A5101959939- Pancreatic and Hepatic Oncology Research
- Diabetes Management and Research
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic function and diabetes
- Neuroendocrine Tumor Research Advances
- Ovarian function and disorders
- Diabetes and associated disorders
- Metabolism, Diabetes, and Cancer
- Pediatric Hepatobiliary Diseases and Treatments
- Pediatric Urology and Nephrology Studies
- Diabetes Management and Education
- S100 Proteins and Annexins
- Birth, Development, and Health
- Diet, Metabolism, and Disease
- Hormonal and reproductive studies
- Appendicitis Diagnosis and Management
- Hypothalamic control of reproductive hormones
- Sexual Differentiation and Disorders
- Lysosomal Storage Disorders Research
- Carbohydrate Chemistry and Synthesis
- Congenital Anomalies and Fetal Surgery
- Cancer-related molecular mechanisms research
- Nutrition and Health in Aging
- Testicular diseases and treatments
- Neurogenetic and Muscular Disorders Research
Xinjiang Medical University
2025
Second Affiliated Hospital of Nanjing Medical University
2024
National Health and Family Planning Commission
2023
Sichuan University
2021-2023
West China Hospital of Sichuan University
2023
Pudong New Area People's Hospital
2021
Children's Hospital of Chongqing Medical University
2018-2021
Chongqing Medical University
2018-2021
Sun Yat-sen Memorial Hospital
2020
Sun Yat-sen University
2020
Osteosarcoma is the most common primary bone tumor in children and adolescents. Its pathogenesis complex poses difficulties treatment. Autophagy a cell biological process that plays crucial role mechanistic study treatment of osteosarcoma. The objective this to evaluate past research progress from 2007 2023 visualize key directions through bibliometric methods. Relevant publications published start end were searched screened Web Science Core Collection. They analyzed visualized using...
Many studies have examined the relationships between body composition and bone mineral density (BMD), but little attention has been given to how these vary by age sex. The aim of this study was investigate distributions lean mass (LM), fat (FM), BMD correlation in Chinese men women different ages.In total, compositions 1,475 1,534 aged 20 96 years were analyzed. Using dual-energy x-ray absorptiometry, we measured spine, femur, total LM, FM, percentage (Fat %). population divided into groups...
In 1970, a gastric adenocarcinoma patient with increased alpha fetoprotein (AFP) in his serum and liver metastatic tumor was reported by Bourreilile et al.1 At that time, it realized could produce AFP. 1985, Ishikura al2 hepatocellular carcinoma (HCC)-like differentiation primary first proposed the conception of “hepatoid carcinoma”. Subsequent documentation this unique histopathologic feature has been made other extrahepatic sites including esophagus, papilla Vater, colon, lung,...
Todani classification is extensively used to guide the surgical strategy of choledochal cysts, but no systematic investigations on distal management intrapancreatic cysts have been conducted. This study reports and in adults based relation between cyst pancreatic duct. Patients with who underwent operation, including management, our department from January 2009 December 2014 were retrospectively reviewed. presenting symptoms, coexisting diseases, treatment, perioperative complications,...
Background. 3β-HSD deficiency is a rare type of congenital adrenal hyperplasia (CAH), which caused by HSD3B2 gene mutations.Objectives.In order to improve the understanding and diagnosis disease, we analyzed summarized clinical characteristics, genetic variants treatment for 3 children with in this study. Materials methods.A summary data, hormone levels (17-hydroxyprogesterone, adrenocorticotropic hormone, cortisol, testosterone, dehydroepiandrosterone, androstenedione, renin, aldosterone),...
The current study aims to evaluate the expression pattern changes of miR-199-3p in diabetic nephropathy (DN) patients and explore whether it could be used as a potential biomarker.Real time PCR analysis was performed examine level normoalbuminuria group (diabetes mellitus [DM]), microalbuminuria (DNE), macroalbuminuria (DNC), healthy controls. ROC carried out determine urine biomarker. Dual luciferase reporter assay identify target gene miR-199-3p.Here we showed novel data that significantly...
Background Laparoscopic pyeloplasty is a minimally invasive approach for the therapy of infant ureteropelvic junction obstruction (UPJO), reliant on CO 2 pneumoperitoneum insufflation. While impact insufflation adult and older pediatric populations has been studied, its effects infants remain less explored. Methods This prospective randomized controlled trial included with UPJO undergoing laparoscopic pyeloplasty. Patients were allocated to low pressure (LPP, 5 mmHg) or high (HPP, 8 groups....
Background: Lipohypertrophy (LH) is harmful and requires early diagnosis. While LH typically detected by inspection palpation (physical examination), the reliability potentially low. We evaluated prevalence contributing risk factors for missed compared to ultrasound scanning (USS). Methods: This was a cross-sectional study included 260 patients who had injected insulin continuously at least 1 year. Physical examination USS were used meanwhile. Associations between diagnosis clinical,...
To investigate the effects of Niaoduqing granule on urine metabolic profile in chronic renal failure (CRF) rats.Thirty six male SD rats were divided into normal control group, model and group with 12 each group. The CRF was induced by gavage 250 mg·kg-1·d-1 adenine for 21 d. UPLC-Q-TOF-MS/MS technique used combination principal component analysis (PCA) partial least squares discriminant (PLS-DA) to analyze profiles three groups. endogenous substances variable importance projection (VIP)>1...
To survey the quality of life in children and adolescents with type 1 diabetes.Ninety-eight diabetes who participated Diabetes Summer Camp held Chongqing, Wuhan Cheng during 2012 April December were recruited study. The American juvenile patients scale Quality Life for Youths was used to assess SPSS19.0 statistical analysis.The had satisfactory reliability validity a Cronbach's Alpha score 0.942 0.679. All three dimension scales: scales impact, worries satisfaction significantly correlated...
Objective To improve the recognition for infantile spinal muscular atrophy (SMA-I) and level of early diagnosis, intervention treatment SMA-I. Methods The clinical data 39 patients with SMA-I were analyzed retrospectively, including manifestations, neural electrophysiological characteristics, genotype, prognosis SMA-I. Results Of cases , 37 cases(94.9%) had onset in 6 months after birth.The paralyses limbs symmetrical flaccid.The lower was more severe than upper proximal distal,...
Objective To investigate the clinical features and treatment of solid pseudopapillary neoplasm (SPN) pancreas. Methods The retrospective cross-sectional study was conducted. The clinicopathological data 69 patients with SPN pancreas who were admitted to Qilu Hospital Shandong University from January 2012 July 2017 collected. Serum tumor markers detection, enhanced computed tomography (CT) magnetic resonance imaging (MRI) abdomen carried out preoperatively for all patients, a part...
摘要 本研究旨在探讨戈谢病Ⅱ型的临床特点及诊断思路. 先证者, 女, 1岁1个月时因"营养不良, 智力运动倒退" 来院.患儿生后"嗓子呼噜, 痰多", 疑诊断"喉喘鸣"; 6个月后体重增长缓慢, 被诊断"营养不良"; 9个月后智力运动 倒退, 接受康复训练无效; 1岁1个月时发现脾肿大、贫血、血小板减少, 并出现惊厥发作, 来院进行病因分析.外 周血白细胞葡萄糖脑苷脂酶(GBA)活性显著减低(0.4 nmol g -1 min , 正常对照2.63~25.6 ), 血浆壳 三糖酶活性显著升高(54000.5 L 正常对照0~25145 ).靶向捕获二代测序法及Sanger 测序法验证对患儿GBA基因进行分析发现已知致病的复合杂合突变, c.703T>C(p.S235P)和c.1205A>G(p.Y402C),
Background: Adolescent with type 1 diabetes (T1D) experience increased distress, which is linked to poor self-management and glycemic control. Resilience might be able decrease distress facilitate disease management. Objective: To determine whether resilience buffers the deleterious consequences of on control self-management. Methods: A convenience sample 203 eligible adolescents (mean age 14.60 years) was recruited from a national endocrine center. Data were collected social clinical...