A5078556999- Infection Control and Ventilation
- COVID-19 and healthcare impacts
- Anesthesia and Sedative Agents
- Airway Management and Intubation Techniques
- Neutropenia and Cancer Infections
- SARS-CoV-2 and COVID-19 Research
- SARS-CoV-2 detection and testing
- Respiratory viral infections research
- Anesthesia and Pain Management
- Obstructive Sleep Apnea Research
- Tracheal and airway disorders
- Hematological disorders and diagnostics
- Chronic Myeloid Leukemia Treatments
- Pediatric Pain Management Techniques
- Ocular Surface and Contact Lens
- COVID-19 and Mental Health
- Glaucoma and retinal disorders
- COVID-19 epidemiological studies
- Pain Management and Treatment
- COVID-19 Impact on Reproduction
- Burkholderia infections and melioidosis
- Management of metastatic bone disease
- Polyomavirus and related diseases
- Vascular anomalies and interventions
- Drug Transport and Resistance Mechanisms
University of Toronto
2011-2025
Sunnybrook Health Science Centre
2011-2025
University of California, San Francisco
2025
Health Sciences Centre
2012-2025
Abbotsford Veterinary Clinic
2022
DSO National Laboratories
2004-2021
Surrey Memorial Hospital
2021
Royal Columbian Hospital
2021
Western University
2021
University of British Columbia
2021
This study documents results of SARS-CoV-2 polymerase chain reaction (PCR) testing environmental surfaces and personal protective equipment surrounding 3 COVID-19 patients in isolation rooms a Singapore hospital.
Abstract Understanding the particle size distribution in air and patterns of environmental contamination SARS-CoV-2 is essential for infection prevention policies. Here we screen surface samples from hospital rooms COVID-19 patients RNA. Environmental sampling conducted three airborne isolation (AIIRs) ICU 27 AIIRs general ward. 245 are collected. 56.7% have at least one contaminated. High touch shown ten (66.7%) out 15 first week illness, (20%) beyond illness ( p = 0.01, χ 2 test). Air...
Abstract Cytomegalovirus (CMV) infection and disease are important causes of morbidity mortality in transplant recipients. For the purpose developing consistent reporting CMV outcomes clinical trials, definitions were developed most recently published 2017. Since then, there have been major developments, including registration new antiviral agents. Therefore, Transplant Associated Virus Infections Forum, which consists scientists, clinicians, regulators, industry representatives, has...
Abstract Understanding the particle size distribution in air and patterns of environmental contamination SARS-CoV-2 is essential for infection prevention policies. We aimed to detect surface study associated patient-level factors. 245 samples were collected from 30 airborne isolation rooms COVID-19 patients, sampling was conducted 3 rooms. Air detected PCR-positive particles sizes >4 µm 1-4 two rooms, which warrants further transmission potential SARS-CoV-2. 56.7% had at least one...
An abstract is not available for this content. As you have access to content, full HTML content provided on page. A PDF of also in through the 'Save PDF' action button.
Abstract Background: Understanding the extent of aerosol-based transmission severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is important for tailoring interventions control disease 2019 (COVID-19) pandemic. Multiple studies have reported detection SARS-CoV-2 nucleic acid in air samples, but only one study has successfully recovered viable virus, although it limited by its small sample size. Objective: We aimed to determine shedding aerosols from COVID-19 patients. Methods: In...
Abstract Objective Explore the experiences of stakeholders within hearing care pathways using a human‐centered design process to patient navigator (PN) improve health equity for deaf or hard‐of‐hearing children. Study Design A qualitative, prospective, observational study utilizing Empathize, Define, and Ideate phases Human‐Centered Design. Setting Academic tertiary children's hospital with interviews over Zoom. Methods We interviewed 12 providers, diverse in role education across United...
Objective Tracheal intubation (TI) consistently induces tachycardia and elevated blood pressure which may be deleterious to patients, particularly those with existing cardiac conditions. Use of dexmedetomidine or esmolol has been described attenuate this sympathetic response. This study aimed determine the effectiveness vs in attenuating hemodynamic response during TI. Methods A systematic review meta-analysis were performed using PRISMA guidelines. literature search electronic databases...
To identify the diurnal variations of tear osmolarity (TO) and its relationship with central corneal thickness (CCT) deswelling over a 14-hour period.TO CCT were measured using TearLab Osmometer Bioptigen spectral domain optical coherence tomography, respectively, on 38 healthy neophytes (mean age, 21.5 ± 2.2 years). TO at bedtime (baseline), upon awakening, 20 minutes, 40 1 hour, 2 hours, 4 8 hours after awakening. Deswelling rate was estimated expressed as percent recovery per hour (PRPH)....
Abstract Background: The risk of environmental contamination by severe acute respiratory coronavirus virus 2 (SARS-CoV-2) in the intensive care unit (ICU) is unclear. We evaluated extent ICU and correlated this with patient disease factors, including impact different ventilatory modalities. Methods: In observational study, surface samples collected from rooms common areas were tested for SARS-CoV-2 polymerase chain reaction (PCR). Select area cell culture. Clinical data to presence...
Background Until recently, viral infections in patients with hematological malignancies were concerns primarily allogeneic hematopoietic stem cell transplant (HSCT) recipients. During the last years, changed treatment regimens for non-transplanted have had potential to increase incidence of this group. In study, we prospectively investigated prevalence a broad range respiratory viruses nasopharyngeal aspirate (NPA) as well that commonly reactivate after HSCT. Methodology/Principal Findings...
ABSTRACT Severe acute respiratory syndrome (SARS) has caused major outbreaks worldwide, resulting in an urgent need to obtain sensitive and accurate diagnosis of this disease. PCR-based detection methods were developed for use on a variety samples, including blood. Eighteen subjects investigated, results indicated that blood samples contain sufficient virus by using quantitative real-time PCR.
Several studies have compared nasal swabs to the more invasive nasopharyngeal aspirate (NPA) for detection of respiratory viruses. Mostly, comparisons been performed on immunocompetent children with upper tract symptoms. The results range from a relatively poor sensitivity an even higher than NPA. We aimed investigate flocked swab (fNS) immunocompromised adults febrile neutropenia. During 16 months, hematological disorder presenting neutropenia were enrolled in study. Paired samples fNS and...
Dermatologic manifestations from therapy with imatinib are well known and frequently include hypopigmentation, less commonly, hyperpigmentation. There have been few reports of oral We present a case palatal melanosis related to for chronic myelogenous leukemia. This is reported add the sparse literature concerning mucosal reactions this medication.
The objective of this study was to determine the prevalence, severity, and duration postoperative pain in children undergoing general anesthesia for dentistry. This prospective cross-sectional included 33 American Society Anesthesiology (ASA) Class I II 4–6 years old requiring multiple dental procedures, including at least 1 extraction, and/or pulpectomy, pulpotomy primary dentition. Exclusion criteria were who developmentally delayed, cognitively impaired, born prematurely, taking...
Background Mannose-binding Lectin protein (MBL) has been suggested to be relevant in the defence against infections immunosuppressed individuals. In a Swedish adult cohort from both underlying disease and iatrogenic treatments for their we investigated role of MBL susceptibility infection. Methods this cross sectional, prospective study, blood samples obtained 96 neutropaenic febrile episodes, representing 82 individuals were analysed single nucleotide polymorphism (SNP) MBL2 gene....
In this study we sought to determine the contribution of microbial translocation febrile episodes with no attributable microbiological cause (Fever Unknown Origin, FUO) in an adult neutropaenic cohort. Endotoxin concentrations were measured chromogenic Limulus Amoebocyte Assay and used as a direct measure bacterial products whilst soluble CD14 (sCD14), ELISA was selected indicator early host response endotoxins. cohort generally elevated but did not differ presentation fever. Further...
The degree of immunosuppression in patients with haematological malignancies treated chemotherapy is routinely measured as number circulating cells (preferable neutrophils) peripheral blood. A parallel decline the T expected, but a possible alteration their functionality has been less well explored. ability to secrete more than one cytokine simultaneously known indicate protective immunity. aim this study was determine whether function altered chemotherapy-induced neutropenia.In...
Post-radiotherapy treatment depends on how the skin within field has reacted during radiotherapy for cancer. Skin reactions can range from mild dull erythema and tightening of to severe moist desquamation, which may result in wounds that be painful sloughy. It is estimated approximately 87% patients will experience a moderate-to-severe reaction. This article discusses an evaluation use polymeric membrane dressing (PolyMem®, Aspen Medical) 23 with following radiotherapy. A purpose-designed...
In March 2020, a state of emergency was declared to facilitate organized responses the coronavirus disease 2019 (COVID-19) pandemic in British Columbia, Canada. Emergency blood management committees (EBMCs) were formed regionally and provincially coordinate transfusion service activities possible national shortages. We describe services COVID-19 regional health authorities Columbia through collaborative survey, contingency planning meeting minutes, policy documents, including early trends...