- Air Quality and Health Impacts
- Climate Change and Health Impacts
- Noise Effects and Management
- SARS-CoV-2 and COVID-19 Research
- Bone health and treatments
- Energy and Environment Impacts
- Bone health and osteoporosis research
- Health disparities and outcomes
- COVID-19 Clinical Research Studies
- Vaccine Coverage and Hesitancy
- Primary Care and Health Outcomes
- Parathyroid Disorders and Treatments
- Tryptophan and brain disorders
- COVID-19 epidemiological studies
- Pharmacogenetics and Drug Metabolism
- Bone and Joint Diseases
- Sepsis Diagnosis and Treatment
- Hemodynamic Monitoring and Therapy
- Acupuncture Treatment Research Studies
- Folklore, Mythology, and Literature Studies
- Clinical Reasoning and Diagnostic Skills
- Mitochondrial Function and Pathology
- Homelessness and Social Issues
- Reproductive Health and Contraception
- Health Sciences Research and Education
University Hospital Galway
2024
University College London
2020-2024
Harvard University
1998-2024
Environmental Health
2024
UK Health Security Agency
2023
Public Health England
2020
Energy Institute
2020
Portland State University
2019
VA Portland Health Care System
2016-2018
Beth Israel Deaconess Medical Center
1997-1998
Although the antiresorptive agent alendronate has been shown to increase bone mineral density (BMD) at hip and spine decrease incidence of osteoporotic fractures in older women, few data are available regarding early prediction long-term response therapy, particularly with regard increases BMD. Examining short-term changes biochemical markers incorporates physiologic therapeutic compliance should provide useful prognostic information for patients. The objective this study was examine whether...
Deprived communities in many cities are exposed to higher levels of outdoor air pollution, and there is increasing evidence similar disparities for indoor pollution exposure. There a need understand the drivers this exposure disparity order develop effective interventions aimed at improving population health reducing inequities. With focus on London, UK, paper assembles examine why PM<sub>2.5</sub>, NO<sub>x</sub> CO may disproportionately impact low-income groups. In particular, five...
Abstract Energy emissions mitigation policies bring co-benefits for health and opportunities to drive sustainable development rapidly transitioning economies in sub-Saharan Africa. Developing methods of quantifying these differing demographic groups is an area interest policymakers support resource allocation efforts. Using synthetic populations three municipalities Kenya, we assessed the impact promote use clean cooking fuels on exposure ambient household air pollution associated age-...
To provide evidence synthesis for faster-paced healthcare decision-making, rapid reviews have emerged as a streamlined alternative to standard systematic reviews. In 2012, the Veterans Affairs Evidence-based Synthesis Program (VA ESP) added support Health Administration (VHA) operational partners' more urgent decision-making needs. VHA partners play substantial role in dissemination of ESP through variety routes, including posting on VA ESP's public website (...
Patients taking suppressive doses of T4 are thought to have accelerated bone loss and increased risk osteoporosis. We therefore randomize 55 patients treatment with pamidronate (APD) 30 mg i.v. every 3 months for 2 yr (APD/T4), or placebo (placebo/T4). had measurements mineral density (BMD) the spine, hip, radius, total body 6 yr. There was no significant at any site in placebo/T4 group. Ninety five percent confidence intervals excluded a rate > 0.89%/yr spine 0.31%/yr hip. When men were...
Abstract Heatwaves have serious impacts on human health and constitute a key concern from anthropogenic climate change. People different individual tolerance for heatwaves or unaccustomed temperatures. Those with epilepsy may be particularly affected by temperature as the electroclinical hallmarks of brain excitability in (inter-ictal epileptiform discharges seizures) are influenced range physiological non-physiological conditions. becoming more common affect excitability. Leveraging...
European countries have included healthcare workers (HCWs) among priority groups for COVID-19 vaccination. We established a multi-country hospital network to measure the SARS-CoV-2 incidence and effectiveness of vaccines HCWs against laboratory-confirmed infection.
Exposure to air pollution can lead negative health impacts, with children highly susceptible due their immature immune and lung systems. Childhood exposure may vary by socio-economic status (SES) differences in both outdoor indoor levels, the latter of which depends on, for example, building quality, overcrowding occupant behaviours; however, estimates typically rely on component only. Quantifying population across SES requires accounting variations time-activity patterns, concentrations,...
The temperature rise and increases in extreme heat events related to global climate change is a growing public health threat. Populations temperate climates, including the UK, must urgently adapt increased hot weather as current infrastructure primarily focusses on resilience cold. As we adapt, care should be taken ensure existing inequalities are reduced. Lessons can learned from regions that experience warmer climates applied adaptation UK. We identified known indicators of heat-health...
Exposure to air pollution can lead negative health impacts, with children highly susceptible due their immature immune and lung systems. Childhood exposure may vary by socio-economic status (SES) differences in both outdoor indoor levels, the latter of which depends on, for example, building quality, overcrowding occupant behaviours. Quantifying population across SES requires accounting variations time-activity patterns, concentrations, concentrations microenvironments that account...
As people in the UK spend 95% of their time indoors, buildings are an important modifier exposure to both non-optimal temperatures and air pollution. High ambient temperature high PM2.5 (particulate matter) concentrations often occur together urban areas. Residential building types prone overheating (e.g. purpose-built flats) also more common Together, this may lead spatial demographic inequalities indoor heat from outdoor sources. By combining simulations (EnergyPlus), a spatially...
Mental disorders are a growing problem worldwide, putting pressure on healthcare systems and wider society. Anxiety depression estimated to cost the global economy US$1 trillion per year, yet only 2% of median government expenditure goes towards mental health. There is evidence linking housing, socio-economic status local environmental conditions with health inequalities. The aim this paper link several open-access datasets at area level (N = 32,844) for England clinical metrics describe...
COVID-19 vaccination recommendations include healthcare workers (HCWs). We measured vaccine effectiveness (CVE) of the autumn 2023 dose against laboratory-confirmed SARS-CoV-2 infection in a prospective cohort study 1,305 HCWs from 13 European hospitals. Overall CVE was 22% (95% CI: −17 to 48), 49% −8 76) before and −11% −84 34) after start BA.2.86/JN.1 predominant circulation. Autumn led moderate-to-low reduction incidence HCWs. Monitoring is crucial for prevention.
Repeated COVID-19 booster vaccination was recommended in healthcare workers (HCWs) to maintain protection. We measured the relative vaccine effectiveness (rVE) of second dose compared first booster, against laboratory-confirmed SARS-CoV-2 infection HCWs.
Purpose: Racial and ethnic disparities in rates of female sterilization, a prominent method contraception, have been consistently observed for decades. Such are also evident subsequent desire reversal the procedure. Additional work is needed to better understand these patterns, particularly given historical context coercive sterilization patterns minority low-income women. Materials Methods: Two cycles National Survey Family Growth data pooled (2011-2013 2006-2010) used estimate odds ratios...
Emerging research demonstrates that acute exercise can improve neutral-based and emotional memory function. The present study extends this emerging line of inquiry by examining the effects on non-emotional prioritized information. A parallel-group, randomized controlled experiment was conducted. experimental group exercised for 15 minutes, while control engaged in a seated, time-matched task. Afterward, participants completed task, involving an immediate delayed recall. There were no...