A5100462954- Aortic Disease and Treatment Approaches
- Aortic aneurysm repair treatments
- Neonatal Respiratory Health Research
- Respiratory Support and Mechanisms
- Pneumonia and Respiratory Infections
- SARS-CoV-2 and COVID-19 Research
- COVID-19 Clinical Research Studies
- Hip and Femur Fractures
- Gastrointestinal motility and disorders
- COVID-19 and Mental Health
- COVID-19 epidemiological studies
- Respiratory viral infections research
- Congenital Diaphragmatic Hernia Studies
- Oral health in cancer treatment
- Vascular anomalies and interventions
- SARS-CoV-2 detection and testing
- Pelvic floor disorders treatments
- Infectious Aortic and Vascular Conditions
- Kidney Stones and Urolithiasis Treatments
- COVID-19 Impact on Reproduction
- Biomarkers in Disease Mechanisms
- Inflammasome and immune disorders
- Amoebic Infections and Treatments
- Cancer, Hypoxia, and Metabolism
- Injury Epidemiology and Prevention
KK Women's and Children's Hospital
2020-2025
Guangzhou Medical University
2024
Second Affiliated Hospital of Jilin University
2024
Dalian Polytechnic University
2024
Affiliated Hospital of Guangdong Medical College Hospital
2023
Shenzhen Children's Hospital
2023
Duke-NUS Medical School
2016-2022
Changchun University of Chinese Medicine
2022
National University of Singapore
2020-2022
Nanyang Technological University
2021-2022
A well 6-month-old infant with coronavirus disease 2019 (COVID-19) had persistently positive nasopharyngeal swabs up to day 16 of admission. This case highlights the difficulties in establishing true incidence COVID-19, as asymptomatic individuals can excrete virus. These patients may play important roles human-to-human transmission community.
Abstract Transmission risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in schools is unknown. Our investigations, especially preschools, could not detect SARS-CoV-2 transmission despite screening symptomatic and asymptomatic children. The data suggest that children are the primary drivers help inform exit strategies for lifting lockdowns.
Introduction: In this study, a comparison of clinical, epidemiological and laboratory parameters between symptomatic asymptomatic children with SARS-CoV-2 infection was performed. Materials Methods: Data from all confirmed admitted to KK Women’s Children’s Hospital (KKH), Singapore, January May 2020 were analysed. Results: Of the 39 COVID-19 included, 38.5% asymptomatic. Household transmission accounted for 95% cases. The presenting symptoms low-grade fever (54.2%), rhinorrhoea (45.8%), sore...
Data on burden of invasive pneumococcal disease (IPD) are lacking from Southeast Asia. With the introduction higher-valency conjugate vaccines (PCVs), we aim to assess impact PCV into Singapore's National Childhood Immunisation Schedule (NCIS) IPD and serotype replacement. Using surveillance data a single center, compared incidence in children aged <17 years before after NCIS (2000-2009, period 1; 2010-2023, 2). The overall 2000 2023 was 3.9 per 100 000 children. decline between periods 1 2...
Multisystem inflammatory syndrome in children (MIS-C) is a rare with multisystem involvement affecting exposed to COVID-19. This condition rarely reported East Asia and was not detected Singapore until 2021. We present 12 cases of MIS-C diagnosed KK Women's Children's Hospital (KKH) from October 2021 December 2021.We conducted an observational study on fulfilling the Ministry Health criteria for January 2020 KKH. Medical records were reviewed obtain information clinical presentation, disease...
Birth hypoxia causes neonatal mortality and morbidity. Hypoxia/ischemia can facilitate brain damage, causing various kinds of diseases, such as ischemic stroke. It is necessary to understand the potential underlying mechanisms Previous studies revealed involvement thousand one kinase 1 (TAOK1) in many cellular processes.Herein, middle cerebral artery (MCA) occlusion (MCAO) was performed rats establish stroke animal model, cortical neural stem cells from were treated with oxygen-glucose...
Abstract Background Admission hypothermia (AH, < 36.5℃) remains a major challenge for global neonatal survival, especially in developing countries. Baseline research shows nearly 89.3% of very low birth weight (VLBW, 1500 g) infants suffer from AH China. Therefore, prospective multicentric quality improvement (QI) initiative to reduce regional and improve outcomes among VLBW neonates was implemented. Methods The study used sequential Plan—Do—Study—Act (PDSA) approach. Clinical data were...
Given the significant decline in vaccine efficacy against Omicron, development of novel vaccines with specific or broad-spectrum effectiveness is paramount. In this study, we formulated four monovalent based on recombinant spike trimer proteins, along three bivalent vaccines, and five proteins. We evaluated different vaccination regimens eliciting neutralizing antibodies mice through pseudovirus neutralization assays. Following two doses primary immunization D614G, received subsequent...
Bronchopulmonary dysplasia (BPD) is a very common respiratory disease in premature infants, but there still different understanding of the definition BPD. Therefore, this study intended to compare are main clinical results and health economic expenditures under BPD definitions.This included infants who came into neonatal intensive care unit (NICU) from January 2018 2020, were not more than 32 weeks premenstrual age. The consequences analyzed by National Institute Health Human Development...
Abstract Rationale: Simpson−Golabi−Behmel syndrome type 1 (SGBS1) is caused by mutations in GPC3 or both and GPC4. Physical manifestations of SGBS1 include fetal overgrowth macrostomia, macroglossia. Subclinical hypothyroidism has never been reported cases. Patient concerns: An 8-days-old boy was referred to our hospital with persistent hypoglycemia special facies. And the infant showed elevated levels thyroid-stimulating hormone (TSH). Free T4 free T3 were normal. Diagnoses: Definitive...
To evaluate the perioperative clinical efficacy of preoperative human fibrinogen treatment in patients with acute Stanford type A aortic dissection (ATAAD).Data 159 ATAAD who underwent emergency surgical our hospital from January 2019 to December 2020 were retrospectively analyzed. Patients divided into two groups according whether was administered before surgery: group received surgery, while those B did not. The data, postoperative complications related coagulation function, and mortality...
To compare the effects of modified triple-branched stent implantation and frozen elephant trunk technique on quality life (QoL) acute Stanford Type A aortic dissection (AAAD) patients at different follow-up times. Data from 175 AAAD survivors was collected which were divided into two groups according to surgical techniques: (group A): graft implantation; B): trunk. The SF-36 used assess QoL discharge (AD), third postoperative month (POM3), twelfth (POM12). (1) total scores each time both...
You have accessJournal of UrologyInfections/Inflammation/Cystic Disease the Genitourinary Tract: Kidney & Bladder II (PD63)1 May 2024PD63-06 EXPLORING BACTERIAL ROLES IN CALCIUM OXALATE STONE FORMATION THROUGH HIGH-RESOLUTION IMAGING Ava Mousavi, Reyhaneh Nazarian, William C. Schmidt, Karan Thaker, Javier Prieto, Gerard L. Wong, Aaron Celestian, Qian Chen, Jiahui Li, and Kymora B. Scotland MousaviAva Mousavi , NazarianReyhaneh Nazarian SchmidtWilliam Schmidt ThakerKaran Thaker PrietoJavier...
A female infant weighing 530 g was born at 24 weeks of gestation. Antenatal ultrasounds were unremarkable. She intubated and given surfactant birth. Umbilical venous (UV) arterial (UA) catheters inserted through the identified separate vascular orifices. Postinsertion X-ray showed one catheter entering left liver lobe other right atrium (figure 1). The deeper withdrawn but subsequently migrated into hepatic vein 2). Neither a descent to pelvis before ascending, as would have been observed in...
To investigate the correlation between postoperative feeding intolerance and defecation, with a view to carrying out prognostic assessment timely intervention for recovery of gastrointestinal function.The 114 neonates congenital intestinal atresia who underwent primary anastomosis admitted Shenzhen Children's Hospital from January 2014 December 2022 were studied, patients' basic information, intraoperative conditions, hospitalization time retrospectively analyzed.The risk factors after are...