A5014996579- Vasculitis and related conditions
- Systemic Lupus Erythematosus Research
- Otitis Media and Relapsing Polychondritis
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Atherosclerosis and Cardiovascular Diseases
- Autoimmune Bullous Skin Diseases
- Urticaria and Related Conditions
- Systemic Sclerosis and Related Diseases
- Salivary Gland Disorders and Functions
- Cell Adhesion Molecules Research
- Sarcoidosis and Beryllium Toxicity Research
- Eosinophilic Disorders and Syndromes
- Dermatological and Skeletal Disorders
- Hematological disorders and diagnostics
- Cutaneous lymphoproliferative disorders research
- Dermatology and Skin Diseases
- Lymphoma Diagnosis and Treatment
- Renal Diseases and Glomerulopathies
- Histiocytic Disorders and Treatments
- Inflammatory Myopathies and Dermatomyositis
- Autoimmune and Inflammatory Disorders Research
- Drug-Induced Adverse Reactions
- Nail Diseases and Treatments
- Autoimmune and Inflammatory Disorders
- Myeloproliferative Neoplasms: Diagnosis and Treatment
Hôpital Dupuytren
2016-2025
Université de Limoges
2014-2024
Hôpital Universitaire Dupuytren
2008-2024
Quinnipiac University
2024
CNR de la Résistance aux Antibiotiques
2013-2023
Centre Hospitalier Universitaire de Limoges
2014-2023
Inserm
1997-2023
University Medical Center Groningen
2023
University of Groningen
2023
Cho Ray Hospital
2023
PurposeBy incorporating major developments in genetics, ophthalmology, dermatology, and neuroimaging, to revise the diagnostic criteria for neurofibromatosis type 1 (NF1) establish Legius syndrome (LGSS).MethodsWe used a multistep process, beginning with Delphi method involving global experts subsequently non-NF experts, patients, foundations/patient advocacy groups.ResultsWe reached consensus on minimal clinical genetic diagnosing differentiating NF1 LGSS, which have phenotypic overlap...
Background: Factors implicated in the severity of drug reaction with eosinophilia and systemic symptoms (DRESS) have not been identified.We retrospectively describe analyze severe cases DRESS defined by history intensive care unit admission death due to DRESS.Observations: Of 15 patients recruited France, 14 were admitted 3 died.The culprit drugs already known cause or trigger DRESS: allopurinol, minocycline hydrochloride, anticonvulsants, sulfonamides, antibiotics.Visceral involvement...
Neurofibromatosis type 2 (NF2) and schwannomatosis (SWN) are genetically distinct tumor predisposition syndromes with overlapping phenotypes. We sought to update the diagnostic criteria for NF2 SWN by incorporating recent advances in genetics, ophthalmology, neuropathology, neuroimaging.We used a multistep process, beginning Delphi method involving global disease experts subsequently non-neurofibromatosis clinical experts, patients, foundations/patient advocacy groups.We reached consensus on...
PURPOSE: Most primary cutaneous B-cell lymphomas have an excellent prognosis. However, large (PCLBCLs) of the leg been recognized as a distinct entity with poorer prognosis in European Organization for Research and Treatment Cancer (EORTC) classification. This distinction on basis site has debated. Our aim was to identify independent prognostic factors multicenter series PCLBCL. PATIENTS AND METHODS: The clinical histologic data 145 patients PCLBCL were evaluated. According EORTC...
Objective Findings from the WEGENT trial and other short‐term studies have suggested that azathioprine (AZA) or methotrexate (MTX) could effectively maintain remission of granulomatosis with polyangiitis (Wegener's) (GPA) microscopic (MPA). This study was undertaken to examine whether differences in rates relapse adverse events would appear after discontinuation these 2 maintenance regimens, when assessed over a longer followup period. Methods Long‐term outcomes patients enrolled were...
Previous studies reported a 2- to 17-fold higher risk of aortic complications (dilation or dissection) in patients with giant-cell arteritis (GCA). We aimed determine whether not GCA large-vessel involvement demonstrated by positron emission tomography 18F-fluorodeoxyglucose combined computed (FDG-PET/CT) have complications. conducted retrospective multicenter study between 1995 and 2014. Patients were included if they fulfilled at least 3 American College Rheumatology criteria for GCA, 2...
Objective. Our aim was to describe patients with giant cell arteritis (GCA)–related stroke and compare them a control group of GCA without stroke. Methods. We created retrospective multicenter cohort (1) diagnosed according the American College Rheumatology criteria between 1995 2015, (2) occurring at time diagnosis or within 4 weeks starting therapy. The consisted Results. Forty [21 women (53%), median age 78 (60–91) yrs] GCA-related were included compared 200 patients. Stroke occurred in...
To identify potential risk factors and the yield of routine screens for early detection malignancy associated with dermatomyositis (DM) polymyositis (PM).Retrospective study malignancies in all patients DM or PM followed up between years 1981 2000 a review relationship to malignancy, usefulness various tests examinations search, patients' course.Departments internal medicine dermatology teaching hospital.Forty consecutive adult (33 cases) (7 cases).(1) Rate false-negative results workup...
Objectives. Articular manifestations (AMs) occurred in ∼30–60% of patients with primary SS (pSS). We conducted the current study to describe clinical presentation, specific treatment and report outcome pSS AM a large bicentric French cohort. Methods. Clinical, biological immunological features 419 consecutive were recorded order course point out impact those rheumatological on evolution. Results. A total 188 (172 women, 16 men) exhibited AM. They preceded sicca symptoms 32, simultaneous...
Transformed mycosis fungoides (TMF) large cells may express CD30 antigen, and because of this, the differential diagnosis between CD30-rich TMF primary cutaneous anaplastic large-cell lymphoma (cALCL) be difficult, especially in distinguishing cALCL associated with MF vs. TMF.To find clinical, histological molecular diagnostic features useful for TMF. To analyse compare prognostic value clinical pathological factors these two diseases.We conducted a retrospective study (1999-2012) 32...
Abstract During a meeting in Munich, Germany, presymptomatic attendee with severe acute respiratory syndrome coronavirus 2 infected at least 11 of 13 other participants. Although 5 participants had no or mild symptoms, 6 typical disease, without dyspnea. Our findings suggest hand shaking and face-to-face contact as possible modes transmission.
To report the efficacy and safety of tocilizumab (TCZ) for giant cell arteritis (GCA).A retrospective multicenter study that included 34 patients receiving TCZ GCA.TCZ was effective in all but 6 patients, who still had mild symptoms. Mean glucocorticoid dose tapered. One patient died 3 to stop therapy because severe adverse events. Twenty-three stopped treatment; 8 these experienced relapses after a mean 3.5 ± 1.3 months.TCZ is GCA. However, side effects occur. Whether this treatment has...
To determine whether cutaneous involvement in patients with angioimmunoblastic lymphadenopathy dysproteinemia (AILD) is related to a clonal T-cell proliferation.Retrospective study.University hospitals.Ten AILD and involvement.The receptor-gamma (TCRG)gene rearrangement was studied the use of polymerase chain reaction denaturing gradient gel electrophoresis blood, nodal, skin samples. Skin nodal samples were investigated also for presence Epstein-Barr virus (EBV) RNA by situ hybridization.A...
Objective. To determine the risk factors for permanent visual loss (PVL) in patients with biopsy-proven giant cell arteritis (GCA) and usefulness of clinical practice. Methods. From 1976 through 2015, charts laboratory results 339 GCA were recorded prospectively at time diagnosis. We used multivariable logistic regression analysis to which 24 pretreatment characteristics associated PVL. Results. Visual ischemic manifestations occurred 108 patients, including PVL 53 (16%), bilaterally 15...