A5002493998- Lung Cancer Treatments and Mutations
- Lymphoma Diagnosis and Treatment
- Chronic Lymphocytic Leukemia Research
- Acute Myeloid Leukemia Research
- Hematopoietic Stem Cell Transplantation
- Lung Cancer Diagnosis and Treatment
- Lung Cancer Research Studies
- Venous Thromboembolism Diagnosis and Management
- Acute Lymphoblastic Leukemia research
- Sarcoma Diagnosis and Treatment
- Erythrocyte Function and Pathophysiology
- Bone Tumor Diagnosis and Treatments
- Immune Cell Function and Interaction
- Cardiac tumors and thrombi
- Tracheal and airway disorders
- Blood disorders and treatments
- Neutropenia and Cancer Infections
- Colorectal Cancer Treatments and Studies
- Hematological disorders and diagnostics
- Viral-associated cancers and disorders
- Atrial Fibrillation Management and Outcomes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Gastric Cancer Management and Outcomes
- Pneumocystis jirovecii pneumonia detection and treatment
- Oral and Maxillofacial Pathology
Shimane University
2016-2025
Shimane Prefectural Central Hospital
2023-2024
Kobe Gakuin University
2024
Hiroshima Prefectural Hospital
2023
Hiroshima University Hospital
2023
Kōchi University
2023
Saitama Medical University
2023
Japanese Red Cross Hiroshima College of Nursing
2023
ORCID
2020
Nagoya Medical Center
2009-2019
ABSTRACT Background Cancer‐associated thromboembolism has been thoroughly investigated in previous studies, and direct oral anticoagulants (DOACs) were established for the treatment prevention of venous (VTE). However, risks cancer‐associated arterial (ATE) efficacy DOACs remain unclear. Objectives To evaluate risk factors clinical activity edoxaban (EDO) ATE patients with advanced lung cancer. Methods From prospective Rising‐VTE/NEJ037 study which VTE newly diagnosed cancer, we incidence...
Background The identification and purification of keratinocyte stem cells (KSCs) that are capable self‐renewal maintenance differentiating cell populations could contribute both to our understanding the biology these cells, significant clinical applications, such as culturing keratinocytes for transplantation severe burn wounds. Here, we report detection CD90+ in cultured normal human epidermal adult skin. Objectives To investigate biological function CD90− keratinocytes. Methods were...
In musculoskeletal sarcomas, brain metastases are rare, but severely affect quality of life.All patients with sarcomas who were treated at our institutions from 1975 to 1997 reviewed for examples metastasis.Of 480 sarcoma patients, 179 had distant metastases, including 20 (4.2%). Alveolar soft part (3/4), extraskeletal Ewing's (2/8), rhabdomyosarcoma (2/13) and bone (2/18) tended metastasize the brain. All or local relapses 16 pulmonary metastases. Three underwent surgical treatment two them...
To distinguish between benign and malignant peripheral nerve sheath tumors around the pelvis.A retrospective study of 30 patients with located pelvis was performed. Clinical, imaging histological features 19 11 were reviewed retrospectively.Nearly all exhibited pain at presentation in cases involving both tumors. Although tumor size, duration symptoms presence sensory disturbance possessed little value differential diagnosis, severe motor weakness observed exclusively presenting On CT or...
We examined osteochondral autografts, obtained at a mean of 19.5 months (3 to 48) following extracorporeal irradiation and re-implantation replace bone defects after removal tumours. The specimens were from six patients (mean age 13.3 years (10 18)) consisted articular cartilage (five), subchondral external callus (one) tendon (one). tumour cells in the grafts eradicated by single radiation dose 60 Gy. In three specimens, viable chondrocytes detected. survival was confirmed with S-100...
Venous thromboembolism (VTE) is a well-known type of cancer-associated thrombosis and common complication malignancy. However, the incidence VTE associated with lung cancer effectiveness direct oral anticoagulants remain unclear. This study aimed to identify at time diagnosis or during treatment, efficacy safety edoxaban, risk factors.The Rising-VTE/NEJ037 was multicenter prospective observational study. Altogether, 1021 patients who were unsuitable for radical resection radiation enrolled...
3'-Azido-2',3'-dideoxythymidine is known to cause severe anemia and neutropenia. Although these are rare for 2',3'-dideoxycytidine, it frequently impairs thrombocytogenesis. These differential myelossuppressive features correlated well with the in vitro toxicities of drugs a megakaryoblastic cell line colony formation erythroid granulocytic cells.
The central nervous system is a common site of relapse in patients receiving crizotinib, which presumed to be associated with the low concentration crizotinib cerebrospinal fluid (CSF). Our patient received surgical treatment for anaplastic lymphoma kinase-positive stage IIA lung adenocarcinoma. His cancer recurred brain metastases and carcinomatous meningitis. We started whole-brain radiation therapy (WBRT) subsequently administered crizotinib. on day 15 plasma was 158 ng/mL, that spinal...
Management of cancer-associated venous thromboembolism (VTE) is essential in cancer treatment selection and prognosis. However, currently, no method exists for assessing VTE risk associated with advanced lung cancer. Therefore, we assessed risk, including driver gene mutation, performed a Khorana score validation.The Rising-VTE/NEJ037 study was multicenter prospective observational that included patients In the study, calculated enrolled available data on all components. The modified based...