СТХ-М-2 СТХ-М-9. Twenty two carbapenem-resistant strains (also other antimicrobials) were three hospitals. MALDI-TOF MS showed that...
This study has evaluated the correlation between different carbapenemases detection methods on carbapenem non-susceptible Klebsiella pneumoniae strains from Northern and Eastern Europe; 31 institutions in 9 countries participated research project, namely Finland, Estonia, Latvia, Lithuania, Russia, St. Petersburg, Poland, Belarus, Ukraine, Georgia. During program, a total of 5,001 clinical K. isolates were screened for any non-susceptibility by disk diffusion method, Vitek 2 or Phoenix...
Abstract. Strains of Klebsiella pneumonia isolated from faces were studied to detect virulence factors “classical” enteric pathogens causing acute diarrhea (Shigella, Salmonella, diarreagenic Escherichia coli). We haven’t in the genes encode different factors: abilities adherence (sfa, afa, aaf/1, eae), invasion (ipaH, ial), production heat-lable toxins (elt, LT II), heat-stable (st1, st2) and Shiga (stx1, stx2). spp. is well-known pathogen opportunistic infections urinary tract, blood,...
The gut microbiota of healthy people, living in different regions, may vary considerably. article presents the results comparative qualitative and quantitative study intestine aerobic anaerobic residents Republic Guinea (46) Russia (60). content microorganisms (Enterobacteriaceae, Enterococcus spp., Lactobacillus Bifidobacterium Staphylococcus Candida non-fermentative gram-negative bacteria others) 1.0 gram faeces was determined by bacteriological methods. Generic species identification...
Despite all efforts of the world community, COVID-19 pandemic remains one main epidemiological challenges our time. Even with its widespread distribution, infection may have certain local features due to social, geographic, and climatic factors. Objective: study collective immunity SARS-CoV-2 in population Republic Tajikistan. A cross-sectional, randomized herd was carried out according a program developed by Rospotrebnadzor St. Petersburg Pasteur Institute, taking into account WHO...
Background. The COVID-19 pandemic has become a substantial global health crisis, unparalleled in world history. Infection dynamics can have specific characteristics different countries due to social, economic, climatic, or geographic factors. Aim: study features of SARS-CoV-2 collective immunity among the Armenian population. Materials and methods. A cross-sectional, randomized was carried out according program developed by Rospotrebnadzor St. Petersburg Pasteur Institute, taking into...
The Сomamonas genus, described in 1985, included one species — terrigena. At present, the genus includes 21 species. ability of Comamonas to survive environmental objects (samples water, soil and plants), including hospital environment medical equipment, allows them be considered as opportunistic microorganisms. purpose research was study biological properties antimicrobial susceptibility kerstersii strains isolated from fecal samples healthy people living Saint Petersburg (Russian...
The article presents the results of antimicrobial resistance monitoring Salmonella isolated from children and adults with diarrhea in St. Petersburg 2014-2018. In 746 isolates 42 serovars more than 90,0% belonged to three: S. enteritidis (79,6%), typhimurium (6,8%) infantis (3,8%). susceptibility testing (according EUCAST) 7 classes antimicrobials revealed 78,6% Salmonella. Low-level quinolone (MIC ciprofloxacin 0,12-0,5 mg/l) was detected 63,3% (S. -71,0%, - 15,7%, 89,3%) due five kinds...
Here we present current global epidemiological and microbiological trends for typhoid fever, as well describe antimicrobial susceptibility resistance mechanisms of S. Typhi. The data on examining 299 Typhi isolates collected in 2005—2018 the Russian Federation were analyzed from Reference Center. It was found that population consisted with different phenotypes genetic heterogeneity. Moreover, detected low 10.4% strains, whereas 89.6% showed fluoroquinolone (including 7.3% high-level...
Recent studies have shown that bacterial resistance existed long before antimicrobials were used in medicine, and not only pathogens are resistant to antibiotics. 511 strains of E. coli isolated from the intestinal microbiota children aged 1 month 17 years living St. Petersburg studied: susceptibility 15 antibiotics was determined by disk diffusion method, as well 6 commercial bacteriophages produced «Microgen» (Russia). The b-lactamase genes molecular families TEM, SHV, OXA, CTX-M detected...
<title>Abstract</title> Clarithromycin (CLR) is a key drug to treat <italic>Helicobacter pylori</italic> infection, however the data on CLR resistance patterns in Russia are missing. Here, we applied next-generation sequencing (NGS)-based approach <italic>H. clinical isolates from comprehensively investigate sequence variations, identify putative markers of and correlate them with phenotypic susceptibility testing (DST). The 44 (2014–2022) was determined by disc diffusion method. All were...
Clarithromycin (CLR) is currently a key antibiotic for Helicobacter pylori infection treatment, however, the data on CLR resistance patterns in Russia are missing. Here, we applied WGS-based approach to H. clinical isolates from comprehensively investigate sequence variation, identify putative markers of and correlate them with phenotypic susceptibility testing. The 44 (2014-2022) was determined by disc diffusion method: 23 were CLR-resistant 21-CLR-susceptible. All subjected WGS submitted...
Objective. To identify point mutations in 23S rRNA gene associated with phenotypic drug resistance to clarithromycin (CLR) clinical isolates of H. pylori. Materials and Methods. A total 50 pylori (2014–2022) from adult patients chronic gastritis (n = 32), duodenal ulcer 11) gastric cancer 1) were included this study. Of isolates, 30 obtained newly diagnosed patients, 20 – previously treated after eradication failure. All cultured on supplemented Columbia agar incubated under microaerophilic...
The article presents the stages of development Department Humanitarian Interdisciplinary Research, Komi Science Centre Ural Branch Russian Academy Sciences: establishment Scientific Archive (1953), its reorganization into “Scientific and Encyclopedia” (2005), transformation Research with group Archive” (2015). In past decades, traditions storing, accounting, introducing documents archive scientific circulation were formed strengthened; experience conducting source studies, creating a photo...