A5072845202- Gestational Diabetes Research and Management
- Pregnancy and preeclampsia studies
- Folate and B Vitamins Research
- Birth, Development, and Health
- Neonatal Health and Biochemistry
- Diabetes Treatment and Management
- Cardiovascular Disease and Adiposity
- Child Nutrition and Feeding Issues
- Heme Oxygenase-1 and Carbon Monoxide
- Neuroendocrine Tumor Research Advances
- Iron Metabolism and Disorders
- Carbon dioxide utilization in catalysis
- Diet, Metabolism, and Disease
- Blood Pressure and Hypertension Studies
- Blood Coagulation and Thrombosis Mechanisms
- Bariatric Surgery and Outcomes
- Attention Deficit Hyperactivity Disorder
- Biofield Effects and Biophysics
- Ophthalmology and Visual Impairment Studies
- Retinal Diseases and Treatments
- biodegradable polymer synthesis and properties
- Liver Disease Diagnosis and Treatment
- Functional Brain Connectivity Studies
- Tea Polyphenols and Effects
- Diet and metabolism studies
Children's Hospital of Fudan University
2021-2025
Children's Clinical University Hospital
2022
Tsinghua University
1998
A strain of Pseudomonas stutzeri coded 1317 isolated from oil-contaminated soil was found to grow well in glucose and soybean oil as a sole carbon source, respectively. Polyhydroxyalkanoates containing medium chain length monomers hydroxyalkanoates ranging C6 C14 were synthesized up 52% cell dry weight P. stutzri grown on mineral media. In media 10 g l−1 oil, produced 63% polyhydroxyalkanoates mainly novel monomer 3,6-epoxy-7-nonene-1,9 dioic acids making the polyhydroxyalkanoates, together...
Abstract Objective The aim of this study was to investigate the effectiveness an intermittent low‐carbohydrate diet (ILCD) versus calorie restriction (ICR) in young populations and potential mechanisms. Methods Thirty‐four participants aged 9 30 years with cardiometabolic risk were randomized receive a self‐administered 2‐week ILCD (carbohydrate intake ≤ 50 g/d on seven nonconsecutive days) or ICR (500–600 kcal/d for two consecutive days per week). Differences changes obesity measures,...
Gestational hypertension (GH) and preeclampsia (PE) are severe adverse gestational complications. Previous studies supported potential link between elevated liver enzyme levels GH PE. However, given the transient physiological reduction of in pregnancy, little is known whether associations high-normal early pregnancy with PE exist pregnant women. Pregnant women this study came from a sub-cohort Shanghai Preconception Cohort, who were four examined at 9-13 weeks without established diseases,...
Abstract Purpose This study aims to evaluate a combined effect of dietary folic acid intake, multiple genetic polymorphisms in folate metabolism, and other environmental factors on red blood cell (RBC) concentration pregnancy-preparing population. Methods 519 subjects (260 couples) were investigated. Dietary intake was measured by 3-day recalls. 13 Single Nucleotide (SNPs) reported association with one-carbon metabolism including the methylenetetrahydrofolate reductase (MTHFR) C677T A1298C...
As a severe morbidity during pregnancy, the etiology of spontaneous pregnancy loss (SPL) remains largely unknown. Serum glycated hemoglobin (HbA
Myopia is one of the most common eye diseases causing visual impairment and blindness, high prevalence in adolescents remains a major public health concern. Based on clinical studies using optical defocus to regulate ocular growth refractive changes through feedback, we hypothesize that early wearing peripheral myopic defocusing spectacles children with risk myopia may slow process emmetropization even prevent onset by inducing more defocus. The aim this study investigate whether focus-out...
Background and Aim: Serum bilirubin levels are recently shown to be a novel protector of gestational diabetes mellitus (GDM), yet whether they could affected by carbohydrate quality is unclear. We aimed examine the associations between dietary parameters serum during early pregnancy, with further exploration on potential mediating role parameters-GDM pathways. Methods: 260 healthy but overweight or obese gravidae (BMI ≥24 kg/m2) derived from historical cohort in two hospitals China were...
Abstract Background The Peripheral Arterial Tonometry (PAT) technique measured by Endo-PAT™, is recently introduced for peripheral vascular assessment in youth, primarily benefits from its easy and non-invasive operation. However, the value of Endo-PAT as early indicator obesity-related cardiometabolic risk factors remains unclear, with few studies focusing solely on Reactive Hyperemia Index (RHI). A wider coverage algorithms recommended to be applied simultaneously youth. We evaluated...
<sec> <title>BACKGROUND</title> As a severe morbidity during pregnancy, the etiology of spontaneous pregnancy loss (SPL) remains largely unknown. Serum glycated hemoglobin (HbA<sub>1c</sub>) level is an established predictor SPL risk among women with diabetes, but little known about whether such association exists pregnant without diabetes when glycemic levels are within normal range. </sec> <title>OBJECTIVE</title> This study aimed to quantify between maternal...
Background: To quantify the associations of maternal HbA1c and fasting blood glucose (FBG) levels in non-diabetic pregnant women early pregnancy with subsequent spontaneous loss (SPL) risk. Methods: A sub-cohort ongoing Shanghai Preconception Cohort Study involving 9750 FBG examined was included for analysis. SPL diagnosis derived confirmed based on medical records. Generalized linear models were used to risk, reported as risk ratios (RRs) 95% confidence intervals (CIs) after adjustment...