A5025165666- Heart Failure Treatment and Management
- Cardiac Structural Anomalies and Repair
- Transplantation: Methods and Outcomes
- Cardiac pacing and defibrillation studies
- Viral Infections and Immunology Research
- Respiratory Support and Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Cardiovascular Function and Risk Factors
- Infective Endocarditis Diagnosis and Management
- Mechanical Circulatory Support Devices
- Cardiac Health and Mental Health
- Antimicrobial Resistance in Staphylococcus
- Cardiovascular and exercise physiology
- Cardiac Valve Diseases and Treatments
- Renal function and acid-base balance
- Sarcoma Diagnosis and Treatment
- Erythrocyte Function and Pathophysiology
- Traumatic Brain Injury and Neurovascular Disturbances
- COVID-19 Clinical Research Studies
- Orthopedic Infections and Treatments
- SARS-CoV-2 and COVID-19 Research
- Streptococcal Infections and Treatments
- Sarcoidosis and Beryllium Toxicity Research
- Natural Products and Biological Research
Hospital Universitario Puerta de Hierro Majadahonda
2023-2024
Hospital Universitario 12 De Octubre
2021-2024
Universidad Europea
2023-2024
Centro de Investigación en Red en Enfermedades Cardiovasculares
2019-2024
University of Washington
2024
Hospital General Universitario Gregorio Marañón
2016-2024
Centro de Investigación Biomédica en Red
2021-2024
Hospital Dipreca
2024
Instituto de Salud Carlos III
2023
Jackson Memorial Hospital
2023
We propose a framework for the robust and fully-automatic segmentation of magnetic resonance (MR) brain images called “Multi-Atlas Label Propagation with Expectation–Maximisation based refinement” (MALP-EM). The presented approach is on registration (MAPER), highly performant label fusion (joint fusion) intensity-based refinement using EM. further adapt this to be applicable gross changes in anatomy. account consistent errors by relaxing anatomical priors obtained multi-atlas propagation...
Abstract Background and Aims Acute heart failure (AHF) promotes inflammatory activation, which is associated with worse outcomes. Colchicine has proven effective in other cardiovascular conditions characterized by but never been evaluated the setting of AHF. Methods This multicenter, randomized, double-blind placebo-controlled trial included patients AHF, requiring ≥40 mg intravenous furosemide, regardless their left ventricular ejection fraction (LVEF) inpatient or outpatient setting....
Background: Poor natriuresis has been associated with a poorer response to diuretic treatment and worse prognosis in acute heart failure. Recommendations on how when measure urinary sodium (UNa) are lacking. We aim evaluate UNa quantification after furosemide stress test (FST) capacity predict appropriate decongestion during failure hospitalization. Methods: Patients underwent an FST day-1 of admission, was measured 2 hours after, dividing patients into low or high based the sample median...
Abstract Aims Sacubitril/valsartan is safe when initiated during hospitalization in a clinical trial setting. Its safety real‐life population not stablished. We compared the initiation of sacubitril/valsartan non‐selected population, PIONEER‐HF trial, and outpatients. Methods results Multicentre registry included 527 patients: 100 were started on (19.0%) 427 as outpatients (81.0%). Compared with those pivotal inpatients our cohort older (71 ± 12 vs. 61 14 years; P < 0.001); had more...
Abstract Background Information on infective endocarditis (IE) caused by Cutibacterium spp. is limited and new Duke–International Society for Cardiovascular Infectious Diseases (ISCVID) criteria have not yet been properly assessed. We examined clinical characteristics, outcomes, performance of diagnostic tests valvular cardiac implantable electronic device–related IE (CIED-IE). Methods Data corresponding to all episodes recorded from 2008 2023 in a prospective national cohort including 46...
Staphylococcus aureus prosthetic valve endocarditis (SAPVE) is a serious infection with high mortality. The main objective of this study was to identify factors associated in-hospital
Dyspnoea is a disabling symptom in patients admitted with heart failure (HF) and respiratory diseases (RD). The main aim of this study to evaluate its intensity at admission discharge the relation quality life. We also describe management, intensity, evolution HF RD.In descriptive, cross-sectional study, we included prospectively all decompensated chronic obstructive pulmonary disease (COPD)/pulmonary fibrosis during 4 months. Surveys quantifying dyspnoea (Numerical Rating Scale 1-10) life...
Corbetta JP, Weller S, Bortagaray JI, Durán V, Burek C, Sager Lopez JC. Ureteral replacement with appendix in pediatric renal transplantation. Abstract: necrosis is an uncommon complication following RT which can adversely affect outcome. Even though authors agree that the native ureter ought to be preserved, there are cases graft function only salvaged by ureteral substitution. The scant references literature on use of for left children prompted us report two whom technique was employed and...
<b><i>Background:</i></b> Chronic obstructive pulmonary disease (COPD) affects up to 65 million people worldwide, and COPD exacerbation causes tissue damage subsequent loss of lung function. It is a multifactorial event in which respiratory infections are involved, but little known about its dynamics. <b><i>Objectives:</i></b> The objective our study was determine the microbiome composition during an post-stabilization....
Abstract Background and Methods Heart transplant recipients (HTr) have a higher probability of suffer from severe coronavirus disease‐2019 (COVID‐19) in comparison to general population, but their risk has changed over the course pandemic relation various factors. We conducted prospective study including all HTr at COVID‐19 tertiary center between February 2020 October 2022. The aim was analyze how prognosis (incidence pneumonia mortality) evolved time, contextualizing variants, vaccination,...
Immunotherapy targeting ganglioside antigens is a powerful tool for the treatment of high risk neuroblastoma. However, only with anti-GD2 antibodies has been used in clinical practice and other options may be pursued. We report use racotumomab, an anti-idiotype vaccine against N-glycolyl neuraminic acid (NeuGc)- containing gangliosides, eliciting immune response child relapsed neuroblastoma expressing NeuGcGM3 ganglioside.
Management of patients with refractory congestion, is one the most important challenges in field heart failure (HF). Diuretic therapy remains widely used to achieve euvolemia. However, some experience fluid overload despite use high-dose diuretics and new strategies overcome diuretic resistance are needed.We report an 85 years-old male patient admitted for decompensated HF persistent tissue (peripheral edema) more than two weeks high dose intravenous furosemide combination other diuretics....
<title>Abstract</title> <bold>Purpose</bold>. <italic>Staphylococcus aureus</italic> prosthetic valve endocarditis (SAPVE) is a serious infection with high mortality. The main objective of this study was to identify factors associated in-hospital <bold>Methods</bold>. From January 2008 December 2021, consecutive patients from Spanish cohort infective definitive diagnosis SAPVE were analyzed. <bold>Results</bold>. During the period, 219 cases diagnosed, which accounted for 16.7% total 1309...
Abstract Background and Aims GLP-1 receptor agonists are antihyperglycemic drugs that have shown an interesting cardio nephroprotective effect beyond glycemic control also induce weight loss, which is likely a facilitating element in the renal cardioprotection of patients with elevated BMI. Patients cardiorenal syndrome often approached as particularly complex cases, can lead to underutilization certain therapeutic groups. We analyzed use semaglutide followed CRU Puerta de Hierro University...