A5009489380- Animal Virus Infections Studies
- Viral gastroenteritis research and epidemiology
- Virus-based gene therapy research
- Genetic Mapping and Diversity in Plants and Animals
- Molecular Biology Techniques and Applications
- Forensic and Genetic Research
- Forensic Entomology and Diptera Studies
- SARS-CoV-2 and COVID-19 Research
- Microbial infections and disease research
- Viral Infections and Immunology Research
- Insect and Pesticide Research
- Genetics and Plant Breeding
- Ferroptosis and cancer prognosis
- Soil erosion and sediment transport
- Respiratory viral infections research
- Plant Micronutrient Interactions and Effects
- Advanced biosensing and bioanalysis techniques
- Rice Cultivation and Yield Improvement
- Environmental Toxicology and Ecotoxicology
- RNA Research and Splicing
- DNA and Biological Computing
- Phosphorus and nutrient management
- RNA modifications and cancer
- Bacteriophages and microbial interactions
- Antioxidant Activity and Oxidative Stress
Hainan Medical University
2017-2025
Hebei Normal University of Science and Technology
2018-2025
First Affiliated Hospital of Harbin Medical University
2024
Weatherford College
2024
Jilin Province Tumor Hospital
2024
Harbin Medical University
2024
Center for Excellence in Molecular Plant Sciences
2022-2023
Chinese Academy of Sciences
2012-2023
University of Chinese Academy of Sciences
2022-2023
Shanghai Institutes for Biological Sciences
2023
Starch accounts for up to 90% of the dry weight rice endosperm and is a key determinant grain quality. Although starch biosynthesis enzymes have been comprehensively studied, transcriptional regulation starch-synthesis enzyme-coding genes (SECGs) largely unknown. In this study, we explored role NAC transcription factor, OsNAC24, in regulating rice. OsNAC24 highly expressed developing endosperm. The osnac24 mutants normal appearance as granule morphology, while total content, amylose chain...
In 2006, an emerging highly pathogenic strain of porcine reproductive and respiratory syndrome virus (PRRSV), which causes continuous high fever a proportion deaths in vaccinated pigs all ages, broke out mainland China spread rapidly to neighboring countries. To examine the epidemiology evolutionary characteristics Chinese PRRSV after 2006 outbreak, we tested 2,981 clinical samples collected from 2010 China, determined 153 Nsp2 sequences 249 ORF5 sequences, analyzed genetic diversity PRRSV....
Here we report, for the first time, nearly full-length genome sequence of porcine bocavirus (PBoV), a recently discovered parvovirus from pigs. Phylogenetic trees based on this showed that PBoV belongs to branch containing genus Bocavirus, which comprises canine minute virus (CnMV), bovine parvovirus, gorilla and human (HBoV), was most closely related group CnMV. predicted contain three potential ORFs encoding non-structural protein NS1, characteristic NP1 capsid VP1/VP2, with an...
As a large enveloped RNA virus, coronavirus is of considerable medical and veterinary significance, anticoronavirus treatment challenging due to its biodiversity rapid variability. In this study, Au@Ag nanorods (Au@AgNRs) were successfully synthesized by coating AuNRs with silver shown for the first time have activity against replication porcine epidemic diarrhea virus (PEDV). Viral titer analysis demonstrated that Au@AgNRs could inhibit PEDV infection 4 orders magnitude at 12 h...
Rice is a major food crop that sustains approximately half of the world population. Recent worldwide improvements in standard living have increased demand for high-quality rice. Accurate identification quantitative trait loci (QTLs) rice grain quality traits will facilitate breeding and improvement. In present study, we performed high-resolution QTL mapping using genotyping-by-sequencing approach. An F2 population derived from cross between an elite japonica variety, Koshihikari, indica Nona...
Abstract Age estimation is a critical aspect of forensic entomology, especially in the examination pupae. The use proteins as means for age identification shows great promise. In this study, proteomic techniques were employed to investigate differentially expressed (DEPs) during intrapuparial stage Chrysomya megacephala. Specimens sampled at four distinct time points: 0 h (Group A), 24 B), 48 C), and 72 D). Our analysis uncovered 56 DEPs between Groups B A, 116 C total 152 D A. These...
Epilepsy encompasses a spectrum of chronic brain disorders characterized by transient central nervous system dysfunctions induced recurrent, aberrant, synchronized neuronal discharges. Hippocampal sclerosis (HS) is identified as the predominant pathological alteration in epilepsy, particularly temporal lobe epilepsy. This study investigates metabolic profiles epileptic hippocampal tissues using proteomics and lipidomics techniques. An epilepsy model was established Sprague–Dawley (SD) rats...
Porcine Epidemic Diarrhea Virus (PEDV) and Transmissible Gastroenteritis (TGEV) pose significant threats to neonatal piglets, leading severe diarrhea potentially lethal consequences. Beyond enforcing stringent biosecurity protocols, effective safe vaccinations are crucial in mitigating the impact of these diseases. In this study, PEDV S1 (PS1) TGEV (TS1) antigens were initially chosen as candidates for development circRNA vaccines. Recognizing comparatively lower immunogenicity PS1 antigen...
Grain size and the endosperm starch content determine grain yield quality in rice. Although these components have been intensively studied, their regulatory mechanisms are still largely unknown. In this study, we show that loss-of-function of OsNAC129 , a member NAC transcription factor gene family has its highest expression immature seed, greatly increased length, weight, apparent amylose (AAC), plant height. Overexpression had opposite effect, significantly decreasing width, AAC,...
Diabetic lower limb ischemia is an intractable disease that leads to amputation and even death. Recently, adipose-derived stem cell-secreted exosomes (ADSC-Exo) have been reported as a potential therapeutic approach, but its specific mechanism of action unknown. Studies found derived from cells can reduce inflammation promote tissue repair. Macrophages play important role in the development repair ischemic tissue, regulation ADSC-Exo macrophages has rarely reported. The present study aimed...
Porcine circovirus type 2 (PCV2) is a major emerging virus of porcine circovirus-associated disease (PCVAD), which has brought huge economic losses to the global pig industry. Pigs are well known as natural reservoir PCV2. Recently, many researchers have revealed PCV2 could infect other mammals like mice, calves, minks, dogs and goats. In 2018, our laboratory admitted six cases raccoon from Qinhuangdao city China, were characterized by inappetence, lethargy, depression, abortion,...
To explore genetic mechanism of generalized epilepsies (GGEs) is challenging because their complex heritance pattern and heterogeneity. KCNJ10 gene encodes Kir4.1 channels plays a major role in modulating resting membrane potentials excitable cells. It may cause GGEs if mutated. The purpose this study was to investigate the possible association between common variants susceptibility drug resistance Chinese population. allele-specific MALDI–TOF mass spectrometry method used assess 8 single...
Mycoplasma hyopneumoniae is the etiological agent of porcine enzootic pneumonia (EP), leading to a mild and chronic in swine. Relative control has been attained through active vaccination programs, but remains significant economic challenge swine industry. Cellular immunity plays key role prevention pneumonia. Therefore, development more efficient vaccine that confers strong against M. necessary. In this study, multi-antigen chimera (L9m6) was constructed by combining heat-labile enterotoxin...
Porcine circovirus type 2 (PCV2) is a causative agent of porcine circovirus-associated disease (PCVAD), which serious problem in the swine industry worldwide. In recent years, nonporcine-origin PCV2 has attracted more and attention researchers. This study reported on first identification farmed foxes with reproductive failure. Three fox-origin strains were successfully isolated, sequenced, designated as FoxHB1, FoxHB2, FoxHB3 respectively. Pairwise-sequence comparisons complete genomes...