A5100376600- Dementia and Cognitive Impairment Research
- Global Public Health Policies and Epidemiology
- Alzheimer's disease research and treatments
- Myasthenia Gravis and Thymoma
- Nosocomial Infections in ICU
- Pneumonia and Respiratory Infections
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Neuropathies and Disorders
- Retinal Development and Disorders
- Neuroinflammation and Neurodegeneration Mechanisms
- Fetal and Pediatric Neurological Disorders
- Stroke Rehabilitation and Recovery
- Moyamoya disease diagnosis and treatment
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Facial Nerve Paralysis Treatment and Research
- Intraocular Surgery and Lenses
- Intracranial Aneurysms: Treatment and Complications
- Retinal and Macular Surgery
- Atherosclerosis and Cardiovascular Diseases
- Oral microbiology and periodontitis research
- Health Systems, Economic Evaluations, Quality of Life
- Neurological Complications and Syndromes
- Glioma Diagnosis and Treatment
- Long-Term Effects of COVID-19
- Endoplasmic Reticulum Stress and Disease
Samsung Medical Center
2004-2024
Sungkyunkwan University
2020-2024
Montreal Council on Foreign Relations
2016
Korea Institute of Oriental Medicine
2013
Icahn School of Medicine at Mount Sinai
2012
Clinical Research Institute
2011
Seoul National University Hospital
2011
Abstract Previous studies on Alzheimer’s disease-type cognitive impairment (ADCI) and subcortical vascular (SVCI) has rarely explored spatiotemporal heterogeneity. This study aims to identify distinct cortical atrophy patterns in ADCI SVCI. 1,338 participants (713 ADCI, 208 SVCI, 417 cognitively unimpaired elders) underwent brain magnetic resonance imaging (MRI), amyloid positron emission tomography, neuropsychological tests. Using MRI, this measures thickness five regions (medial temporal,...
<i>Background:</i> While the adverse impact of diabetes on microvessels is well known, risks macroangiopathy are less recognized. Here, we determine differential risk and endothelial microparticle (EMP) profile vascular complications in type 2 mellitus. <i>Methods:</i> Macroangiopathy was evaluated for cerebrovascular disease, coronary artery disease peripheral disease; microangiopathy retinopathy, nephropathy neuropathy. Clinical laboratory factors were compared...
Abstract Background Social and hospital environmental factors that may be associated with hospital-acquired pneumonia (HAP) have not been evaluated. Comprehensive risk assessment for the incidence of HAP including sociodemographic, clinical, was conducted using national health insurance claims data. Methods This is a population-based retrospective cohort study adult patients who were hospitalized more than 3 days from Health Insurance Review Assessment Service-National Inpatient Sample data...
Background: Age at onset was suggested as one possible risk factor for motor dysfunction in Alzheimer’s disease (AD). Objective: We investigated the association of symptoms with cognition or neurodegeneration patients AD, and whether this differs by age onset. Methods: included 113 amyloid positive AD divided them into early-onset (EOAD) late-onset (LOAD), who underwent Unified Parkinson’s Disease Rating Scale (UPDRS)-Part III (=UPDRS) scoring, Mini-Mental State Examination (MMSE)/Clinical...
Background: Corticosteroids remain the cornerstone in management of myasthenia gravis (MG). Initiation corticosteroid treatment at a high dose and subsequently decreasing or gradual escalation from low is recommended. We aimed to investigate association between initial regimen response. Methods: A retrospective study was conducted on 234 acetylcholine receptor (AChR) antibody (Ab)–positive MG patients who visited our institution January 2010 February 2023. Patients were grouped based...
Infectious diseases and stroke are common a great health problem worldwide. However, relatively few studies have focused on direct infectious causes of acute stroke, the exact mechanisms associated with infections poorly understood. Herein, we present several organisms that probable stroke. Different pathomechanisms neuroimaging features infection by these discussed. Specifically, distribution cerebral infarction suggests could be cause These include convexity probably due to vasculitis in...
Abstract Background Alzheimer’s disease (AD) is characterized by amyloid beta (Aβ) aggregation [A] and tau reflecting neurofibrillary tangles [T]. These AD markers lead to neurodegeneration [N] cognitive impairments. Recently, the ATN research framework of was presented National Institute on Aging Association. Cerebral small vessel (CSVD, [V]), which one most important cause impairments, has an additive or synergistic effect impairments with markers. In present study, we investigated...
Abstract Background Among the various risk factors for Alzheimer disease (AD), apolipoprotein E (APOE) genotype ε4 is known to be a strong factor. On other hand, ε2 have protective effect. It not yet clear how amyloid positivity according APOE differs by diagnostic criteria. Also, there were no studies showing ethnic difference in effects of on amyloid‐beta (Aβ) between American and Asian. The aim this study was investigate Aβ (Aβ+) genotypes ethnicity cognition. Method We recruited 4,203...
Intraoperative neurophysiological monitoring (IONM) is an important method for detecting and potentially preventing postoperative neurologic deficit. Somatosensory evoked potentials (SSEP) transcranial motor (tcMEP) are widely utilized vascular surgery. A 24-year-old male with bilateral middle cerebral artery (MCA) occlusions, diagnosed moyamoya disease, underwent right superficial temporal (STA)-MCA bypass surgery encephalo-duro-arterio-synangiosis (EDAS). An increase in amplitude of tcMEP...
Preservation of facial nerve function is one the most important goal in cerebellopontine angle (CPA) tumor surgery. To monitor intraoperatively, free-running electromyography (fEMG) monitoring and triggered EMG (tEMG) mapping are used routinely. In addition to those modalities, motor evoked potential (facial MEP) by transcranial electrical stimulation can be helpful predict functional integrity during CPA We found abrupt decrement MEP without definite fEMG change vestibular schwannoma...
Intraoperative visual evoked potential (VEP) monitoring can be useful in surgery involving the pathway. In this report, we report cases with good reproducibility of VEP during for pre-chiasmatic, chiasmatic, and post-chiasmatic lesions. Case studies have shown that used as a tool to monitor functions real time related
Tectal glioma is an indolent and benign tumor that occurs predominantly in the pediatric population. It arises tectum of midbrain and, due to its location, contributes development obstructive hydrocephalus, typically presenting with increased intracranial pressure (IICP) symptoms or signs. Here we report a rare case tectal presented as adult-onset epileptic seizures without IICP was treated endoscopic third ventriculostomy antiepileptic drugs. Key Words: · Hydrocephalus Epilepsy.