Jade Yu Cheng
A5015670946- Genetic and phenotypic traits in livestock
- Genetic diversity and population structure
- Genomics and Phylogenetic Studies
- Genetic Mapping and Diversity in Plants and Animals
- Forensic and Genetic Research
- melanin and skin pigmentation
- Race, Genetics, and Society
- Indigenous Studies and Ecology
- Genetic Associations and Epidemiology
- Environmental DNA in Biodiversity Studies
- Molecular Biology Techniques and Applications
- Bayesian Methods and Mixture Models
- Adipose Tissue and Metabolism
- Microbial infections and disease research
- Herpesvirus Infections and Treatments
- Cancer-related molecular mechanisms research
- Animal Disease Management and Epidemiology
- Forensic Anthropology and Bioarchaeology Studies
- Evolution and Genetic Dynamics
- Skin Protection and Aging
- Genome Rearrangement Algorithms
- Pleistocene-Era Hominins and Archaeology
- High Altitude and Hypoxia
- Climate Change Communication and Perception
- Nutritional Studies and Diet
Aarhus University
2015-2025
Walt Disney (United States)
2025
University of Copenhagen
2016-2021
University of California, Berkeley
2016-2021
Lundbeck Foundation
2019-2021
Lundbeck (Denmark)
2021
Natural History Museum Aarhus
2016-2019
Genomic studies of endangered species provide insights into their evolution and demographic history, reveal patterns genomic erosion that might limit viability, offer tools for effective conservation. The Iberian lynx (Lynx pardinus) is the most felid a unique example on brink extinction.
Locating myxomatosis resistance Myxomatosis is a viral infection that was deliberately introduced from American cottontail rabbits into European rabbit populations to control their population. Over the past 60 years or so, similar variants have emerged in parallel United Kingdom, France, and Australia. Alves et al. discovered basis for this polygenic, with selection converging on several host immunity proviral alleles (see Perspective by Miller Metcalf). Interestingly, it now seems virus...
We analyzed genome sequences from 6 baboon species and found evidence of ancient recent hybridization among divergent species.
Denmark has played a substantial role in the history of Northern Europe. Through nationwide scientific outreach initiative, we collected genetic and anthropometrical data from ∼800 high school students used them to elucidate makeup Danish population, as well assess polygenic predictions phenotypic traits adolescents. We observed remarkable homogeneity across different geographic regions, although could still detect weak signals structure reflecting country. presented genomic affinity with...
Structure methods are highly used population genetic for classifying individuals in a sample fractionally into discrete ancestry components.We introduce new optimization algorithm the classical STRUCTURE model maximum likelihood framework. Using analyses of real data we show that method finds solutions with higher likelihoods than state-of-the-art same computational time. The is also applicable to models based on genotype likelihoods, can account uncertainty genotype-calling associated Next...
One of the most powerful and commonly used approaches for detecting local adaptation in genome is identification extreme allele frequency differences between populations. In this article, we present a new maximum likelihood method finding regions under positive selection. It based on Gaussian approximation to changes it incorporates admixture The can analyze multiple populations simultaneously retains power detect selection signatures specific ancestry components that are not representative...
Abstract The Viking maritime expansion from Scandinavia (Denmark, Norway, and Sweden) marks one of the swiftest most far-flung cultural transformations in global history. During this time (c. 750 to 1050 CE), Vikings reached western Eurasia, Greenland, North America, left a legacy that persists till today. To understand genetic structure influence expansion, we sequenced genomes 442 ancient humans across Europe Greenland ranging Bronze Age 2400 BC) early Modern period 1600 with particular...
Abstract One of the most powerful and commonly used methods for detecting local adaptation in genome is identification extreme allele frequency differences between populations. In this paper, we present a new maximum likelihood method finding regions under positive selection. The based on Gaussian approximation to changes it incorporates admixture can analyze multiple populations simultaneously retains power detect selection signatures specific ancestry components that are not representative...
Abstract Interspecific hybridization is recognized as a widespread phenomenon but measuring its extent, directionality, and adaptive importance in the evolution of species remain challenging. Polar bears possess unique adaptations to life on Arctic sea ice, whereas their closest relatives -brown - are boreal subarctic generalists. Despite largely non-overlapping modern distributions, genomic evidence demonstrates ancient admixture between these species. Here, we analyze new genomes from...
With full genome data from several closely related species now readily available, we have the ultimate for demographic inference. Exploiting these genomes, however, requires models that can explicitly model recombination along alignments of chromosomal length. Over last decade a class models, based on sequential Markov coalescence combined with hidden has been developed and used to make inference in simple scenarios. To move forward more complex modelling need better automated ways...
Scientific outreach delivers science to the people. But it can also deliver people science. In this work, we report our experience from a large-scale public engagement project promoting genomic literacy among Danish high school students with additional benefit of collecting data for studying genetic makeup population. Not only did confirm that have great interest in their past, but were gratified see that, right motivation, adolescents provide high-quality studies.
Abstract Motivation Structure methods are highly used population genetic for classifying individuals in a sample fractionally into discrete ancestry components. Contribution We introduce new optimization algorithm of the classical model maximum likelihood framework. Using analyses real data we show that finds higher values than state-of-the-art method same computational time. also present estimating trees from components using Gaussian approximation. coalescence simulations modeling...