A5074428647- Birth, Development, and Health
- Gestational Diabetes Research and Management
- Obesity, Physical Activity, Diet
- Epigenetics and DNA Methylation
- Cardiovascular Health and Disease Prevention
- Neonatal Respiratory Health Research
- Chemotherapy-induced cardiotoxicity and mitigation
- Childhood Cancer Survivors' Quality of Life
- Congenital Diaphragmatic Hernia Studies
- Cardiovascular Disease and Adiposity
- Blood Pressure and Hypertension Studies
- Hemodynamic Monitoring and Therapy
- Chemotherapy-induced organ toxicity mitigation
- Cardiac tumors and thrombi
- Acute Kidney Injury Research
- Pregnancy and preeclampsia studies
- Bariatric Surgery and Outcomes
- Body Composition Measurement Techniques
- Nutritional Studies and Diet
- Pediatric Hepatobiliary Diseases and Treatments
- Dialysis and Renal Disease Management
- Liver Disease Diagnosis and Treatment
- Genetic Syndromes and Imprinting
- Paraoxonase enzyme and polymorphisms
- Infant Development and Preterm Care
Children's Hospital of Fudan University
2016-2024
Shandong First Medical University
2019-2024
First Affiliated Hospital of Henan University of Science and Technology
2024
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2024
Shandong Provincial QianFoShan Hospital
2018-2023
Shandong University
2018-2019
Weatherford College
2019
This study reevaluated the secular trends of blood pressure and hypertension prevalence in Chinese children adolescents by adjusting for growing body sizes.The population was from China Health Nutrition Survey (1991-2011) included 7358 boys 6881 girls aged 8-17 years. Body size measurements were standardized into z-scores using national references to allow comparisons among different age groups survey Prehypertension rates defined international age-specific height-specific references.SBP DBP...
Low glycemic index (LGI) diet has shown to be effective in reducing maternal and neonatal complications high-risk pregnancies.This trial aimed examine the effectiveness of individualized LGI consultations based on accurate load (GL) assessment tool insulin resistance levels behavior changes overweight obese pregnant women.Overweight women were recruited before 16 weeks gestation randomized arm or control arm. All participants received standard dietary education according Chinese Dietary...
Studies have shown that the effects of maternal nutrition exposure during gestation influence metabolic risk in early life through an epigenetic mechanism. Low glycaemic index (GI) diets benefit both and neonatal gestational outcomes. We hypothesize dietary GI or load (GL) changes pregnancy impact placental DNA methylation, especially insulin resistance-related genes. From a clinical trial overweight pregnant women, 12 subjects who successfully reduced their another whose increased despite...
Abstract The clinical diagnosis of biliary atresia (BA) poses challenges, particularly in distinguishing it from cholestasis (CS). Moreover, the prognosis for BA is unfavorable and there a dearth effective non-invasive diagnostic models detection. Therefore, aim this study to elucidate metabolic disparities among children with BA, CS, normal controls (NC) without any hepatic abnormalities through comprehensive metabolomics analysis. Additionally, our objective develop an advanced model that...
Moderate-to-severe bronchopulmonary dysplasia (msBPD) is a serious complication in preterm infants. We aimed to develop dynamic nomogram for early prediction of msBPD using perinatal factors infants born at <32 weeks' gestation.
Abstract Pediatric elevated blood pressure (BP) and hypertension are usually defined using traditional BP tables at the 90th 95th percentiles, respectively, based on sex, age, height, which cumbersome to use in clinical practice. The authors aimed assess performance of static cut‐points (120/80 mm Hg 130/80 for defining adolescents, respectively; 110/70 120/80 children, respectively) predicting increased arterial stiffness. Using data from five population‐based cross‐sectional studies...
Abstract Rationale: To explore the curative effect of human umbilical cord-derived mesenchymal stem cell (ucMSC) therapy for patients with liver cirrhosis complicated immune thrombocytopenia and refractory Henoch–Schonlein purpura (HSP). Patient concerns: A 12-year-old boy presented to our hospital an 11-month history on skin both lower limbs accompanied by thrombocytopenia. The patient had a repeated swelling painful dorsum pedis, followed redness. Diagnosis: Bone marrow slides showed...
Abstract Rationale: Simpson−Golabi−Behmel syndrome type 1 (SGBS1) is caused by mutations in GPC3 or both and GPC4. Physical manifestations of SGBS1 include fetal overgrowth macrostomia, macroglossia. Subclinical hypothyroidism has never been reported cases. Patient concerns: An 8-days-old boy was referred to our hospital with persistent hypoglycemia special facies. And the infant showed elevated levels thyroid-stimulating hormone (TSH). Free T4 free T3 were normal. Diagnoses: Definitive...
To investigate the distribution of peripheral arterial stiffness, endothelial function and their correlations with cardiovascular risk factors in 7-17 year-olds.Normal weight obese subjects aged years completed data on questionnaires, anthropometric blood biochemical tests, were recruited from a cross-sectional population-based study childhood hypertension Minhang district Shanghai. Automatic waveform analyzer (BP-203RPE-I) Endopat 2000 used to measure stiffness. Endothelial brachial-ankle...
Objective This study aimed to construct and validate a nomogram for predicting cardiovascular mortality (CVM) child, adolescent, adult patients with diffuse large B-cell lymphoma (DLBCL). Materials methods Patients only one primary tumor of DLBCL first diagnosed between 2000 2019 in the SEER database were extracted. We used cumulative incidence function (CIF) evaluate rate CVM. The outcome interest was CVM, which analyzed using competing risk model, accounting death due other causes. total...
Background: The fatal cyclophosphamide cardiotoxicity is associated with high mortality in the adult population, and study of its effects on children represents a gap field. This aimed to evaluate potential global longitudinal strain (GLS) as predictor cardiovascular events among high-dose chemotherapy. Methods: was prospective cohort patients aged 14 years or younger who received (>120 mg/kg) chemotherapy recruited consecutively. Blood collection echocardiography were performed 1 day before...
Abstract Background The Peripheral Arterial Tonometry (PAT) technique measured by Endo-PAT™, is recently introduced for peripheral vascular assessment in youth, primarily benefits from its easy and non-invasive operation. However, the value of Endo-PAT as early indicator obesity-related cardiometabolic risk factors remains unclear, with few studies focusing solely on Reactive Hyperemia Index (RHI). A wider coverage algorithms recommended to be applied simultaneously youth. We evaluated...
Objectives This study aimed to construct and validate smoothed gestational weight centile curves based on preconception status for Chinese pregnant women. Design A retrospective hospital routine data Setting Hospital prenatal care. Population cohort of women with body weights without maternal or neonatal complications (sample 1, n=2992), a non-selective independent sample 2, n=7420), were selected from curve construction validation. Study design Smoothed each week constructed using the LMS...
<sec> <title>BACKGROUND</title> Low glycemic index (LGI) diet has shown to be effective in reducing maternal and neonatal complications high-risk pregnancies. </sec> <title>OBJECTIVE</title> This trial aimed examine the effectiveness of individualized LGI consultations based on accurate load (GL) assessment tool insulin resistance levels behavior changes overweight obese pregnant women. <title>METHODS</title> Overweight women were recruited before 16 weeks gestation randomized arm or control...