A5101555056- Colorectal Cancer Surgical Treatments
- Colorectal and Anal Carcinomas
- Enhanced Recovery After Surgery
- Cancer Immunotherapy and Biomarkers
- Economic theories and models
- Cardiac, Anesthesia and Surgical Outcomes
- Colorectal Cancer Treatments and Studies
- Colorectal Cancer Screening and Detection
- Cancer-related gene regulation
- Estrogen and related hormone effects
- Anorectal Disease Treatments and Outcomes
- Clinical practice guidelines implementation
- Economic Growth and Productivity
- Gastric Cancer Management and Outcomes
- Genetic factors in colorectal cancer
- RNA Research and Splicing
- Diverticular Disease and Complications
- Intraperitoneal and Appendiceal Malignancies
- Cancer Genomics and Diagnostics
- Anesthesia and Pain Management
- Esophageal and GI Pathology
- Neuroendocrine Tumor Research Advances
- Nutrition and Health in Aging
- Renal and related cancers
- Heart Failure Treatment and Management
University College Hospital
2025
University College London
2025
Cliniques Universitaires Saint-Luc
2015-2024
Case Western Reserve University
2024
Leeds Teaching Hospitals NHS Trust
2024
UCLouvain
2013-2024
University of Illinois at Springfield
2022
Enanta Pharmaceuticals (United States)
2022
Jazz Pharmaceuticals (France)
2018
l'Assurance Maladie
2018
Optimal control theory is a technique being used increasingly by academic economists to study problems involving optimal decisions in multi-period framework. This textbook designed make the difficult subject of easily accessible while at same time maintaining rigour. Economic intuitions are emphasized, and examples problem sets covering wide range applications economics provided assist learning process. Theorems clearly stated their proofs carefully explained. The development text gradual...
The purpose of this study was to evaluate the prognostic value Immunoscore in patients with stage III colon cancer (CC) and analyze its association effect chemotherapy on time recurrence (TTR).
Abstract Purpose: No biomarker to personalize treatment in locally advanced rectal cancer (LARC) is currently available. We assessed LARC whether a diagnostic biopsy-adapted immunoscore (ISB) could predict response neoadjuvant (nT) and better define patients eligible an organ preservation strategy (“Watch-and-Wait”). Experimental Design: Biopsies from two independent cohorts (n1 = 131, n2 118) of with treated nT followed by radical surgery were immunostained for CD3+ CD8+ T cells quantified...
Tumors of the anus and perianal skin are rare. Their presentation can vary often mimics common benign anal pathology, thereby delaying diagnosis appropriate timely treatment. The anatomy this region is complex because it represents progressive transition from digestive system to with many different co-existing types cells tissues. Squamous cell carcinoma canal most frequent tumor found in region. Less-frequent lesions include Bowen's Paget's disease, basal carcinoma, melanoma,...
To determine whether body fat distribution, measured by waist circumference (WC) and waist/hip ratio (WHR), is a better predictor of mortality morbidity after colorectal surgery than mass index (BMI) or surface area (BSA).Obesity BMI not consistent risk factor for postoperative abdominal surgery. Studies in metabolic cardiovascular diseases have shown WC WHR to be outcome predictors BMI.A prospective multicenter international study was conducted among patients undergoing elective The WHR,...
Background: The prognostic value of Immunoscore was evaluated in Stage II/III colon cancer (CC) patients, but it remains unclear I/II, and early-stage subgroups at risk. An international Society for Immunotherapy Cancer (SITC) study the pre-defined consensus tumors from 1885 AJCC/UICC-TNM I/II CC patients Canada/USA (Cohort 1) Europe/Asia 2). METHODS: Digital-pathology is used to quantify densities CD3+ CD8+ T-lymphocyte center tumor (CT) invasive margin (IM). time recurrence (TTR) primary...
We developed an isolated limb preparation to evaluate the direct vasoactive properties of cardioactive drugs on forearm vasculature in patients with congestive heart failure. Using this model, we infused milrinone subsystemic doses (1, 10, and 20 micrograms/min per 100 ml volume [FAV] ) into brachial artery 13 moderate-to-severe monitored hemodynamics, systemic plasma concentration from both venous effluent pulmonary artery. This enabled us assess vascular response milrinone. Compared...
To determine preoperative tumor-, patient-, and treatment-related factors that are independently associated with incomplete mesorectal excision.Incomplete total excision (TME) for rectal cancer is increased local overall recurrences. Factors predicting have scarcely been studied.In the context of PROCARE, a Belgian multidisciplinary project on cancer, quality 266 consecutive anonymized TME specimens submitted by 33 candidate-TME-trainers was graded blinded pathology review board in...
Abstract Background Research on the relationship between hospital volume and quality of care in treatment rectal cancer is limited. Methods Process outcome indicators were assessed patients with adenocarcinoma who underwent total mesorectal excision, registered a voluntary basis PROCARE clinical database. Volume was derived from an administrative database analysed as continuous variable. Sphincter preservation, 30-day mortality survival rates cross-checked against population-based data....
Nodal stage is a strong prognostic factor of oncological outcome rectal cancer. To compensate for the variation in total number harvested nodes, calculation lymph node ratio (LNR) has been advocated. The aim study was to compare impact, on long-term outcome, LNR with other predictive factors, including quality mesorectal excision (TME) and state circumferential resection margin.Consecutive patients having elective surgery nonmetastatic cancer were extracted from prospectively maintained...