A5051064555- Dialysis and Renal Disease Management
- Renal Transplantation Outcomes and Treatments
- Chronic Kidney Disease and Diabetes
- Diabetes Management and Research
- Renal Diseases and Glomerulopathies
- Diabetes Treatment and Management
- Central Venous Catheters and Hemodialysis
- Diabetes and associated disorders
- Health Systems, Economic Evaluations, Quality of Life
- Organ Donation and Transplantation
- Healthcare cost, quality, practices
- Neurological and metabolic disorders
- Muscle and Compartmental Disorders
- Pharmacological Effects and Toxicity Studies
- Organ Transplantation Techniques and Outcomes
- Acute Kidney Injury Research
- Neurological Complications and Syndromes
- Healthcare Systems and Public Health
- Blood Pressure and Hypertension Studies
- Innovation Policy and R&D
- Acute Ischemic Stroke Management
- Pneumocystis jirovecii pneumonia detection and treatment
- Pregnancy and Medication Impact
- Hormonal Regulation and Hypertension
- HIV/AIDS Research and Interventions
Helsinki University Hospital
2014-2025
Finnish Institute for Health and Welfare
2024
University of Helsinki
2017-2024
Finnish Cancer Registry
2013-2024
Hospital District of Helsinki and Uusimaa
2023
Lapland Central Hospital
2014
The European Renal Association (ERA) Registry collects data on kidney replacement therapy (KRT) in patients with ESKD. This paper is a summary of the ERA Annual Report 2020, also including comparisons among primary renal disease (PRD) groups.Data were collected from 52 national and regional registries 34 countries bordering Mediterranean Sea: 35 18 providing individual level 17 aggregated data. Using this data, KRT incidence prevalence, transplantation rates, expected remaining lifetimes...
This article presents a summary of the 2017 Annual Report European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry describes epidemiology renal replacement therapy (RRT) for end-stage disease (ESRD) in 37 countries.The ERA-EDTA received individual patient data on patients undergoing RRT ESRD from 32 national or regional registries aggregated 21 registries. The incidence prevalence RRT, kidney transplantation activity survival probabilities these were...
ABSTRACT Background The aim of this study was to identify trends in total, deceased donor (DD) and living (LD) kidney transplantation (KT) rates European countries. Methods Renal Association (ERA) Registry the Global Observatory on Donation Transplantation (GODT) databases were used obtain number KTs individual countries between 2010 2018. General population counts obtained from Eurostat or national bureaus statistics. KT rate per million (p.m.p.) average annual percentage change (APC)...
ABSTRACT Background The European Renal Association (ERA) Registry collects data on kidney replacement therapy (KRT) in patients with end-stage disease (ESKD). This paper is a summary of the ERA Annual Report 2021, including comparison across treatment modalities. Methods Data was collected from 54 national and regional registries 36 countries, which 35 18 countries contributed individual patient 19 aggregated data. Using this data, incidence prevalence KRT, transplantation rates, survival...
OBJECTIVE To investigate how risk of end-stage renal disease (ESRD) among patients with type 1 diabetes has changed over time and further the is affected by age, sex, period diagnosis diabetes. RESEARCH DESIGN AND METHODS A cohort including all <30 years old diagnosed in Finland 1965–2011 was followed until start replacement therapy, death, or end follow-up at 2013. Altogether, 29,906 were included. The main outcome cumulative ESRD, accounting for death as a competing risk. RESULTS up...
The aims of this study were to determine the frequency dialysis and kidney transplantation estimate regularity comprehensive conservative management (CCM) for patients with failure in Europe. This uses data from ERA-EDTA Registry. Additionally, our included supplemental Armenia, Germany, Hungary, Ireland, Kosovo, Luxembourg, Malta, Moldova, Montenegro, Slovenia additional Israel, Italy, Slovakia using other information sources. Through an online survey, responding nephrologists estimated CCM...
ABSTRACT Background The aim of this study was to describe the trends in incidence, prevalence and survival patients on kidney replacement therapy (KRT) for end-stage disease (ESKD) across Europe from 2008 2017. Methods Data renal registries 9 countries 16 regions that provided individual patient data ERA Registry 2017 were included. These cover 34% general population Europe. Crude standardized incidence per million (pmp) determined. Trends over time studied using Joinpoint regression....
Home dialysis has been associated with better patient survival compared to in-center hemodialysis. Finland over 40 years of experience home dialysis. Despite sustained efforts, the prevalence decreased in last decade. We aimed explore barriers expanding treatments from healthcare providers' and patients' perspectives. This is qualitative research, based on an electronic semi-structured survey directed nephrologists, nephrology nurses, associations. The development contemplated main shown a...
OBJECTIVE To estimate long-term cumulative risk of end-stage renal disease (ESRD) after diagnosis type 2 diabetes. RESEARCH DESIGN AND METHODS This nationwide population-based inception cohort study included 421,429 patients with diabetes diagnosed in 1990–2011; were followed until the end 2013. Data linkage between several national health care registers Finland, covering 100% population, enabled inclusion almost all inhabitants who started taking medication or hospitalized for Cumulative...
OBJECTIVE Risks of end-stage renal disease and premature death in patients with type 1 diabetes have declined over the past decades. Data on survival receiving replacement therapy (RRT) are, however, limited. We investigated whether RRT has improved time improvement can be attributable to progress dialysis treatment or care. RESEARCH DESIGN AND METHODS An incident cohort all (n = 1,604) starting chronic Finland between 1980 2005 were followed until end follow-up 31 December 2007. The control...
<h3>Introduction</h3> Mortality risk of patients with end-stage renal disease (ESRD) is highly elevated. Methods to estimate individual mortality are needed provide individualized care and manage expanding ESRD populations. Many prediction models exist but have shown deficiencies in model development (data comprehensiveness, validation) practicality. Therefore, our aim was design 2 easy-to-apply for 1- 2-year all-cause starting long-term replacement therapy (RRT). <h3>Methods</h3> We used...
During the past decades, improvements in prevention and management of myocardial infarction, stroke, pulmonary embolism have led to a decline cardiovascular mortality general population. However, it is unknown whether patients receiving dialysis also benefited from these improvements.To assess rates for large cohort European compared with population.In this study, adult who started between 1998 2015 11 countries providing data Renal Association Registry were followed up 3 years. Data...
BackgroundStudies on dialysis modality and survival have shown conflicting results, mostly due to insufficient varying control of confounding factors. Using comprehensive data a well-defined patient cohort, we therefore investigated the association with chronic renal replacement therapy (RRT) whether this varies between subgroups patients.
Objectives Infections are the most common non-cardiovascular cause of death among dialysis patients. Earlier studies have shown similar or higher risk infectious complications in peritoneal (PD) compared to hemodialysis (HD) patients, but comparisons home HD patients been rare. We investigated severe infections after start continuous ambulatory PD (CAPD) and automated (APD) as HD. Methods All adult (n = 536), who were on at day 90 from starting kidney replacement therapy (KRT) between 2004...
ABSTRACT Background The aim of this study was to provide an overview age, sex and primary renal disease (PRD) distribution among first kidney transplant recipients across Europe. Method European Renal Association (ERA) Registry database used obtain data on patients aged 20 years or older receiving their between 2010 2019 from 12 countries. numbers percentages in each PRD group were calculated by country, donor type year. Results In total, 99 543 adults received a transplant. Overall, 23% the...
ABSTRACT Background Several studies have shown superior survival of patients on home haemodialysis (HD) compared with peritoneal dialysis (PD), but automated PD (APD) and continuous ambulatory (CAPD) not been considered separately. As APD allows larger fluid volumes may be more efficient than CAPD, we primarily patient between HD. Methods All adult who started kidney replacement therapy (KRT) 2004 2017 in the district Helsinki-Uusimaa Finland were one modalities at 90 days from starting KRT...
Key Points We observed a comparable cumulative incidence of major adverse cardiovascular event (MACE) in in-center hemodialysis (IC-HD) and continuous ambulatory peritoneal dialysis (PD) patients, which was higher than automated PD home patients. After adjustment for confounders, there no difference risk MACE between patients on modalities IC-HD. Compared with IC-HD, associated lower among female male Background Among events are the leading cause death. Little is known about how frequency...
The incidence of renal replacement therapy (RRT) in the general population ≥75 years age varies considerably between countries and regions Europe. Our aim was to study characteristics survival elderly RRT patients find explanations for differences incidence. Patients at onset 2010–2013 from 29 national or regional registries providing data European Renal Association–European Dialysis Transplant Association Registry were included. Chi-square Mann–Whitney U tests used assess variation patient...
The number of elderly patients on renal replacement therapy (RRT) is increasing. survival and quality life these may be lower if they have multiple comorbidities at the onset RRT. aim this study was to explore whether effect similar in RRT compared with younger ones.Included were 9333 ≥80 years age 48 352 20-79 starting between 2010 2015 from 15 national or regional registries submitting data European Renal Association-European Dialysis Transplantation Association Registry. Patients followed...
Estimated glomerular filtration rate (eGFR) is widely used in follow-up and assessment of patients before start chronic renal replacement therapy (RRT). Reported data on impact eGFR decline pattern during pre-dialysis phase consequent survival RRT are, however, non-existent. Using the database Finnish Registry for Kidney Diseases, we conducted a cohort study all incident adult ( n = 457) entering Finland 1998, with until 31 December 2008. We included those 319) three serum creatinine...
Background Type 2 diabetic (T2DM) patients on renal replacement therapy (RRT) seldom receive a kidney transplant, which is partly due to age and comorbidities. Adjusting for case mix, we investigated whether T2DM have equal opportunity transplantation compared other dialysis, survival after comparable. Methods Patients who entered RRT in Finland 2000–2010 (n = 5419) were identified from the Finnish Registry Kidney Diseases followed until end of 2012. Of these, 20% had T2DM, 14% type 1...
Abstract Background Necrotizing myopathies and muscle necrosis can be caused by immune-mediated mechanisms, drugs, ischemia, infections, differential diagnosis may challenging. Case presentation We describe a case of diabetic myonecrosis complicated pyomyositis abscess Escherichia coli . A white woman in her late forties was admitted to the hospital with 1.5 week history bilateral swelling, weakness, mild pain lower extremities inability walk. She had type 1 diabetes retinopathy, neuropathy,...
ABSTRACT Background Young adults starting kidney replacement therapy (KRT) during childhood and reaching their 18th birthday (i.e. adult survivors of KRT) form a challenging population interest to nephrologists treating adults, as this period there will be transition renal centres. Nonetheless, few studies have focused on the epidemiology KRT in group. We aimed provide an update these patients’ characteristics, treatment history, graft patient survival, report 5-year prognosis expected...