A5075482622- Gut microbiota and health
- Food composition and properties
- Diet and metabolism studies
- Probiotics and Fermented Foods
- Microbial Metabolites in Food Biotechnology
- Nuts composition and effects
- Digestive system and related health
- Polysaccharides Composition and Applications
- Polysaccharides and Plant Cell Walls
- Agriculture Sustainability and Environmental Impact
- Wheat and Barley Genetics and Pathology
- Gastrointestinal motility and disorders
- HIV-related health complications and treatments
- Enzyme Production and Characterization
- Bee Products Chemical Analysis
- Clostridium difficile and Clostridium perfringens research
- Coconut Research and Applications
- Nutrition and Health in Aging
- Nanocomposite Films for Food Packaging
- Microbial Community Ecology and Physiology
- Material Properties and Processing
- Diet, Metabolism, and Disease
- Phytase and its Applications
- Biochemical Analysis and Sensing Techniques
- Celiac Disease Research and Management
Necmettin Erbakan University
2022-2025
Ordu University
2018-2025
Yenişehir Hospital
2024
Purdue University West Lafayette
2014-2021
Texas A&M University
2015
Epidemiological studies propose a protective role for dietary fiber in colon cancer (CRC). One possible mechanism of is its fermentation property the gut and ability to change microbiota composition function. Here, we investigate mixture polyposis elucidate potential mechanisms using TS4Cre × cAPCl°x468 mice. Stool profiling was performed, while functional prediction done PICRUSt. short-chain fatty acid (SCFA) metabolites were measured. Histone acetylation expression SCFA butyrate receptor...
When presented with nutrient mixtures, several human gut Bacteroides species exhibit hierarchical utilization of glycans through a phenomenon that resembles catabolite repression. However, it is unclear how closely these observed physiological changes, often measured by altered transcription glycan genes, mirror actual depletion. To understand the prioritization strategies two related symbionts, ovatus and thetaiotaomicron, we performed series time course assays in which both were...
Abstract Background Variability in the health effects of dietary fiber might arise from inter-individual differences gut microbiota’s ability to ferment these substrates into beneficial metabolites. Our understanding what drives this individuality is vastly incomplete and will require an ecological perspective as microbiomes function complex inter-connected communities. Here, we performed a parallel two-arm, exploratory randomized controlled trial 31 adults with overweight class-I obesity...
Summary The capability to maintain cell wall integrity is critical for plants adapt unfavourable conditions. l ‐Arabinose (Ara) a constituent of several polysaccharides and many wall‐localised glycoproteins, but so far the contribution Ara metabolism abiotic stress tolerance still poorly understood. Here, we report that mutations in MUR 4 (also known as HSR 8 ) gene, which required biosynthesis UDP ‐Ara p Arabidopsis, led reduced root elongation under high concentrations NaCl, KC l, Na NO 3...
Though the physical structuring of insoluble dietary fiber sources may strongly impact their processing by microbiota in colon, relatively little mechanistic information exists to explain how these aspects affect microbial fermentation. Here, we hypothesized that wheat bran fractions varying size would be fermented differently gut microbiota, which lead size-dependent differences metabolic fate (as short-chain fatty acids; SCFAs) and community structure. To test this hypothesis, performed an...
Diet, especially with respect to consumption of dietary fibers, is well recognized as one the most important factors shaping colonic microbiota composition. Accordingly, many studies have been conducted explore fiber types that could predictably manipulate for improved health. However, majority these underappreciate vastness structures in terms their microbial utilization and omit detailed carbohydrate structural analysis. In some cases, this causes conflicting results arise between using...
ABSTRACT To reveal the functional properties of hazelnut dietary fibers (DFs) in different colonic segments (cecum, proximal, and distal colon), a diet enriched with natural hazelnut, roasted or skin DFs was applied to mice for 6 weeks; microbial metabolites, composition, tissue morphology were determined segmentally using gas chromatography, 16S rRNA sequencing technology, microscopy, respectively. Roasted revealed significantly ( p < 0.05) higher propionate cecum female mice, while...
ABSTRACT Alternative flours can reveal beneficial health effects. The aim of this study was to evaluate and compare the effects dietary fibers (DFs) coconut carob on colonic microbiota compositions function. Coconut flour DFs were found be dominated by mannose‐containing polysaccharides gas chromatography (GC)/MS spectrophotometer, whereas glucose uronic acid main monosaccharide moieties in DFs. In vitro fecal fermentation analysis revealed that result generation microbial butyrate as much...
Physiologic aging has been associated with gut dysbiosis. Although short exercise interventions have linked to beneficial changes in microbiota younger adults, limited data are available from older populations. We hypothesized that would produce shifts and short-chain fatty acid (SCFA) levels persons.Stool samples were collected before at completion of a supervised 24-week cardiovascular resistance intervention among 50-75-year-old participants. SCFA analyzed by gas chromatography microbiome...
BackgroundHIV-1 infection and physiological aging are independently linked to elevated systemic inflammation changes in enteric microbial communities (dysbiosis). However, knowledge of the direct effect HIV on microbiome potential links is lacking.MethodsIn a cross-sectional study older people living with (PLWH) (median age 61.5 years, N = 14) uninfected controls 58 n 22) we compared stool microbiota, levels metabolites (short-chain fatty acid levels, SCFA) inflammatory biomarkers by...
This study aimed to evaluate and compare the effects of dietary fibers (DFs) commercially important tree nuts (almond, cashew, hazelnut, pistachio, walnut) on gut microbiota in vitro. Microbial compositions short-chain fatty acids were determined using 16S rRNA sequencing gas chromatography (GC), respectively. Neutral acidic monosaccharides analyzed GC/MS spectrophotometry, Our results revealed that cashew exhibit higher butyrate formation compared others. Accordingly, fiber promoted butyric...
Although in vitro studies to identify interactions between food components and the colonic microbiota employ distinct methods mimic upper gastrointestinal (GI) tract digestion, effects of differences protocols on fermentation have not been rigorously addressed. Here, we compared two widely used GI digestion four different cereal brans fermentations by fecal test hypotheses that (1) are varyingly efficient removing accessible starches proteins from dietary (2) these result cereal-specific...
Although many efforts have been made to characterize the functional properties of hazelnut constituents (mainly its oil, protein, and phenolics), those dietary fiber (DF) not elucidated yet. Here, we aimed investigate impact DF natural roasted hazelnuts, skin on colonic microbiota in vivo (C57BL/6J mouse models) by determining their composition through 16S rRNA sequencing microbial short-chain fatty acids (SCFAs) using gas chromatography. Our results revealed that generally showed an...
Differences in the chemical and physical properties of dietary fibers are increasingly known to exert effects on their fermentation by gut microbiota. Here, we demonstrate that maize bran particle size fractions show metabolic output microbial community differences similar those previously observed for wheat brans. As brans, particles varied starch protein content sugar composition with respect size. We fermented varying vitro human fecal microbiota as inocula, measuring fate [i.e.,...
Due to its high nutritional value and health-promoting effects, there is an increasing interest in utilizing chia seed the human diet. The aim of this study was compare compositional functional characteristics white black seeds that are commercially available Turkey. Compositional comparisons were done by quantifying protein, oil, ash moisture contents. total phenolic content antioxidant activity measured using defatted ground seeds. Our results revealed had significantly higher contents,...