A5079500674- Heart Failure Treatment and Management
- Historical Studies of Medieval Iberia
- Historical Art and Architecture Studies
- Medieval and Early Modern Iberia
- IL-33, ST2, and ILC Pathways
- COVID-19 Clinical Research Studies
- Historical Studies on Spain
- SARS-CoV-2 and COVID-19 Research
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Inflammasome and immune disorders
- Business, Education, Mathematics Research
- Acute Myeloid Leukemia Research
- Galectins and Cancer Biology
- Hemodynamic Monitoring and Therapy
- Diabetes Treatment and Management
- Archaeological and Historical Studies
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Cardiac Arrest and Resuscitation
- Diverse Applied Research Studies
- Business, Innovation, and Economy
- Mechanical Circulatory Support Devices
- Historical Studies in Latin America
- Pneumonia and Respiratory Infections
- Genomics and Rare Diseases
Universidad de Murcia
2018-2024
Instituto Murciano de Investigación Biosanitaria
2018-2022
Hospital Universitario Virgen de la Arrixaca
2018-2021
Abstract Background and Aims Acute heart failure (AHF) promotes inflammatory activation, which is associated with worse outcomes. Colchicine has proven effective in other cardiovascular conditions characterized by but never been evaluated the setting of AHF. Methods This multicenter, randomized, double-blind placebo-controlled trial included patients AHF, requiring ≥40 mg intravenous furosemide, regardless their left ventricular ejection fraction (LVEF) inpatient or outpatient setting....
Donation after circulatory death (DCD) represents a promising opportunity to overcome the relative shortage of donors for heart transplantation. However, necessary period warm ischemia is concern. This study aims determine critical time based on in vivo biochemical changes. Sixteen DCD non-cardiac donors, without cardiovascular disease, underwent serial endomyocardial biopsies immediately before withdrawal life-sustaining therapy (WLST), at arrest (CA) and every 2 min thereafter. Samples...
Colchicine has been proposed as a potential therapy in coronavirus disease 2019 (COVID-19) due to their anti-inflammatory actions.
Abstract Sodium-glucose co-transporter-2 inhibitors (SGLT2i) have shown to prevent heart failure progression, although the mechanisms remain poorly understood. Here we evaluated effect of empagliflozin (EMPA, SGLT2i) in cardiac remodeling after myocardial infarction, interplay with diabetes status and role GTP enzyme cyclohydrolase 1 (cGCH1). A rat model (50 mg/kg streptozotocin, i.p.) was subjected infarction left ventricular systolic dysfunction, by ligation anterior descending coronary...
Aims There is a lack of specific studies assessing the impact natriuretic peptide monitoring in post‐discharge management patients with heart failure (HF) and preserved ejection fraction (HFpEF), throughout vulnerable phase following acute HF hospitalization. The NICE study aims to assess clinical benefit incorporating N‐terminal pro‐B‐type (NT‐proBNP) into HFpEF patients. Methods results Individuals admitted (left ventricular >50%) were included multicentre randomized controlled...
Abstract The severity of lung involvement is the main prognostic factor in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Carbohydrate antigen 15-3 (CA 15-3), a marker damage and fibrosis, could help predict prognosis SARS-CoV-2 pneumonia. This was retrospective observational study. CA analyzed blood samples patients consecutively admitted for pneumonia whose were available biobank. Other markers also measured (interleukin 6 [IL6], C-reactive protein [CRP], D-dimer,...
An amendment to this paper has been published and can be accessed via a link at the top of paper.