A5087056892- Global trade and economics
- Systemic Lupus Erythematosus Research
- T-cell and B-cell Immunology
- Economic Growth and Productivity
- International Business and FDI
- Monoclonal and Polyclonal Antibodies Research
- Global Financial Crisis and Policies
- Diverse Aspects of Tourism Research
- Global Trade and Competitiveness
- Regional Development and Policy
- Energy, Environment, Economic Growth
- Economic Policies and Impacts
- Monetary Policy and Economic Impact
- Immune Cell Function and Interaction
- Complement system in diseases
- Chronic Lymphocytic Leukemia Research
- Natural Resources and Economic Development
- Linguistic Variation and Morphology
- Philippine History and Culture
- Lexicography and Language Studies
- Global Energy and Sustainability Research
- Geothermal Energy Systems and Applications
- Culture, Economy, and Development Studies
- Economic Theory and Policy
- Banking stability, regulation, efficiency
University of Akureyri
2019-2024
National University Hospital of Iceland
2000-2022
University of Iceland
2005-2017
Bifröst University
2014
Icelandic Tourism Research Centre
2012
University College Dublin
2010
University of Copenhagen
2010
Uppsala University
2006-2010
Reykjavík University
2004-2008
Center for Rheumatology
2005-2006
Objectives To find causal genes for rheumatoid arthritis (RA) and its seropositive (RF and/or ACPA positive) seronegative subsets. Methods We performed a genome-wide association study (GWAS) of 31 313 RA cases (68% seropositive) ~1 million controls from Northwestern Europe. searched outside the HLA-locus through effect on coding, mRNA expression in several tissues levels plasma proteins (SomaScan) did network analysis (Qiagen). Results found 25 sequence variants overall, 33 2 RA, altogether...
The objective is to analyse if international trade affected by different national cultures. International of 21 World Bank listed countries estimated as function the Hofstede cultural dimensions, gross domestic product and population. First, we estimate combined culture dimensions find significant positive effects on countries' trade. Secondly, decompose each separate dimension trade, finding only MAS significantly affect We additional equation versions account for occasional restrictions...
This study explores the characteristics that influence adoption of social responsibility by small and medium-sized enterprises (SMEs) its potential link to innovation. The present employs a qualitative multi-case methodology in order explore SME perspectives on stakeholder influence. exploration is conducted through medium semi-structured interviews with ten representatives. In-depth analysis within across cases reveals clear patterns. findings highlight availability resources as significant...
Abstract Objective A genetic polymorphism in the programmed death 1 (PD‐1) gene encoding coinhibitory PD‐1 immunoreceptor, PD‐1.3A, is associated with systemic lupus erythematosus (SLE). The aim of this study was to assess receptor expression patients SLE, comparison relatives and unrelated healthy controls, identify correlations lower levels PD‐1.3A genotype. Methods Patients patients' relatives, control subjects from Iceland Sweden were studied. Peripheral blood mononuclear cells (PBMCs)...
Fixed costs play a crucial role in current models of foreign direct investment (FDI), yet they are almost entirely ignored empirical treatments FDI. We fill this gap by using 1989–2001 panel FDI flows into Iceland to examine the determinants fixed for multinational firms and how these influence aggregate patterns investment. Our additions research field include usage several natural-resource variables, analysis data on initial entry developed country. use Heckman two-step procedure, which...
This research seeks to analyze the S-shape of Butler's tourist area cycle evolution in order capture maximum level. It is first time this type economic regression modeling performed for evolution, referred as tourism life (TALC) model. Also, very applied forecast a potential peak inbound tourists particular country and sample countries. To non-monotonic relationship cycle, fifth-degree polynomial put forward, accounting government, banks, roads, skilled labor, Internet application. Results...
Abstract. The paper highlights the increased international trade and discussion in recent years of digital currencies, also known as virtual currencies or cryptocurrencies, including bilateral coin bitcoin (BTC). Scholars have emphasised need to consider different preconditions, focusing primarily on domestic perspectives payment intermediation within individual countries. inclusion global is motivated by recognition that time playing an increasingly important role dynamics. presented...
Objective To evaluate the production of interleukin-10 (IL-10) as well levels IgG and antinuclear antibodies (ANA) in systemic lupus erythematosus (SLE) patients their first-degree relatives spouses Icelandic SLE multicase families. Methods IL-10 was studied by enzyme-linked immunospot assay freshly isolated peripheral blood mononuclear cells. Total ANA were also investigated. Subjects consisted 23 47 9 ethnically matched a group healthy controls. A separate study investigated 12 (also from...
Abstract In an effort to identify rare alleles associated with SLE, we have performed whole exome sequencing of the most distantly related affected individuals from two large Icelandic multicase SLE families followed by Ta targeted genotyping additional relatives. We identified multiple likely pathogenic variants in nineteen genes co-segregating disease through generations. Gene co-expression and protein-protein interaction analysis a network highly connected comprising several loci...
Does higher value-added tax (VAT) impact tourism demand in Europe? The research provides unique World Bank data estimation of the marginal and nominal effects on number tourists visiting Europe. sample includes listed by from 1995 to 2016, also VAT Europe trade association hotels, restaurants cafes HOTREC is applied capture industry. Findings indicate that increase form not influence tourist inflow Also, findings do 'close maturity' be more sensitive than 'still growth path' countries,...
Abstract Picture a small open economy, alone in the middle of Atlantic Ocean and highly dependent on trade with NAFTA EU. How important are these trading blocs to country’s exports? significant is isolation size, how do affect export sectors? Typically, volume significantly impacted by economic size exporting country, but this case it not. This suggests that exports from remote economies driven different factors than large economies. The data analysed using unique transformation gravity...
A meta-analysis of publicly available summary statistics on multiple sclerosis combined with three Nordic cohorts (21,079 cases, 371,198 controls) revealed seven sequence variants associating sclerosis, not reported previously. Using polygenic risk scores based public outside the major histocompatibility complex region we quantified genetic overlap between common autoimmune diseases in Icelanders and identified disease clusters characterized by autoantibody presence/absence. As...
This research focuses on how cultural and geographical distance affect trade. The question is whether UK exports are similarly affected by Hofstede national culture distance. OECD data applied to the United Kingdom's as well also accounts for trading countries' economic size, their market in order account economies of scale. Results indicate that more impacted than between its main partners.
<h3>OBJECTIVE</h3> To perform an exploratory analysis of the relative contribution single MHC genes to pathogenesis systemic lupus erythematosus (SLE) in a homogenous white population. <h3>METHODS</h3> class II alleles and C4 allotypes were determined 64 SLE patients ethnically matched controls. HLA-DR DQ typing was performed by polymerase chain reaction amplification with sequence specific primers. agarose gel electrophoresis. <h3>RESULTS</h3> The frequency C4A*Q0 significantly higher than...
This research looks at how foreign direct investment (FDI) in a small open economy compares with that of larger countries. I apply several specifications the knowledge-capital model to unique FDI data from isolated country Iceland, allowing for comparison previous analysis and similarly economies. Using this together other techniques, seek explain determinants by geography, economic size skilled labor availability. The results these show popular do not accurately predict effects case.
International hospitality investment is a key indicator of tourism's growing importance, and the question what drives investment. This research compares Iceland Norway to Nordic countries, range OECD countries. The establishes through econometric modeling how foreign direct in industry driven by factors such as economic market size headquarters home country, value added tax increase, skilled labor compared that host country. Increased understanding on determining this growth from available...
The objective of this study was to evaluate apoptosis and production IL-10 in SLE patients, their spouses first-degree relatives Icelandic multicase families. Previously, increased has been found all three groups. As induce SLE, the percentage lymphocytes undergoing evaluated, as well possible correlation between production. Apoptosis were studied patients (n = 12) from families a matched control group healthy individuals 10). proportion T B at 0, 24, 48 72 h detected by flow cytometry using...