A5091898921- Plant Pathogens and Fungal Diseases
- Plant Virus Research Studies
- Plant Pathogens and Resistance
- CRISPR and Genetic Engineering
- Yeasts and Rust Fungi Studies
- Insect symbiosis and bacterial influences
- Mycorrhizal Fungi and Plant Interactions
- Plant and Fungal Interactions Research
- Obstructive Sleep Apnea Research
- Plant and animal studies
- Cardiovascular Syncope and Autonomic Disorders
- Genetic diversity and population structure
- Gastroesophageal reflux and treatments
- Plant-Microbe Interactions and Immunity
- Tracheal and airway disorders
- Dysphagia Assessment and Management
- Fungal Biology and Applications
- Genomics and Phylogenetic Studies
- Plant Disease Resistance and Genetics
- Esophageal and GI Pathology
University of British Columbia
2020-2025
Canadian Food Inspection Agency
2021
Oregon State University
2021
University of Victoria
2016
Antwerp University Hospital
2016
University of Calgary
2012
ABSTRACT CRISPR-Cas9 gene editing has become an important tool for the study of plant pathogens, allowing researchers to functionally characterize specific genes involved in phytopathogenicity, virulence, and fungicide resistance. Protocols have already been developed Phytophthoras, group oomycete pathogens; however, these efforts exclusively focused on agricultural pathosystems, with research lacking forest pathosystems. We sought develop two pathogenic Phytophthora cactorum P. ramorum ,...
Phytophthora is a long-established, well known and globally important genus of plant pathogens. Phylogenetic evidence has shown that the biologically distinct, obligate biotrophic downy mildews evolved from at least twice. Since, cladistically, this renders ‘paraphyletic’, it been proposed evolutionary clades be split into multiple genera (Runge et al. 2011; Crous 2021; Thines 2023; 2024). In letter, we review arguments for retention generic name with broad circumscription made by Brasier...
Invasive plant pathogenic fungi have a global impact, with devastating economic and environmental effects on crops forests. Biosurveillance, critical component of threat mitigation, requires risk prediction based fungal lifestyles traits. Recent studies revealed distinct genomic patterns associated specific groups fungi. We sought to establish whether these phytopathogenic hold across diverse taxonomic ecological from the Ascomycota Basidiomycota, furthermore, if those can be used in...
The treatment of head and neck cancer is associated with significant dysphagia morbidity. Prescribing a safe oral diet in this population challenging.Data from 116 consecutive patients having 189 fiber-optic endoscopic evaluation swallowing (FEES) examinations over 3-year period were analyzed. All had been treated for subsequently assessed by FEES. primary outcome was the incidence swallowing-related adverse events resulting FEES-based dietary recommendations.There 10 episodes aspiration...
Plasmid-mediated DNA transformation is a foundational molecular technique and the basis for most CRISPR-Cas9 gene editing systems. While plasmid transformations are well established many agricultural Phytophthora pathogens, development of this in forest Phytophthoras lacking. Given our long-term research objective to develop pathogenic species, we sought establish functionality polyethylene glycol (PEG)-mediated five species: P . cactorum , cinnamomi cryptogea ramorum syringae We used...
Abstract Invasive exotic pathogens pose a threat to trees and forest ecosystems worldwide, hampering the provision of essential ecosystem services such as carbon sequestration water purification. Hybridization is major evolutionary force that can drive emergence pathogens. Phytophthora ramorum , an emergent pathogen causes sudden oak larch death, spreads reproductively isolated divergent clonal lineages. We use genomic biosurveillance approach by sequencing genomes P. from survey inspection...
Editorial-BellIt is quite possible that we are very likely going to see a greater dependence on remote data collection of this type as the sophistication and reliability units improves.It certainly behooves us find ways adapt our treatment modalities successfully interface with these newer modes.The future success dental professionals in arena depends ability be nimble new technologies they emerge.
The ability to develop robust machine-learning (ML) models is considered imperative the adoption of ML techniques in biology and medicine fields. This challenge particularly acute when data available for training not independent identically distributed (iid), which case trained are vulnerable out-of-distribution generalization problems. Of particular interest problems where correspond observations made on phylogenetically related samples (e.g. antibiotic resistance data).We introduce...
Abstract Plasmid-mediated DNA transformation is a foundational molecular technique and the basis for most CRISPR-Cas9 gene editing systems. While plasmid transformations are well established many agricultural Phytophthora pathogens, development of this in forest Phytophthoras lacking. Given our long-term research objective to develop pathogenic species, we sought establish functionality polyethylene glycol (PEG)-mediated five species: P. cactorum , cinnamomi cryptogea ramorum syringae . We...
Abstract Invasive plant pathogenic fungi have a global impact, with devastating economic and environmental effects on crops forests. Biosurveillance, critical component of threat mitigation, requires risk prediction based fungal lifestyles traits. Using machine learning approach that separates phylogenetic genomic feature signals, we analyzed 387 genomes to test the hypothesis there are predictive signatures associated phytopathogenic Our results lend strong support this hypothesis, our...
Abstract Invasive exotic pathogens pose a threat to trees and forest ecosystems worldwide 1 , hampering the provision of essential ecosystem services such as carbon sequestration water purification 2 . Hybridization is major evolutionary force that can drive emergence 3 Phytophthora ramorum an emergent pathogen causes sudden oak larch death, spreads reproductively isolated divergent clonal lineages. Sexual recombination has never been reported in this under natural conditions laboratory...