A5060694007- Natural product bioactivities and synthesis
- Traditional Chinese Medicine Studies
- Phytochemistry and Biological Activities
- Adipose Tissue and Metabolism
- Metabolism, Diabetes, and Cancer
- Healthcare and Venom Research
- Pharmacological Effects of Natural Compounds
- Metabolomics and Mass Spectrometry Studies
- Membrane Separation Technologies
- Neurological Disease Mechanisms and Treatments
- Medical Research and Treatments
- Microbial Natural Products and Biosynthesis
- Neurological Disorders and Treatments
- Analytical Methods in Pharmaceuticals
- Peroxisome Proliferator-Activated Receptors
- Traditional Chinese Medicine Analysis
- Membrane-based Ion Separation Techniques
- Network Traffic and Congestion Control
- Nitric Oxide and Endothelin Effects
- Drug Solubulity and Delivery Systems
- Cardiovascular Disease and Adiposity
- Mycorrhizal Fungi and Plant Interactions
- Marine Sponges and Natural Products
- Plant-based Medicinal Research
- Ginseng Biological Effects and Applications
Shandong University
2013-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2021-2025
Institute of Laboratory Animal Science
2025
Ningxia University
2022-2024
State Forestry and Grassland Administration
2024
Xinjiang Agricultural University
2024
Northwest A&F University
2024
China University of Mining and Technology
2023
Jiangnan University
2018-2023
Zhejiang Center for Disease Control and Prevention
2023
Malbranchea circinata SDU050, a fungus derived from deep-sea sediment, is prolific producer of diverse secondary metabolites. Genome sequencing revealed the presence at least 69 biosynthetic gene clusters (BGCs), including 30 encoding type I polyketide synthases (PKSs). This study reports isolation and identification four classes metabolites wild-type M. alongside five additional metabolite classes, three novel cytochalasins (7–9), obtained mutant strain through metabolic blockade strategy....
Traffic Engineering (TE) is a widely-adopted network operation to optimize performance and resource utilization. Destination-based routing supported by legacy routers more readily deployed than flow-based routing, where the forwarding entries could be frequently updated TE accommodate traffic dynamics. However, as size grows, destination-based render high time complexity when generating updating many entries, which may limit responsiveness of degrade performance. In this paper, we propose...
The influence of land granting on green total factor productivity (GTFP) and its mechanisms remain under-explored. Based dynamic spatial panel data 30 provincial administrative regions in China from 2007 to 2017, this study attempts establish the framework a transmission mechanism among granting, manufacturing agglomeration technological innovation, productivity, measures their interactions by mixed directional distance function Global Malmquist–Luenberger index model containing undesirable...
Through metabologenomics mining, we prioritized
Flue gas desulfurization (FGD) wastewater is characterized by low pH, high content of hardness ions and COD. In this work, chemical precipitation ultrafiltration (UF) membrane separation were corporately coupled to treat the FGD on a lab scale remove as well some organic compounds for further advanced treatment. Firstly, influential factors deal with simulated wastewater, including reaction time, stirring speed, dosage, investigated batch tests, while CaO Na2CO3 used first second...
JD27 is a derivatives of active ingredient extracted from Rabdosia which includes functional group 1,2,3-Triazoles. It considered as promising anti-cancer drug candidate because its low toxicity and broad-spectrum activity. However, the clinical application has been limited by poor solubility. Albumin an attractive macromolecular carrier, widely used in nanoparticle preparation. Compared with other delivery systems, drug-loaded albumin nanoparticles showed series advantages such...
High-performance liquid chromatography (HPLC) is an efficient method that widely used to assess the quality of traditional Chinese medicine (TCM). It well known TCM has a direct effect on its efficacy; therefore, in order thoroughly explain how exerts efficacy, it necessary characterize active ingredients and their quality. The application spectrum‑effect crucial for determining pharmacological basis materials. aim present study was examine correlation between chemical spectra estrogenic...
Mounting evidence has linked berries to a variety of health benefits. We previously reported that administration diet rich in black raspberries (BRBs) impacted arsenic (As) biotransformation and reduced As-induced oxidative stress. To further characterize the role gut microbiota BRB-mediated As toxicity, we utilized dietary intervention BRBs combined with mouse model demonstrate microbial changes by examining associated alterations microbiota, especially its functional metabolites. Results...
Emerging applications pose different Quality of Service (QoS) requirements for the network, where Traffic Engineering (TE) plays an important role in QoS provisioning by carefully selecting routing paths and adjusting traffic split ratios on paths. To accommodate diverse flows under network dynamics, TE usually periodically computes optimal strategy updates a significant number forwarding entries, which introduces considerable operation management overhead. In this paper, we propose QoS-RL,...
Introduction Arbuscular mycorrhizal fungi (AMF) are vital in terrestrial ecosystems. However, the community structure characteristics and influencing factors of AMF forest ecosystems arid desert grassland areas require further investigation. Methods Therefore, we employed high-throughput sequencing technology to analyze soil at different elevations Helan mountains. Results The results revealed that significant differences ( P < 0.05) were observed physicochemical properties among...
Metabolic blockade-based genome mining of the marine sediment-derived
In long term evolution (LTE) specification, physical uplink control channel (PUCCH) consists of two basic transmission formats, i.e. formats 1a/1b and format 2, carrying some signals fed back to eNodeB, e.g. ACK/NACK related downlink data blocks quality indicator (CQI). At conventional receiver detection algorithm is do coherent by utilizing reference (RS) based estimation, also called non-blind algorithm, whose performance greatly limited RS density coding rate. this paper, a semi-blind...
Abstract Lymphangiogenesis is possibly capable of attenuating hypertension‐induced cardiac injury. Sirtuin 3 (SIRT3) an effective mitochondrial deacetylase that has the potential to modulate this process; however, its role in lymphangiogenesis date not been investigated. Our experiments were performed on 8‐week‐old wild‐type (WT), SIRT3 knockout (SIRT3‐KO) and overexpression (SIRT3‐LV) mice infused with angiotensin II (Ang II) (1000 ng/kg per minute) or saline for 28 days. After Ang...
1. Bupleuri Radix (BR) is a herbal medicine traditionally used orally in oriental countries, which inevitably comes into contact with the intestinal microbiota. However, whether gut microbiota contribute to biotransformation of BR, and/or formation pharmacologically active compounds remains unknown.2. In this study, main saikosaponins (SAPs) Bupleurum (including saikosaponin a, b1, b2, c, d, f, h) and BR extract (BRE) were individually incubated human fecal suspensions (HFS), metabolic time...
Objectives This study aimed to compare urodynamic studies (UDS) and perineal ultrasonography (US) for the assessment of mixed urinary incontinence (MUI) in women China. Methods Adult with MUI healthy control participants were enrolled from 2 centers China (Zhejiang Beijing) between September 2010 April 2017. Baseline clinical characteristics recorded. The type was categorized by King's Health Questionnaire: stress‐predominant, urge‐predominant, or equal predominance. Urodynamic performed,...