A5041968367- Hepatitis C virus research
- Hepatitis B Virus Studies
- Antifungal resistance and susceptibility
- Bacterial Identification and Susceptibility Testing
- Clinical Laboratory Practices and Quality Control
- Respiratory viral infections research
- Antibiotic Use and Resistance
- Fungal Infections and Studies
- Pneumonia and Respiratory Infections
- Healthcare Systems and Technology
- Liver Disease Diagnosis and Treatment
- HIV, Drug Use, Sexual Risk
- Antimicrobial Resistance in Staphylococcus
- Soil Science and Environmental Management
- Mycobacterium research and diagnosis
- SARS-CoV-2 and COVID-19 Research
- Antibiotic Resistance in Bacteria
- Orthopedic Infections and Treatments
- Medicine and Dermatology Studies History
- COVID-19 Clinical Research Studies
- Streptococcal Infections and Treatments
- Accounting and Financial Management
- Reproductive tract infections research
- Biosensors and Analytical Detection
- Influenza Virus Research Studies
Hospital General Universitario De Valencia
2015-2025
Universitat de València
2013-2024
Fundación Seimc-Gesida
2011
Hospital Clínico Universitario de Valencia
1997-2007
Hospital Universitario Son Dureta
2006
In addition to the increase in fungal infections that has been observed last few decades, it reported severe clinical COVID-19 can risk of invasive infections. The main objective this study was evaluate if there had an candidaemia and pulmonary aspergillosis (IPA) cases since onset SARS-CoV-2 pandemic. Data were retrospectively collected from April 2019 March 2021, patients admitted Consorcio Hospital General Universitario de Valencia (Spain). A total 152 (56 which due Candida auris) 108...
The objective of this study was to analyse whether there is an association between reduced susceptibility biocides in Acinetobacter baumannii and (i) antimicrobial resistance (co-resistance), (ii) prevalent (epidemic) clones, (iii) changes the fitness or (iv) expression genes related efflux pumps porins. Susceptibility antimicrobials determined 49 clonally unrelated isolates A. baumannii. Biological cost, terms mean generation time, by spectrophotometry. Quantitative real-time RT–PCR used...
The multi-resistant yeast Candida auris has become a global public health threat because of its ease to persist and spread in clinical environments, especially intensive care units. One the most severe manifestations invasive candidiasis is candidaemia, whose epidemiology evolved more resistant non-albicansCandida species, such as C. auris. It crucial establish infection control policies order an outbreak due nosocomial pathogens, including implementation screening colonisation studies. We...
Candida auris has become a worrisome multi-drug resistant healthcare-associated pathogen due to its capacity colonise patients and surfaces cause outbreaks of invasive infections in critically ill patients.This study evaluated the outbreak our setting 4-year period, reporting risk factors for developing candidemia previously colonised patients, therapeutic measures outcome colonisation cases among all C. isolates their susceptibility antifungals.Data were retrospectively collected from...
Epidemiological trends show a dramatic increase in the prevalence of fungal infections, and isolation multidrug-resistant species, such as Candida auris. CHROMagarTM (CC; CHROMagar, Paris, France) other chromogenic media, which are widely used clinical laboratory because they allow rapid identification most species. Recently, Plus (CC-Plus; was developed to detect differentiate C. auris addition major albicans, tropicalis, glabrata, or krusei. colonies display differential light blue color...
A shift to Candida non-albicans infections has been noted during the last years, and emergence of multi-resistant auris complicated their management. The aim this study was first compare performance novel chromogenic medium CHROMagar™ Plus (CHROMagar, France) with (Becton Dickinson, Germany) for presumptive identification species; then, evaluate its utility in detection C. surveillance samples. showed a good compared reference Candida. Sensitivity specificity were 100% both media tested...
Pneumococcus is a significant pathogen due to its high morbidity and mortality rates, especially among vulnerable populations. This study investigates the epidemiology of Streptococcus pneumoniae serotypes causing invasive pneumococcal disease in Region Comunidad Valenciana, analyzing data from 1587 isolates collected between 2014 2023. Serotyping antimicrobial sensitivity were assessed, whole genome sequencing was conducted on 104 examine clonal relationships. The found that serotype 8 most...
Hepatitis delta virus (HDV) is the most aggressive form of chronic viral hepatitis, yet substantial knowledge gaps exist regarding its epidemiology and optimal diagnostic workflows. From February 2019 to March 2022, an HBV screening project was conducted across various healthcare settings in Valencia, Spain. This included twenty-six primary care centers, six sexual reproductive health three mental addiction treatment selected hospital departments, outpatient clinics, a penitentiary center. A...
BackgroundCarbapenem-resistant Acinetobacter baumannii (CRAb) is a major source of nosocomial infections in Spain associated with the production OXA-58-like or OXA-24/40-like β-lactamase enzymes. We analysed plasmids carrying blaOXA-24/40-like gene CRAb isolates obtained decade apart.
Abstract Background Rapid and reliable laboratory methods are required for detecting the nosocomial yeast Candida auris . AurisID ® (Olm Diagnostics) is a real‐time PCR assay approved C. in fungal cultures directly from blood samples, involving nucleic acid extraction as prior step. Objectives The purpose of this study to validate kit direct detection surveillance samples without DNA analyse results implementing methodology our daily routine protocol studies. Methods Our method using was...
Abstract Candida auris is a multidrug‐resistant pathogen yeast that produces nosocomial outbreaks, due to its ability in colonizing the skin, mucous membranes and surfaces. Rapid diagnosis essential control spread. The aim of this study was compare Eazyplex® kit (AmplexDiagnostics GmbH) for rapid identification patients colonized with C. , reference method used our institution (culture by MALDI‐TOF). This easy‐to‐perform test allows obtaining fast result, ~30 min. First, we achieved...
ABSTRACT The rapid increase of infections caused by the emerging fungal pathogen Candida auris is global concern, and understanding its expansion a priority. phylogenetic diversity yeast clustered in five major clades, among which clade III particularly relevant, as most strains exhibit resistance to fluconazole, reducing therapeutic alternatives provoking outbreaks that are difficult control. In this study, we have investigated structure analyzing collection 566 genomes. We identified three...
ABSTRACT The rapid increase in infections caused by the emerging fungal pathogen Candida auris is of global concern, and understanding its expansion a priority. phylogenetic diversity yeast clustered five major clades, among which clade III particularly relevant, as most strains exhibit resistance to fluconazole, reducing therapeutic alternatives provoking outbreaks that are difficult control. In this study, we have investigated structure analyzing collection 566 genomes. We identified three...
Previous studies suggested that herpes simplex virus (HSV) PCR testing can be safely deferred in patients with normal cerebrospinal fluid (CSF) white blood cell (WBC) counts and protein levels as long they are older than 2 years of age not immunocompromised, the so-called Reller criteria. In this multicenter study, we retrospectively assessed validity these screening criteria our setting. A total 4,404 CSF specimens submitted for HSV to respective microbiology laboratories at participating...
The SARS-CoV-2 pandemic brought about social changes in 2020 and 2021. aim of this study was to evaluate the epidemiologic profiles main sexually transmitted infections (STIs) bacterial origin (chlamydia, gonorrhea, syphilis) diagnosed during period compare them findings from previous years.