Rocío Eirós
A5029630155- Cardiac Imaging and Diagnostics
- COVID-19 Clinical Research Studies
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiomyopathy and Myosin Studies
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Liver Disease Diagnosis and Treatment
- Long-Term Effects of COVID-19
- SARS-CoV-2 and COVID-19 Research
- Genetic Associations and Epidemiology
- Viral gastroenteritis research and epidemiology
- Parathyroid Disorders and Treatments
- interferon and immune responses
- Cardiovascular Effects of Exercise
- Advanced MRI Techniques and Applications
- Protein Kinase Regulation and GTPase Signaling
- COVID-19 and Mental Health
- Pericarditis and Cardiac Tamponade
- Cardiac Structural Anomalies and Repair
- Infective Endocarditis Diagnosis and Management
- Chemotherapy-induced cardiotoxicity and mitigation
- Atrial Fibrillation Management and Outcomes
- Cellular transport and secretion
- Cancer Immunotherapy and Biomarkers
- Sarcoidosis and Beryllium Toxicity Research
Complejo Hospitalario de Salamanca
2021-2025
Instituto de Investigación Biomédica de Salamanca
2020-2025
Centro de Investigación Biomédica en Red
2021-2025
Centro de Investigación en Red en Enfermedades Cardiovasculares
2020-2025
Universidad de Salamanca
2020-2025
Instituto de Salud Carlos III
2025
Centre for Biomedical Network Research on Rare Diseases
2022
Hospital Universitario La Paz
2019-2020
Clinica Universidad de Navarra
2018-2020
Barts Health NHS Trust
2018
Abstract Aims Myocardial scar detected by cardiovascular magnetic resonance has been associated with sudden cardiac death in dilated cardiomyopathy (DCM). Certain genetic causes of DCM may cause a malignant arrhythmogenic phenotype. The concepts left ventricular (LV) (ALVC) and are currently ill-defined. We hypothesized that distinctive imaging phenotype defines ALVC. Methods results Eighty-nine patients DCM-associated mutations [desmoplakin (DSP) n = 25, filamin C (FLNC) 7, titin 30, lamin...
Abstract Background Cardiac sequelae of past SARS-CoV-2 infection are still poorly documented. We conducted a cross-sectional study in health-care workers to report evidence pericarditis and myocarditis after infection. Methods studied 139 with confirmed (103 diagnosed by RT-PCR 36 serology). Participants underwent clinical assessment, electrocardiography, laboratory tests including immune cell profiling cardiac magnetic resonance (CMR). Pericarditis was when classical criteria were present,...
Abstract Aim to describe prognostic cut-off values of RV size and function by cardiac magnetic resonance (CMR) in a multicentre cohort patients with severe TR. Methods results The study-enrolled at least TR (severe, massive torrential) assessed 2D echocardiography who underwent contemporary CMR study. primary endpoint was defined as combined all-cause mortality or hospitalization for heart failure events the secondary cardiovascular mortality. 314 were included this study (70 ± 11 years, 67%...
In hypertensive patients with heart failure (HF) a serum biomarker combination of high carboxy-terminal propeptide procollagen type-I (PICP) and low telopeptide collagen to matrix metalloproteinase-1 (CITP:MMP-1) ratio identifies histomolecular phenotype malignant myocardial fibrosis (mMF) associated severe diastolic dysfunction (DD) poor outcomes. As chronic kidney disease (CKD) facilitates MF DD, we investigated the influence CKD on mMF in HF preserved ejection fraction (HFpEF)....
Abstract Background Some patients infected by SARS-CoV-2 in the recent pandemic have required critical care, becoming one of main limitations health systems. Our objective has been to identify potential markers at admission predicting need for care with COVID-19 pneumonia. Methods We retrospectively collected and analyzed data from electronic medical records laboratory-confirmed SARS-CoV-19 infection real-time RT-PCR. A comparison was made between staying hospitalization ward those who care....
Introduction: Immunotherapy represents a key pillar of cancer treatments, with high response rates and long survival. Its use is increasing, mainly at the expense geriatric population due to ageing this population. However, despite its benefit, safety in certain areas such as cardiotoxicity largely unknown. The aim study assess immunotherapy elderly patients using real-world data. Methods: This an ambispective ≥ 70 years old solid tumours who were treated University Hospital Salamanca....
Background: Right ventricular (RV) to pulmonary circulation (PC) coupling can stratify prognosis in heart failure (HF). In this study, we assessed the prognostic role of mean velocity artery (mvPA) determined by cardiac magnetic resonance (CMR) HF with preserved ejection fraction (HFpEF). Methods: Inclusion 58 HFpEF outpatients that underwent CMR measurement RV–PC parameters including mvPA between 2016 and 2019. The primary combined endpoint was a composite readmissions all-cause mortality....
The genetic basis of severe COVID-19 has been thoroughly studied and many risk factors shared between populations have identified. However, reduced sample sizes from non-European groups limited the discovery population-specific common loci. In this second study nested in SCOURGE consortium, we conducted largest GWAS meta-analysis for hospitalization admixed Americans, comprising a total 4,702 hospitalized cases recruited by other seven participating studies Host Genetic Initiative. We...
The genetic basis of severe COVID-19 has been thoroughly studied, and many risk factors shared between populations have identified. However, reduced sample sizes from non-European groups limited the discovery population-specific common loci. In this second study nested in SCOURGE consortium, we conducted a genome-wide association (GWAS) for hospitalization admixed Americans, comprising total 4702 hospitalized cases recruited by seven other participating studies Host Genetic Initiative. We...
The pathogenesis of COVID‐19 warrants unravelling. Genetic polymorphism analysis may help answer the variability in disease outcome. To determine role KIR and HLA polymorphisms susceptibility, progression, severity SARS‐CoV‐2 infection, 458 patients 667 controls enrolled this retrospective observational study from April to December 2020. Mild/moderate severe/death groups were established. HLA‐A , ‐B ‐C genotyping performed using Lifecodes® HLA‐SSO KIR‐SSO kits on Luminex® 200™ xMAP...