A5100407484- Wastewater Treatment and Nitrogen Removal
- Water Treatment and Disinfection
- RNA modifications and cancer
- Pharmaceutical and Antibiotic Environmental Impacts
- Membrane Separation Technologies
- Cancer-related gene regulation
- Ammonia Synthesis and Nitrogen Reduction
- MicroRNA in disease regulation
- Cancer-related molecular mechanisms research
- Extracellular vesicles in disease
- Microbial Community Ecology and Physiology
- Heavy metals in environment
- Pharmacological Effects of Natural Compounds
- Circular RNAs in diseases
- Aquaculture disease management and microbiota
- Microbial Fuel Cells and Bioremediation
- Constructed Wetlands for Wastewater Treatment
- interferon and immune responses
- RNA Interference and Gene Delivery
- Thallium and Germanium Studies
- Environmental and Agricultural Sciences
- Metabolomics and Mass Spectrometry Studies
- T-cell and B-cell Immunology
- Birth, Development, and Health
- Traditional Chinese Medicine Analysis
Beijing University of Technology
2016-2025
Hubei University of Medicine
2024
Jilin University
2024
Sichuan Agricultural University
2017-2024
Qiqihar Medical University
2023-2024
Jimei University
2021-2024
Southwest Medical University
2022-2023
Qilu Hospital of Shandong University
2017-2023
Fudan University
2022-2023
Chengdu University of Traditional Chinese Medicine
2023
The present study investigated the association of a C60 water suspension (nC6) with natural organic matter, as soil constituent or dissolved in column, and its effect on antibacterial activity nC60. Sorption nC60 to reduced bioavailability activity, sorption capacity strongly depended content soil. Adsorption aquatic humic substances onto possible subsequent reactions also were found eliminate toxicity at acid concentrations low 0.05 mg/L. These findings indicate that matter environment can...
Human umbilical cord mesenchymal stem cells (huMSCs) can treat primary ovarian insufficiency (POI) related to granulosa cell (OGC) apoptosis caused by cisplatin chemotherapy. Exosomes are a class of membranous vesicles with diameters 30-200 nm that constitutively released eukaryotic cells. mediate local cell-to-cell communication transferring microRNAs and proteins. In the present study, we demonstrated effects exosomes derived from huMSCs (huMSC-EXOs) on cisplatin-induced OGC model in vitro...
Abstract In the past few years, exosomes released from adipose-derived stem cells (abbreviated as ADSCs) have shown promises to provide therapeutic benefits in fields of regenerative medicine. miRNAs, existing exosomes, are endogenous, small noncoding RNAs that play important roles a variety cellular functions and tumor development. Emerging evidences indicated miR-21 is one miRNAs associated with angiogenesis. this study, we identified role ADSCs overexpressing regulating/promoting...
The limitation of current biomarker early stage ovarian cancer and the anatomical location (depths pelvic) make difficult to be detected in stage. Growing evidence shows exosomes as key information transmitters, it carried molecules, such miRNAs, proteins, lipids, double-stranded DNA have been reported promising biomarkers many diseases. However, little is known about protein lipid composition cancer.Here, we report proteomic lipidomic analysis derived from cells (SKOV-3) surface epithelial...
To improve the anti-metastasis effects of honokiol (HNK) on breast cancer, we designed cationic liposomes (Lip) in which HNK was encapsulated into Lip, and its surface modified with negatively charged polysialic acid (PSA-Lip-HNK) for efficient treatment cancer. PSA-Lip-HNK possessed a homogeneous spherical shape high encapsulation efficiency. In vitro 4T1 cell experiments indicated that increased cellular uptake cytotoxicity via endocytosis pathway mediated by PSA selectin receptors....
Do exosomes play a role in the pathogenesis of endometriosis murine model? Exosomes from (EMS) can alternatively activate macrophages and thus contribute to development lesions mice. The endometriosis, an inflammatory disease, possibly involves peritoneal macrophages. are recognized as new communicator among cells key modulator several diseases. We performed vitr vivo experiments demonstrate modulating RAW264.7 (macrophages) were used examine effects on vitro. An experiment was also...
Abstract Background Local ischemia and defective osteogenesis are implicated in the progression of glucocorticoid (GC)-induced osteonecrosis femoral head (ONFH). Recent studies have revealed that exosomes released from adipose-derived stem cells (ASCs) play important roles ONFH therapy. The present study aimed to investigate whether derived miR-378-overexpressing ASCs (miR-378-ASCs-Exos) could promote angiogenesis GC-induced ONFH. Methods In vitro, we investigated osteogenic potential...
Aspirin is thought to exert salutary effects in vascular disease states by inhibiting platelet aggregation. Endothelial activation, accumulation of oxidized low-density lipoprotein (ox-LDL) and intense inflammation also characterize atherosclerotic plaque acute myocardial ischemia. Ox-LDL induces expression lectin-like receptors (LOX-1) on endothelial cells leads the matrix metalloproteinases (MMPs), which destabilize plaque. We hypothesized that aspirin may interfere with LOX-1 subsequent...
It has been suggested that peroxisome proliferator-activated receptor (PPAR)-gamma ligands reduce the development of atherosclerosis and myocardial ischemia-reperfusion injury; both these phenomena are associated with platelet activation. We postulated PPAR-gamma activation would inhibit intra-arterial thrombus formation.Sprague-Dawley rats were fed chow mixed pioglitazone (1 or 10 mg/kg/day) for 7 to days. A filter soaked in 30% FeCl(3) was applied around abdominal aorta study patterns...
Cytosine methylation is one of epigenetic information marked on the DNA sequence. In plants, small interfering RNAs (siRNAs) target homologous genomic sequences for cytosine methylation. This process, known as RNA-directed (RdDM), plays an important role in transposon control, regulation gene expression and virus resistance. this paper, we demonstrate that C2 protein encoded by a geminivirus (beet severe curly top virus, BSCTV) mediated decrease repeat regions promoters ACD6, upstream...
Intrauterine growth retardation (IUGR) is associated with insulin resistance and lipid disorder. Tributyrin (TB), a pro-drug of butyrate, can attenuate dysfunctions in body metabolism. In this study, we investigated the effects TB supplementation on metabolism neonatal piglets IUGR. Eight normal birth weight (NBW) 16 IUGR were selected, weaned 7th day, fed basic milk diets (NBW groups) or supplemented 0.1% tributyrin (IT group, piglets) until day 21 (n = 8). Relative parameters for mRNA...
The role of abundant and rare taxa in modulating the performance wastewater-treatment systems is a critical component making better predictions for enhanced functions such as micropollutant biotransformation. In this study, we compared 16S rRNA genes (rDNA) gene expression an activated-sludge-treatment plant (sequencing batch membrane bioreactor) at two solids retention times (SRTs): 20 5 days. These SRTs were used to influence rates biotransformation nutrient removal. Our results show that...