- Neuropeptides and Animal Physiology
- Stress Responses and Cortisol
- Thyroid Disorders and Treatments
- Hypothalamic control of reproductive hormones
- Regulation of Appetite and Obesity
- COVID-19 Clinical Research Studies
- SARS-CoV-2 and COVID-19 Research
- Antimicrobial Peptides and Activities
- Ion channel regulation and function
- Sleep and Wakefulness Research
- Protein Hydrolysis and Bioactive Peptides
- Vaccine Coverage and Hesitancy
- Peptidase Inhibition and Analysis
- Emergency and Acute Care Studies
- Aldose Reductase and Taurine
- Nicotinic Acetylcholine Receptors Study
- Vector-Borne Animal Diseases
- Pneumonia and Respiratory Infections
- Dialysis and Renal Disease Management
- Diphtheria, Corynebacterium, and Tetanus
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Biochemical Analysis and Sensing Techniques
- Cannabis and Cannabinoid Research
- Sleep and related disorders
- Fatty Acid Research and Health
Red de Investigación en Actividades Preventivas y Promoción de la Salud
2025
Ministerio de Salud
2025
Universitat Internacional de Catalunya
2024
Hospital Sant Joan de Déu Barcelona
2024
Institut de Recerca Sant Joan de Déu
2024
Universidad Nacional Autónoma de México
2001-2017
University of Bari Aldo Moro
2015
The University of Sydney
2015
Background and purpose: Evidence indicates that the endocannabinoid, 2‐arachidonoylglycerol (2‐AG), increases food intake when injected into nucleus accumbens shell (NAcS), thereby potentially activating hypothalamic nuclei involved in regulation. We aimed to evaluate potential orexigenic effects of endocannabinoid anandamide AA5HT, a fatty acid amide hydrolase (FAAH) inhibitor, OMDM‐1, an inhibitor uptake, NAcS, as well effect these treatments on activation nuclei. Experimental approach:...
Dental disease is more extensive in adults with chronic kidney disease, but whether dental health and behaviors are associated survival the setting of hemodialysis unknown.Prospective multinational cohort.4,205 treated long-term hemodialysis, 2010 to 2012 (Oral Diseases Hemodialysis [ORAL-D] Study).Dental as assessed by a standardized examination using World Health Organization guidelines personal oral care, including edentulousness; decayed, missing, filled teeth index; brushing flossing;...
ABSTRACT Background Streptococcus pneumoniae is a nasopharynx coloniser that can invade sterile tissues, causing Invasive Pneumococcal Disease (IPD). Dolosigranulum pigrum and Corynebacterium pseudodiphtheriticum are commensal bacteria commonly isolated from the of healthy children, potentially playing protective role. This study aims to analyse effects D. C. on S. in vitro growth. Methods strains were collected IPD patients carriers Catalonia (2016-2023). child’s nasopharynx. was...
The confirmation of two cases hantavirus pulmonary syndrome (HPS) in the city San Miguel de Tucuman, province is described present study. In 2021, diagnosis patients with HPS no history travel outside was confirmed. infection determined by serology both cases. Case 1 had an unfavorable outcome, confirmed detection specific IgM antibodies for orthohantavirus and identification a serum sample from three days evolution viral genotype, which previously unreported to be circulation Argentina. 2,...
Thyrotropin-releasing hormone (TRH) is released from the median eminence upon neural stimulation such as cold or suckling exposure. Concomitant with cold- suckling-induced release of TRH a rapid and transient increase in expression proTRH mRNA paraventricular nucleus (PVN) hypothalamus. We employed two strategies to determine whether neurons responding exposure are different those suckling. First, we attempted identify marker cellular activation PVN. Cold induced <i>c-fos</i>...
The hypothalamic-pituitary thyroid (HPT) axis modulates energy homeostasis. Its activity decreases in conditions of negative balance but the effects chronic exercise on are controversial and unknown at hypothalamic level. Wistar male rats were exposed for up to 14 days voluntary wheel running (WR), or pair-feeding (PF; 18% food restriction), repeated restraint (RR), a mild stressor. WR RR diminished intake; body weight gain decreased 3 experimental groups, WAT mass serum leptin more...
European countries have included healthcare workers (HCWs) among priority groups for COVID-19 vaccination. We established a multi-country hospital network to measure the SARS-CoV-2 incidence and effectiveness of vaccines HCWs against laboratory-confirmed infection.
Fasting and malnutrition affect the hypothalamus-pituitary-thyroid axis causing secondary hypothyroidism. The aim of this study was to determine effect 48h fasting in rats 4 12 weeks old, 7 food restriction, activity adenohypophysial thyrotropin-releasing hormone (TRH)-degrading ectoenzyme; also, if these conditions altered peptide levels its messenger ribonucleic acid (mRNA) brain areas limbic system. Male Wistar rat brains were excised, frozen dissected for measurement of: (TRH) content by...
COVID-19 vaccination recommendations include healthcare workers (HCWs). We measured vaccine effectiveness (CVE) of the autumn 2023 dose against laboratory-confirmed SARS-CoV-2 infection in a prospective cohort study 1,305 HCWs from 13 European hospitals. Overall CVE was 22% (95% CI: −17 to 48), 49% −8 76) before and −11% −84 34) after start BA.2.86/JN.1 predominant circulation. Autumn led moderate-to-low reduction incidence HCWs. Monitoring is crucial for prevention.
Background Despite growing evidence of reduced invasive and non-invasive pneumococcal disease attributed to public health measures against the COVID-19 pandemic, effect these on carriage remains unclear. This study aimed assess nasopharyngeal among children adults self-confined at home during national lockdown in Spain while identifying predictors children. Methods Household conducted across metropolitan area Barcelona (Spain) between April-June 2020. Nasopharyngeal samples were collected...
Repeated COVID-19 booster vaccination was recommended in healthcare workers (HCWs) to maintain protection. We measured the relative vaccine effectiveness (rVE) of second dose compared first booster, against laboratory-confirmed SARS-CoV-2 infection HCWs.