A5077960332- Wireless Communication Networks Research
- Pancreatic function and diabetes
- Advanced Proteomics Techniques and Applications
- GNSS positioning and interference
- Regulation of Appetite and Obesity
- Cancer Genomics and Diagnostics
- Muscle activation and electromyography studies
- Prosthetics and Rehabilitation Robotics
- Zebrafish Biomedical Research Applications
- Indoor and Outdoor Localization Technologies
- MicroRNA in disease regulation
- Hepatocellular Carcinoma Treatment and Prognosis
- Robot Manipulation and Learning
- Cancer, Stress, Anesthesia, and Immune Response
- Pain Mechanisms and Treatments
Neurocentre Magendie
2017-2025
Inserm
2017-2025
Université de Bordeaux
2024-2025
Institut Polytechnique des Sciences Avancées
2024
University of Plymouth
2014
Abstract The hypothalamus contains a remarkable diversity of neurons that orchestrate behavioural and metabolic outputs in highly plastic manner. Neuronal is key to enabling hypothalamic functions and, according the neuroscience dogma, it predetermined during embryonic life. Here, by combining lineage tracing pro-opiomelanocortin (Pomc) with single-cell profiling approaches adult male mice, we uncovered subpopulations ‘Ghost’ endowed atypical molecular functional identity. Compared...
Abstract Strong breakthrough pain is one of the most disabling symptoms cancer since it affects up to 90% patients and often refractory treatments. Alteration in gene expression a known mechanism which microRNAs (miRNAs), class non-coding regulatory RNAs, play crucial role. Here, mouse model pain, we show that miR-124 down-regulated spinal cord, first relay signal brain. Using vitro vivo approaches, demonstrate an endogenous specific inhibitor synaptopodin (Synpo), key protein for synaptic...
Background and Aims Through an exploratory proteomic approach based on typical hepatocellular adenomas (HCAs), we previously identified a diagnostic biomarker for distinctive subtype of HCA with high risk bleeding, already validated multicenter cohort. We hypothesized that the whole protein expression deregulation profile could deliver much more informative data tumor characterization. Therefore, pursued our analysis characterization profiles, evaluating their correspondence established...