Jonathan Berg
- Circadian rhythm and melatonin
- Effects of Radiation Exposure
- Light effects on plants
- Telomeres, Telomerase, and Senescence
- Genetics, Aging, and Longevity in Model Organisms
- Spaceflight effects on biology
- Immunotherapy and Immune Responses
- Hematopoietic Stem Cell Transplantation
University of California, Davis
2022-2024
RELX Group (United States)
2019-2023
Potential systemic factors contributing to aging-associated breast cancer (BC) remain elusive. Here, we reveal that the polyploid giant cells (PGCs) contain more than two sets of genomes prevailing in aging and cancerous tissues constitute 5-10% healthy female bone marrow mesenchymal stromal (fBMSCs). The PGCs can repair DNA damage stimulate neighboring for clonal expansion. However, dying advanced-senescent fBMSCs form "spikings" which are then separated into membraned mtDNA-containing...
Circadian rhythm (CR) and low-dose radiation (LDR) evident on Earth’s surface may have coordinated in the evolution of original life forms. Disturbed CR or overexposure to are well documented cause aging diseases, both tumor normal tissues show CR-related radiosensitivity. However, it is unclear how proteins participate LDR-mediated adaptive radioprotection. Herein, we demonstrate that mice carrying a deficient Period2 gene (C57BL-Per2def) core regulator were highly radiosensitive with...