A5010615115- Mycobacterium research and diagnosis
- SARS-CoV-2 and COVID-19 Research
- Tuberculosis Research and Epidemiology
- Infectious Diseases and Mycology
- Vibrio bacteria research studies
- Urinary Tract Infections Management
- Nosocomial Infections in ICU
- Antifungal resistance and susceptibility
- Bacterial Identification and Susceptibility Testing
- COVID-19 epidemiological studies
- Antibiotic Resistance in Bacteria
- Viral gastroenteritis research and epidemiology
- Nail Diseases and Treatments
- Microscopic Colitis
- Biosensors and Analytical Detection
- Industrial Vision Systems and Defect Detection
- Microbial Community Ecology and Physiology
- Parvovirus B19 Infection Studies
- Kidney Stones and Urolithiasis Treatments
- 3D Printing in Biomedical Research
- Actinomycetales infections and treatment
- Ginseng Biological Effects and Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Sepsis Diagnosis and Treatment
- Clostridium difficile and Clostridium perfringens research
Instituto de Investigación Biomédica de Málaga
2014-2025
Hospital Regional Universitario de Málaga
2012-2025
Hospital Clínico Universitario Virgen de la Victoria
2015
Universidad de Málaga
2014
Hospital Doctor José Molina Orosa
2012
The aim of this study was to compare the results obtained for identification by MALDI-TOF nontuberculous mycobacteria (NTM) isolated in clinical samples with those GenoType Mycobacterium CM/AS (common mycobacteria/additional species). A total 66 isolates from various specimens (mainly respiratory) were tested study. They identified using Bruker strains Lowenstein, following recommended protocol heat inactivation and extraction, simultaneously analyzed through hybridization liquid culture...
The main current diagnostic challenge in Clostridioides difficile infection (CDI) is to detect patients with the poorest prognoses. We have studied association between presence of toxin feces, amplification B gene at low cycles PCR (Ct), and detection binary or ribotype severity, recurrence, poor prognosis. Toxigenic C. has been investigated adult diarrheal regardless clinical request. Glutamate dehydrogenase (GDH), A (TcdA) (TcdB) assessed by immunoassay encoding (tcdB) (cdtA) PCR....
Complicated pyelonephritis (cPN), a common cause of hospital admission, is still poorly-understood entity given the difficulty involved in its correct definition. The aim this study was to analyze main epidemiological, clinical, and microbiological characteristics cPN prognosis large cohort patients with cPN. We conducted prospective, observational including 1325 consecutive older than 14 years diagnosed admitted tertiary university between 1997–2013. After analyzing demographic, clinical...
ABSTRACT We present the first evaluation of a novel molecular assay, Speed-oligo Direct Mycobacterium tuberculosis (SO-DMT) which is based on PCR combined with dipstick for detection mycobacteria and specific identification M. complex (MTC) in respiratory specimens. A blind was carried out two stages: first, under experimental conditions convenience samples comprising 20 negative specimens, 44 smear- culture-positive 11 sputa inoculated various mycobacterium-related organisms; second,...
Background Nucleic acid amplification tests are increasingly used for the rapid diagnosis of tuberculosis. We undertook a comparative study efficiency and diagnostic yield real-time PCR senX3-regX3 based assay versus classical IS6110 target new commercial methods. Methods This single-blind prospective included 145 consecutive samples: 76 from patients with culture-confirmed tuberculosis (86.8% pulmonary 13.2% extrapulmonary tuberculosis: 48.7% smear-positive 51.3% smear-negative) 69 control...
The role of SARS-CoV-2 as the cause chilblains in children remains a matter debate but it is important to elucidate for patient isolation and contact tracing. We sought define etiology, clinical presentation, time course, outcomes presenting emergency department (ED) with cutaneous manifestations shortly after first pandemic peak COVID-19 Spain.A prospective, observational study <15 years age evaluated skin lesions EDs three pediatric hospitals. Children underwent comprehensive work-up...
ABSTRACT The COVID-19 pandemic has shaken the world since beginning of 2020. Spain is among European countries with highest incidence disease during first wave. We established a multidisciplinar consortium to monitor and study evolution epidemic, aim contributing decision making stopping rapid spreading across country. present results for 2170 sequences from wave SARS-Cov-2 epidemic in representing 12% diagnosed cases until 14 th March. This effort allows us document at least 500 initial...
Automated growth-based methods for sterility testing of cell-therapy products should be qualified to demonstrate that they are equivalent to, or better than, the conventional reference method. The aim present study was assess ability BACTEC FX40 system detect low microbial contamination and confirm suitability method in presence seven different human mesenchymal cell-based products, according Ph. Eur. 2.6.27. Additionally, a select best vial fungus performed.Microorganisms representing...