A5102786489- Neonatal Respiratory Health Research
- Congenital Diaphragmatic Hernia Studies
- Congenital Heart Disease Studies
- Infant Development and Preterm Care
- Reproductive Biology and Fertility
- Respiratory Support and Mechanisms
- Pulmonary Hypertension Research and Treatments
- Ovarian function and disorders
- Neonatal and fetal brain pathology
- Congenital heart defects research
- Pregnancy and preeclampsia studies
- Hemodynamic Monitoring and Therapy
- Retinal and Optic Conditions
- Prenatal Screening and Diagnostics
- Assisted Reproductive Technology and Twin Pregnancy
- Cardiovascular Issues in Pregnancy
- Ocular Diseases and Behçet’s Syndrome
- Genetic Syndromes and Imprinting
- Endometriosis Research and Treatment
- Ultrasound in Clinical Applications
- Infant Nutrition and Health
- Neonatal Health and Biochemistry
- Birth, Development, and Health
- Reproductive System and Pregnancy
- Biomarkers in Disease Mechanisms
Shandong University
2019-2023
Shandong First Medical University
2019-2023
Affiliated Hospital of Shandong University of Traditional Chinese Medicine
2021-2023
Shandong Provincial QianFoShan Hospital
2019-2022
Liaocheng People's Hospital
2020
Shandong Provincial Hospital
2020
Weatherford College
2019
Jining First People's Hospital
2018
Birth hypoxia causes neonatal mortality and morbidity. Hypoxia/ischemia can facilitate brain damage, causing various kinds of diseases, such as ischemic stroke. It is necessary to understand the potential underlying mechanisms Previous studies revealed involvement thousand one kinase 1 (TAOK1) in many cellular processes.Herein, middle cerebral artery (MCA) occlusion (MCAO) was performed rats establish stroke animal model, cortical neural stem cells from were treated with oxygen-glucose...
Background Hypothermia is a common problem that associated with increased mortality and morbidity among preterm infants, especially in China. The objective of this study was to evaluate the efficacy targeted quality improvement (QI) project applied hypothermia prevention measures for very-low-birth-weight (VLBW) infants three tertiary neonatal intensive care units (NICUs) Problem Between January 2018 December 2018, we conducted prospective analysis found incidence AH 88.2% VLBW infants....
Abstract Background Admission hypothermia (AH, < 36.5℃) remains a major challenge for global neonatal survival, especially in developing countries. Baseline research shows nearly 89.3% of very low birth weight (VLBW, 1500 g) infants suffer from AH China. Therefore, prospective multicentric quality improvement (QI) initiative to reduce regional and improve outcomes among VLBW neonates was implemented. Methods The study used sequential Plan—Do—Study—Act (PDSA) approach. Clinical data were...
In the present study we aimed to analyze effects of different anesthesia methods on hemodynamics caesarean section, outcomes after section and hormone changes in pregnancy complicated with severe pulmonary arterial hypertension (PAH). A total 75 PAH that were treated Jining First People's Hospital from January 2016 2017 selected. Three groups set according methods, including subarachnoid combined epidural group (group I, n=25), II, n=25) general III, n=25). Effects observed. Sex levels...
Background At present, the relationship between thyrotropin (TSH) and free thyroxine (FT4) in relation to postmenstrual age (PMA) preterm infants is still unclear, there no reliable standard thyroid hormone reference ranges, resulting different diagnostic criteria for congenital hypothyroidism been used by newborn screening programs countries. Objectives To investigate TSH/FT4 PMA very (VPIs) born with gestational (GA) &lt;32 weeks derive function charts based on PMA. Methods A...
Bronchopulmonary dysplasia (BPD) is a very common respiratory disease in premature infants, but there still different understanding of the definition BPD. Therefore, this study intended to compare are main clinical results and health economic expenditures under BPD definitions.This included infants who came into neonatal intensive care unit (NICU) from January 2018 2020, were not more than 32 weeks premenstrual age. The consequences analyzed by National Institute Health Human Development...
Objective: To observe the effect of 2% ganciclovir eye drops on Posner-Schlossman syndrome (PSS) patients with positive cytomegalovirus (CMV) in aqueous humor. Methods: Prospective study. The cases clinically diagnosed as PSS CMV were enrolled from August 2017 to January 2018 at Department Ophthalmology, Eye & ENT Hospital Fudan University. All underwent and serum analysis for by enzyme linked immunosorbent assay polymerase chain reaction. history clinical signs noted, prescribed topical use...
Abstract Rationale: Simpson−Golabi−Behmel syndrome type 1 (SGBS1) is caused by mutations in GPC3 or both and GPC4. Physical manifestations of SGBS1 include fetal overgrowth macrostomia, macroglossia. Subclinical hypothyroidism has never been reported cases. Patient concerns: An 8-days-old boy was referred to our hospital with persistent hypoglycemia special facies. And the infant showed elevated levels thyroid-stimulating hormone (TSH). Free T4 free T3 were normal. Diagnoses: Definitive...
Abstract Objectives Early screening and dynamic monitoring of pulmonary vascular disease (PVD) in bronchopulmonary dysplasia (BPD) high‐risk infants is great clinical significance. Pulmonary artery acceleration time (PAAT) a reliable non‐invasive method for assessing PVD children over 1 year, but to date, few studies have used PAAT assess hemodynamics preterm infants, especially those with BPD. Through the main hemodynamic indicators reflected after birth, this study aimed value evaluating...
Background Transferring blastocysts frozen on day 6 (D6) may adversely affect the pregnancy rate compared with 5 (D5). Moreover, it remains unclear whether delayed embryo transfer affects neonatal birth weight. Methods A retrospective cohort study consisting of 17,127 singleton births from single (FET) cycles, between January 2011 and 2020, was performed including 14,166 D5 2,961 D6. The primary outcomes this were weight incidence small for gestational age (SGA), large (LGA), low (LBW),...
Abstract Background: Hypothermia is still a common problem and associated with increased mortality morbidity in preterm infants, especially China. The objective of this study was to evaluate the efficacy targeted quality improvement (QI) project hypothermia preventive measures very low-birth weight (VLBW) infants 3 tertiary neonatal intensive care unit (NICU) Methods: Based on literature, our preliminary findings needs each unit, team decided focus efforts equipment (transport incubator,...
Pulmonary artery acceleration time (PAAT) is a reliable and non-invasive method for assessing pulmonary hemodynamics. To date, few studies have used PAAT to assess preterm infants, especially those with respiratory distress syndrome (RDS). This study aimed changes in among infants RDS undergoing surfactant (PS) therapy or not, determine its potential effects on the vascular disease (PVD) outcomes of late postnatal period.The risk was reviewed 62 gestational age 26-31 weeks. The receiving PS...
Introduction: Pulmonary artery acceleration time (PAAT) is a reliable and noninvasive method of assessing pulmonary hemodynamics in children adults, but it lacks validity for preterm infants. The aim this study was to assess changes PAAT among infants with neonatal respiratory distress syndrome (NRDS) who are receiving surfactant (PS) therapy, determine its potential significance terms outcomes. Methods: Between January December 2019, 62 gestational age 27–31 weeks, risk NRDS, had been...
Abstract Background: Zishen Yutai Pill (ZYP), a traditional Chinese patent medicine, is often used for the prevention of recurrent miscarriage and threatened abortion. However, ZYP’s beneficial role in embryo quality pregnancy outcomes are unclear. At same time, Bone morphogenetic protein 15 (BMP15) Growth differentiation factor 9 (GDF9) play key roles folliculogenesis. The expression BMP15 GDF9 declined accompany with poorer oocyte poor ovarian responders.The present prospective study...
Objectives — Early screening and dynamic monitoring of pulmonary vascular disease (PVD) in bronchopulmonary dysplasia (BPD) high-risk infants is great clinical significance. Pulmonary artery acceleration time (PAAT) a reliable non-invasive method for assessing PVD children over 1 year, but to date, few studies have used PAAT assess hemodynamics preterm infants, especially those with BPD. Through the main hemodynamic indicators reflected after birth, this study aimed value evaluating early...
Abstract Background: Admission hypothermia (AH, <36.5℃) remains a major challenge for global neonate survival, especially in China. Due to high incidence of reginal AH, we developed prospective multicenter quality improvement (QI) initiative reduce regional AH and evaluate the impact on outcome among VLBW neonates. Methods: The study used sequential Plan - Do Study Act (PDSA) approach. Clinical data were collected prospectively with 5 NICUs from Sino-Northern Neonatal Network (SNN) Bundle...